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Clinical aspects of mucoid Pseudomonas aeruginosa infections

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Pseudomonas Infection and Alginates

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Abstract

Cystic Fibrosis (CF) is an autosomal recessive disease which is most commonly found in Caucasian peoples. In the UK it affects about 1 infant in 2000 (Kuzemko, 1986). The recently isolated gene for CF (Rommens, et al., 1989) is located on the long arm of chromosome number 7 (Wainwright et al., 1985), and genetic probes which lie close to it are already in use for the purposes of prenatal diagnosis (Farrall et al, 1986). The basic biochemical abnormality probably lies at the cellular level but has not yet been identified (Williamson et al, 1983). It is thought to involve a defect in the transport of chloride ions across membranes (Quinton, 1983).

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  1. R. Dinwiddie
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  1. Department of Biochemistry, University of Wales College of Cardiff, Wales

    P. Gacesa  & N. J. Russell  & 

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© 1990 Chapman and Hall

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Dinwiddie, R. (1990). Clinical aspects of mucoid Pseudomonas aeruginosa infections. In: Gacesa, P., Russell, N.J. (eds) Pseudomonas Infection and Alginates. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1836-8_2

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  • DOI: https://doi.org/10.1007/978-94-009-1836-8_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7319-6

  • Online ISBN: 978-94-009-1836-8

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