Abstract
Biosensors are analytical devices that transduce biological reactions into electrical signals. The unique feature of a biosensor is that the probe incorporates a biological sensing element close to the signal transducer, resulting in a device that is specific either for a particular chemical or for a group of related chemicals (Figure 7.1). Although the major thrust in biosensor development since the early 1970s has been for health care applications, a survey of the market potential (Hall, 1990) has identified the increasing importance of biosensors in environmental monitoring.
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References
Aizawa, M., Morioka, A. and Suzuki, S. (1978) Electrochemical determination of IgG, Journal of Membrane Science, 4, 221–226.
Aizawa, M., Suzuki, S., Nagamura, Y., Shinohara, R. and Ishiguro, J. (1979a) Enzyme immunoassay for human chorionic gonadotropin with electrochemical detection. Journal of Solid-phase Biochemistry, 4, 25–30.
Aizawa, M., Morioka, A., Suzuki, S. and Nagamura, Y. (1979b) Enzyme immunosensor III. Amperometric determination of human chorionic gonadotropin by membrane bound antibody. Analytical Biochemistry, 94, 22–28.
Albery, W.J., and Cranston, D.H. (1987) Amperometric enzyme electrodes: theory and experiment. In Biosensors: Fundamentals and Applications, (ed. A.P.F. Turner, I. Karube and G.S. Wilson), pp. 180–210. Oxford University Press, Oxford.
Alder, J.F. and McCallum, J.J. (1983) Piezoelectric crystals for mass and chemical analysis.Analyst, 108, 1169–1189.
Allen, C. (1994) Thunder and Lightning: The RAF in the Gulf Warner Books, London.
Alvarez-Icaza, M. and Bilitewski, U. (1993) Mass production of biosensors. Analytical Chemistry, 65, 525A–533A.
Alvarez-Icaza, M. and Scmid, R.D. (1994) Observation of direct electron transfer from the active centre of glucose oxidase to a graphite electrode achieved through the use of mild immobilisation. Bioelectrochemistry and Bioenergetics, 33, 191–199.
Ariga, O., Takagi, H., Nishizawa, H. and Sano, Y. (1987) Immobilization of microorganisms with PVA hardened by iterative freezing and thawing. Journal of Fermentation Technology, 65, 651–658.
Arnold, M.A. and Rechnitz, G.A. (1980) Comparison of bacterial, mitochondrial, tissue and enzyme biocatalysts for glutamine selective membrane electrodes. Analytical Chemistry, 52, 1170–1174.
Arnold, M.A. and Rechnitz, G.A. (1987) Biosensors based on plant and animal tissue. In Biosensors: Fundamentals and Applications, (ed. A.P.F. Turner, I. Karube and G.S. Wilson), Oxford University Press, Oxford, pp. 35–78.
Arwin, H., Lundström, I. and Palmqvist, A. (1982) Electrode adsorption method for the determination of enzymatic activity. Medical and Biological Engineering Computation, 20, 362–374.
Atkinson, A.L. and Rawson, D.M. (1994) Biosensors for pollution monitoring and toxicity assessment. In Ecotoxicology of Soil Organisms, (ed. M.H. Donker, H. Eijsackers and F. Heimbach), Lewis, Boca Raton, FL, pp. 68–92.
Bains, W. (1994) A spectroscopically interrogated flow-through type toxicity biosensor. Biosensors and Bioelectronics, 9, 111–117.
Bartlett, P.N. and Cooper, J.M. (1993) A review of the immobilisation of enzymes in electropolymerised films. Journal of Electroanalytical Chemistry, 362, 1–12.
Bartlett, P.N. and Whitaker, R.G. (1987a) Electrochemical immobilisation of enzymes, Part II. Glucose oxidase immobilised in poly-N-methylpyrrole. Journal of Electroanalytical Chemistry, 224, 37–48.
