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Vaccines for the treatment and prevention of Helicobacter pylori infection

  • I. Corthésy-Theulaz
  • A. L. Blum
  • J.-P. Kraehenbuhl

Abstract

An immunological approach or a vaccine approach to clear chronic Helicobacter pylori infection was initially rejected by many investigators and clinicians, based on the observation that natural immunity was unable to cure or prevent Helicobacter infection and chronic atrophic gastritis. Recent animal studies, however, have established that immunization with Helicobacter whole cell extracts or purified components is efficient for the prevention of infection, and more importantly for the treatment of pre-existing infections. Therefore there is now considerable interest in the design of Helicobacter vaccines, which represent a promising alternative to conventional therapies, in which bad compliance and antibiotic resistance represent serious drawbacks1.

Keywords

Pylorus Infection Cholera Toxin Gastric Epithelial Cell Oral Immunization Pylorus Antigen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers and Axcan Pharma 1996

Authors and Affiliations

  • I. Corthésy-Theulaz
  • A. L. Blum
  • J.-P. Kraehenbuhl

There are no affiliations available

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