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Expression of T cell receptors TcR1 (gamma/delta) and TcR2 (alpha/beta) in the human intestinal mucosa

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Advances in Mucosal Immunology

Abstract

Recent attention has focused on T cells expressing the γ/δ-type T cell receptor (TcRl), although the functional role of TcRl + cells remains speculative [1]. In human peripheral blood, TcRl + γ/δ cells are a minority population of CD4 CD8 “double negatives”. In murine intestinal mucosae, a high proportion of intraepithelial lymphocytes (IEL) are reported to be CD8+ T cells of the γ/δ type [2,3].

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References

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© 1990 Kluwer Academic Publishers

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Trejdosiewicz, L.K., Smart, C.J., Oakes, D.J., Calabrese, A., Howdle, P.D., Boylston, A.W. (1990). Expression of T cell receptors TcR1 (gamma/delta) and TcR2 (alpha/beta) in the human intestinal mucosa. In: MacDonald, T.T., Challacombe, S.J., Bland, P.W., Stokes, C.R., Heatley, R.V., Mowat, A.M. (eds) Advances in Mucosal Immunology. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1848-1_17

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  • DOI: https://doi.org/10.1007/978-94-009-1848-1_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7323-3

  • Online ISBN: 978-94-009-1848-1

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