Bartlett, P.N. and Whitaker, R.G. (1987b) Electrochemical immobilisation of enzymes, Part I. Theory. Journal of Electroanalytical Chemistry, 224, 27–35.
Bartlett, P.N., Tebbutt, P. and Tyrrell, C.H. (1992) Electrochemical immobilisation of enzymes, Part III. Immobilisation of glucose oxidase in thin films of electrochemically polymerised phenols. Analytical Chemistry, 64, 138–142.
Bennetto, H.P., Box, J., Delaney, G.M., Mason, J.R., Roller, S.D., Stirling, J.L. and Thurston, C.F. (1987) Redox-mediated electrochemistry of whole micro-organisms; from fuel cells to biosensors. In Biosensors: Fundamentals and Applications, (ed. A.P.F. Turner, I. Karube and G. S. Wilson), Oxford University Press, Oxford, pp. 291–314.
Bitton, G., Dutton, R.J. and Koopman, B. (1988) Cell permeability to toxicants: an important parameter in toxicity test using bacteria. CRC Critical Reviews in Environmental Control, 18, 177–188.
Blaedel, W.J. and Jenkins, R.A. (1972) Study of a reagentless lactate electrode. Analytical Chemistry, 48, 1240–1247.
Blake, C. and Gould, B.J. (1984) Use of enzymes in immunoassay techniques: a review.Analyst, 109, 533–547.
Breyer, B. and Radcliffe, F.J. (1951) Polarographic investigations of the antigen antibody reaction. Nature (London), 167, 79.
Buch, R.M., Barker, T.Q. and Rechnitz, G.A. (1991) Intact chemoreceptors based on Hawaiian aquatic species. Analytica Chimica Acta, 243, 157–166.
Campanella, L., Paoletti, A.M. and Tranchida, G. (1987) Biosensors of total toxicity. Chimicaoggi, March, 61–63.
Cardosi, M.F. (1994) Hydrogen peroxide-sensitive electrode based on horseradish peroxidase-modified platinised carbon. Electroanalysis, 6, 89–96.
Cardosi, M.F. and Birch, S.W. (1993) Screen printed glucose electrodes based on platinised carbon particles and glucose oxidase. Analytica Chimica Acta, 276, 69–74.
Cardosi, M.F. and Turner, A.P.F. (1991) Mediated electrochemistry: a practical solution to biosensing. In Advances in Biosensors, Vol. 1, (ed. A.P.F. Turner), pp. 125–169. JAI Press, London.
Cardosi, M.F., Birch, S.W., Talbot, J. and Phillips, A. (1991) An electrochemical immunoassay for Clostridium perfringens phospholipase C. Electroanalysis, 3, 169–176.
Carr, P.W. and Bowers, L.D. (1980) Immobilised enzymes in analytical and clinical chemistry. In Advances in Biochemical Engineering, Vol. 15, (ed. A. Fiechter), pp. 89–129. Springer Verlag, Berlin.
Cass, A.E.G. (ed.) (1990) Biosensors: A Practical Approach. IRL Press, Oxford.
Cooper, J. and Hall, E.A.H. (1993) Catalytic reduction of benzoquinone at polyaniline and polyaniline/enzyme films. Electroanalysis, 5, 385–397.
Corcoran, C.A. and Kobos, R.K. (1987) Selectivity enhancement of an Escherichia coli bacterial electrode using enzyme and transport inhibitors. Biotechnology and Bioengineering, 30, 565–570.
Corcoran, C.A. and Rechnitz, G.A. (1985) Cell-based biosensors. Trends in Biotechnology, 3, 92–96.
Cottrell, F.G. (1902) Der Restrom bei galvanischer Polarisation, betratchet als ein Diffusionproblem. Zeitschrift für physik Chemie, XLII, 385–431.
Deshpande, M.V. and Hall, E.A.H. (1990) An electrochemically grown polymer as an immobilisation matrix for whole cells: application in an amperometric dopamine sensor. Biosensors and Bioelectronics, 5, 431–448.
