The gastric lymphomas and the role of Helicobacter pylori in tumour development: have criteria been set for diagnosis?

  • M. F. Dixon


Gastric lymphomas account for only a small proportion of gastric malignancies, between 1% and 7% depending on the geographical area1, but their incidence is increasing2. Almost all are B-cell lymphomas, a proportion of which recapitulate the appearances of mucosa-associated lymphoid tissue (MALT) and are similar to low-grade B-cell lymphomas arising in the lung, thyroid and salivary gland3. As with these latter two sites, the stomach has no intrinsic lymphoid tissue. It is now clear that the appearance of a lymphoid infiltrate in the gastric mucosa is largely a consequence of H. pylori infection. Thus it can be anticipated that H. pylori gastritis is a major precursor of gastric lymphoma, and evidence to this effect has accumulated over recent years.


Pylorus Infection Chronic Gastritis Mucosa Associate Lymphoid Tissue Follicular Dendritic Cell Marginal Zone Lymphoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Kluwer Academic Publishers and Axcan Pharma 1996

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  • M. F. Dixon

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