Diaz, A. (1981) Electrochemical preparation and characterisation of conducting polymers. Chemica Scripta, 17, 145–148.
Dicks, J.M., Cardosi, M.F., Turner, A.P.F. and Karube, I. (1993) The application of ferrocene-modified n-type silicon in glucose biosensors. Electroanalysis, 5, 1–9.
Dorward, E.J. and Barisas, B.G. (1984) Acute toxicity screening of water pollutants using a bacteria electrode. Environmental Science and Technology, 18, 967–972.
Doyle, M.J., Halsall, H.B. and Heinemann, W.R. (1982) A heterogeneous immunoassay for serum proteins by differential pulse anodic stripping voltammetry. Analytical Chemistry, 54, 2318–2322.
Eddowes, M. (1990) Theoretical methods for analysing biosensor performance. In Biosensors: A Practical Approach, (ed. A.E.G. Cass), pp. 211–262. IRL Press, Oxford.
Elliot, C.M. and Murray, R.W. (1976) Chemically modified carbon electrodes. Analytical Chemistry, 48, 1247–1254.
Evans, G.P., Johnson, D. and Withell, C. (1986) Development of the WRc Mk III fish monitor: description of the system and its response to some commonly encountered pollutants. WRc Environmental Report TR233, WRc Medmenham, UK.
Evans, J.F. and Kuwana, T. (1977) Introduction of functional groups onto carbon electrodes via treatment with radio-frequency plasma. Analytical Chemistry, 51, 358–365.
Fersht, A. (1985) Enzyme Structure and Mechanism, 2nd edn, Freeman, New York.
Foulds, N.C. and Lowe, C.R. (1988) Immobilisation of glucose oxidase in ferrocene-modified pyrrole polymers. Analytical Chemistry, 60, 2473–2478.
Gaisford, W.C., Richardson, N.J., Haggett, B.G.D. and Rawson, D.M. (1991) Microbial biosensors for environmental monitoring. Biochemical Society Transactions, 19, 15–18.
Gamati, S., Luong, J.H.T. and Mulchandani, A. (1991) A microbial biosensor for trimethyla- mine using Pseudomonas aminovarans cells. Biosensors and Bioelectronics, 6, 125–131.
Gayet, J.-C, Haouz, A., Geloso-Meyer, A. and Burstein, C. (1991) Detection of heavy metal salts with biosensors built with an oxygen electrode coupled to various immobilised oxidases and dehydrogenases. Biosensors and Bioelectronics, 6, 55–72.
Goodson, L.H. and Jacobs, W.B. (1974) Application of immobilised enzymes to detection and monitoring. In Enzyme Engineering, Vol. 2, (ed. K.E. Pye and L.B. Wingard, Jr), pp. 393–400. Plenum Press, New York.
Goodson, L.H. and Jacobs, W.B. (1976) Monitoring of air and water for enzyme inhibitors. In Methods in Enzymology, Vol. 44, (ed. S.P. Colwick and N.O. Kaplan), pp. 647–658. Academic Press, New York.
Gough, D.A. and Leypoldt, J.K. (1981) Theoretical aspects of enzyme electrode design. Applied Biochemistry and Bioengineering, 3, 175–200.
Gregg, B.A. and Heller, A. (1990) Cross-linked redox gels containing glucose oxidase for amperometric biosensor applications. Analytical Chemistry, 62, 258–263.
Guilbault, G.G. and Jordan, J. (1988) Analytical uses of piezoelectric crystals. CRC Reviews, 19, 28–60.
Guilbault, G.G. and Schmid, R. (1991) Electrochemical, piezoelectric and fibre-optic biosensors. In Advances in Biosensors (ed. A.P.F. Turner), JAI Press Ltd, London, pp. 257–289.
Hall, D.O. and Rao, K.K. (1994) Photosynthesis. Cambridge University Press, UK.
Hall, E. (1990) Biosensors. Open University Press, Milton Keynes.
Hall, G.F., Best, D.J. and Turner, A.P.F. (1988a) The Determination of p-cresol in chloroform with an enzyme electrode used in the organic phase. Analytica Chimica Acta, 213, 113–119.
Hall, G.F., Best, D.J. and Turner, A.P.F. (1988b) Amperometric enzyme electrode for the determination of phenols in chloroform. Enzyme and Microbial Technology, 10, 543–546.
Hart, J.P. and Wring, S.A. (1994) Screen-printed voltammetric and amperometric electrochemical sensors for decentralised testing. Electroanalysis, 6, 617–624.
Hertl, W. (1987) Amperometric immunoassays. Bioelectrochemistry and Bioenergetics, 17, 89–100.
Jeanfils, J. (1986) Immobilization of whole cells of green algae or cyanobacteria in insoluble matrices. Morphological observations and nitrate reductase activity of immobilized cells. Archives of Biology (Bruxelles), 97, 209–222.
Karube, I. (1987) Micro-organism based sensors. In Biosensors: Fundamentals and Applications, (ed. A.P.F. Turner, I. Karube and G.S. Wilson), pp. 13–29. Oxford University Press, Oxford, UK.
Karube, I. and Tamiya, T. (1987) Biosensors for environmental control. Pure and Applied Chemistry, 59, 545–554.
Karube, I., Hiramoto, K., Kawarai, M. and Sode, K. (1989) Biosensor for toxic compounds using immobilized animal cell membrane. Membrane, 14, 311–318.
Kong, Z., Vanrolleghem, P.A. and Verstraete, W. (1993) An activated sludge-based biosensor for rapid IC50 estimation and on-line toxicity monitoring. Biosensors and Bioelectronics, 8, 49–58.
Kuek, C. and Armitage, T.M. (1985) Scanning electronmicroscopic examination of calcium alginate beads immobilising growing mycelia. Enzyme and Microbial Technology, 1, 121– 125.
Kulys, L. and D’Costa, E.J. (1991) Printed electrochemical sensor for ascorbic acid determination. Analytica Chimica Acta, 243, 173–178.
Labuda, J. (1992) Chemically modified electrodes as sensors in analytical chemistry. Selective Electrode Reviews, 14, 33–86.
Laidler, K.J. and Bunting, P.S. (1973) The Chemical Kinetics of Enzyme Action, 2nd edn, Clarendon Press, Oxford.
Lee, S., Sode, K., Nakanishi, K., Marty, J.-L., Tamiya, E. and Karube, I. (1992) A novel microbial sensor using luminous bacteria. Biosensors and Bioelectronics, 7, 273–277.
Levich, V.G. (1962) Physiochemical Hydrodynamics. Prentice-Hall, Englewood Cliffs, NJ.
Li, F., Tan T.C. and Lee, Y.K. (1994) Effects of pre-conditioning and microbial composition on the screening efficacy of a BOD biosensor. Biosensors and Bioelectronics, 9, 197–205.
Li, F. and Tan T.C. (1994b) Monitoring BOD in the presence of heavy metal ions using a poly(4-vinylpyridine)-coated microbial sensor. Biosensors and Bioelectronics, 9, 445–455.
Li, F. and Tan T.C. (1994a) Effect of heavy metal ions on the efficacy of a mixed Bacilli BOD sensor. Biosensors and Bioelectronics, 9, 315–324.
Li, Y.-R. and Chu, J. (1991) Study of BOD microbial sensors for waste water treatment control. Applied Biochemistry and Biotechnology, 28/29, 855–863.
Liang, B.S., Li, X.-M. and Wang, H.Y. (1986) Cellular electrode for antitumor drug screening. Biotechnology Progress, 2, 187–191.
Lin, A.W.C., Yeh, P., Yacynych, A.M. and Kuwana, T. (1977) Cyanuric chloride as a general linking agent for the attachment of redox groups to pyrolytic graphite and metal oxide electrodes. Journal of Electroanalytical Chemistry, 84, 411–419.
Macholán, L. and Boháckoá, I. (1988) Non-traditional membrane biocatalysts for amperometric enzyme electrodes sensing phenolic substances. Biologia (Bratislava), 43, 1121–1130.
Macholán, L. and Schanel, L. (1977) Enzyme electrode with immobilised polyphenol oxidase for determination of phenolic substrates. Collection of Czechoslovak Chemical Communications, 42, 3667–3675.
Macritchie, F. (1978) Dynamics of protein adsorption. Advances in Protein Chemistry, 32, 283–289.
Martens, N. and Hall, E.A.H. (1994) Diaminodurene as a mediator of a photocurrent using intact cells of cyanobacteria. Photochemistry and Photobiology, 59, 91–98.
Mascini, M. and Palleschi, G. (1989) Design and applications of enzyme electrode probes. Selective Electrode Review, 11, 191–264.
Matsunaga, T., Tomoda, R. and Matsuda, H. (1984) Photomicrobial electrode for the selective determination of sulphide. Applied Microbiology and Biotechnology, 19, 404–408.
Mattiasson, B. and Nilsson, H. (1977) Competitive immunoelectrode for the determination of albumin. Febs Lett 78, 251–256.
Mattiasson, B., Nilsson, H. and Olsson, B. (1979) An apoenzyme electrode. Journal of Applied Biochemistry, 1, 377–384.
McNeil, C.J. Bannister, J.V. and Higgins, I.J. (1988) Amperometric determination of alkaline phosphatase activity: application to immunoassays. Biosensors, 3, 199–209.
Mell, L.D. and Maloy, J.T. (1975) A model for the amperometric enzyme electrode obtained through digital simulation and applied to the glucose oxidase system. Analytical Chemistry, 47, 299–307.
Moses, P.R., Wier, L. and Murray, R.W. (1975) Chemically modified tin oxide electrode. Analytical Chemistry, 47, 1882–1886.
Muramatsu, H., Kajiwara, K., Tamiya, E. and Karube, I. (1986) Piezoelectric immunosensor for the detection of Candida albicans microbes. Analytica Chimica Acta, 188, 257–261.
Murray, R.W. (1980) Chemically modified electrodes. Accounts of Chemical Research, 13, 135–141.
Ngeh-Ngwainbi, J., Foley, P.H., Kuan, S.S. and Guilbault, G.G. (1986) Parathion antibodies on piezoelectric crystals. Journal of the American Chemical Society, 108, 5444–5450.
Nishikawa, S., Sakai, S., Karube, I., Matsunaga, T. and Suzuki, S. (1982) Dye-coupled electrode system for the rapid determination of cell populations in polluted water. Applied and Environmental Microbiology, 43, 814–818.
Owicki, J.C. and Parce, J.W. (1990) Bioassays with a microphysiometer. Nature, 344, 271–272.
Owicki, J.C. and Parce, J.W. (1992) Biosensors based on the energy metabolism of living cells: the physical chemistry and cell biology of extracellular acidification. Biosensors and Bioelectronics, 7, 255–272.
Oyama, N., Ohsaka, T., Mizunuma, M. and Kobayashi, M. (1988) Electropolymerised cobalt tetrakis (o-aminophenyl) porphyrin film mediated enzyme electrode for amperometric determination of glucose. Analytical Chemistry, 60, 2534–2536.
Palmquist, E., Kriz, C.B., Khayyami, M., Danielson, B., Larsson, P.-O., Mosbach, K. and Kriz, D. (1994) Development of a simple detector for microbial metabolism, based on a polypyrrole DC resistometric device. Biosensors and Bioelectronics, 9, 551–556.
Pandard, P. and Rawson, D.M. (1993) An amperometric algal biosensor for herbicide detection employing a carbon cathode oxygen electrode. Environmental Toxicology and Water Quality: An International Journal, 8, 323–333.
Pandard, P., Vasseur, P. and Rawson, D.M. (1993) Comparison of two types of sensors using eukaryotic algae to monitor pollution of aquatic systems. Water Research, 27, 427–431.
Rawson, D.M., Willmer, A.J. and Cardosi, M.F. (1987) The development of whole cell biosensors for on-line screening of herbicide pollution of surface waters. Toxicity Assessment, 2, 325–340.
Rawson, D.M., Willmer, A.J. and Turner, A.P.F. (1989) Whole-cell biosensors for environmental monitoring. Biosensors, 4, 299–311.
Rechnitz, G.A., Kobos, R.K., Riechel, S.J. and Gebauer, C.R. (1977) A bio-selective membrane electrode prepared with living bacterial cells. Analytica Chimica Acta, 94, 357–365.
Richardon, N.J., Gardner, S. and Rawson, D.M. (1991) A chemically mediated amperometric biosensor for monitoring eubacterial respiration. Journal of Applied Bacteriology, 70, 422–426.
Riedel, K. (1991) Biochemical fundamentals and improvement of the selectivity of microbial biosensors — a minireview. Bioelectrochemistry and Bioenergetics, 25, 19–30.
Riedel, K. (1994) The alternative to BOD5: ARAS-SensorBOD. Application Report Bio Nr.202. Dr Bruno Lange, GmbH, Berlin.
Riedel, K., Renneberg, R., Kühn, M. and Scheller, F. (1988a) A fast estimation of biological oxygen demand using microbial sensors. Applied Microbiology and Biotechnology, 28, 316–318.
Riedel, K., Renneberg, R. and Liebs, P. (1988b) Biochemical basis of a kinetically controlled microbial sensor. Bioelectrochemistry and Bioenergetics, 19, 137–144.
Riedel, K., Naumov, A.V., Grishenkov, V.G., Boronin, A.M., Stein, HJ., Scheller, F. and Mueller, H.-G. (1989) Plasmid-containing microbial sensor for (δ-caprolactam. Applied Microbiology and Biotechnology, 31, 502–504.
Riedel, K., Huth, J., Kuehn, M. and Liebs, P. (1990a) Amperometric determination of ammonium ions with a microbial sensor. Journal of Chemical Technology and Biotechnology, 41, 109–116.
Riedel, K., Lange, K.-P., Stein, H.-J., Kühn, M., Ott, P. and Scheller, F. (1990b) A microbial sensor for BOD. Water Research, 24, 883–887.
Riedel, K., Naumov, A.V., Boronin, A.M., Golovleva, L.A., Stein, H.J. and Scheller, F. (1991) Microbial sensors for determination of aromatics and their chloroderivatives. I. Determination of 3-chlorobenzoate using a Pseudomonas-contaimng biosensor. Applied Microbiology and Biotechnology, 35, 559–562.
Roit, I. (1980) Essential Immunology, 4th edn., Blackwell Scientific, Boston.
Romette, J.L. and Boitieux, J.L. (1984) Oxidase enzyme: enzyme and immunoenzyme sensor. Annals of the New York Academy of Sciences, 434, 533–535.
Romette, J.L., Yang, J.S., Kusakabe, H. and Thomas, D. (1983) Enzyme electrode for the specific determination of l-lysine. Biotechnology and Bioengineering, 25, 2557–2566.
Rosen, I. and Rishpon, J. (1989) Alkaline phosphatase as a label for heterogeneous immunochemical sensors: an electrochemical study. Journal of Electroanalytical Chemistry, 258, 27–39.
Saini, S., Hall, G.F., Downs, M.E.A. and Turner, A.P.F. (1991) Organic phase enzyme electrodes. Analytica Chimica Acta, 249, 1–15.
Sauerbrey, G.Z. (1959) Use of a quartz vibrator for weighing thin layers on a microbalance. Zeitschrift Physik, 155, 206–210.
Scheller, F. and Schubert, F. (1992) Biosensors. Elsevier, Amsterdam.
Schubert, F., Renneberg, R., Scheller, F.W. and Kirstein, L. (1984) Plant tissue hybrid electrode for determination of phosphate and fluoride. Analytical Chemistry, 56, 1677–1682.
Shaolin, M., Huaiguo, X. and Biding, Q. (1991) Bioelectrochemical response of the polyaniline glucose oxidase electrode. Journal of Electroanalytical Chemistry, 302, 7–16.
Shons, A., Dorman, F. and Najarian, J. (1972) Immunospecific microbalance. Journal of Biomedical and Material Research, 6, 565–670.
Sidwell, J.S. and Rechnitz, G.A (1985) ‘Bananatrode’ — an electrochemical sensor for dopamine. Biotechnology Letters, 7, 419–422.
Skladal, P. and Mascini, M. (1992) Sensitive detection of pesticides using amperometric sensors based on cobalt phthalocynaine-modified composite electrodes and immobilized cholinesterases. Biosensors and Bioelectronics, 7, 335–343.
Starostina, N.G., Lusta, K.A. and Fikhte, B.A. (1983) Prediction of microbial resistance to immobilization in Polyacrylamide gel. Translated from Prikladnaya Biokhimiya I Mikrobiologiya, 19, 369–371.
Tan, H.-M., Cheong, S.-P. and Tan, T.-C. (1994) An amperometric benzene sensor using whole cell Pseudomonas putida ML2. Biosensors and Bioelectronics, 9, 1–8.
Tan, T.C., Li, F., Neoh, K.G. and Lee, Y.K. (1992) Microbial membrane-modified dissolved oxygen probe for rapid biochemical oxygen demand measurement. Sensors and Actuators B, 8, 167–172.
Tan, T.C., Li, F. and Neoh, K.G. (1993) Measurement of BOD by initial rate of response of a microbial sensor. Sensors and Actuators B, 10, 137–142.
Tsushima, R., Kondo, A., Sakata, M. and Kawabata, N. (1992) Preparation of bacteria-adsorption polymer and its application to biosensor. Polymeric Materials Science and Engineering, 66, 437–438.
Turner, A.P.F., Karube, I., and Wilson, G.S. (ed.) (1987) Biosensors: Fundamentals and Applications, Oxford University Press, Oxford.
Walsh, CT. (1977) Enzymatic Reaction Mechanisms. Freeman, New York.
Walters, R.R., Moriarty, B.E. and Buck, R.P. (1980) Pseudomonas bacterial electrode for determination of l-histidine. Analytical Chemistry, 52, 1680–1684.
Weber, S.G. and Purdy, W.C. (1979) Homogeneous voltammetric immunoassay. Analytical Letters, 12, 1–9.
Wehmeyer, K.R., Halsall, H.B. and Heinemann, W.R. (1982) Electrochemical investigation of hapten-antibody interactions by differential pulse polarography. Clinical Chemistry, 28, 1968–1972.
Wijesuriya, D.C. and Rechnitz, G.A. (1993) Biosensors based on plant and animal tissues. Biosensors and Bioelectronics, 8, 155–160.
Wring, S.A. and Hart, J.P. (1992) Chemically modified, screen printed carbon electrodes. Analyst, 117, 1281–1286.
Yamamoto, N., Nagasawa, Y., Sawai, M., Sudo, T. and Tsubomura, H. (1978) Potentiometrie investigations of antigen-antibody and enzyme-enzyme inhibitor reactions using chemically modified metal electrodes. Journal of Immunological Methods, 22, 309–317.
Yamamoto, N., Nagaoka, S., Tanaka, T., Shiro, T., Honma, K. and Tsubomura, H. (1983) Potentiometrie detection of biological substances by using chemically modified electrodes. Analytical Chemistry Symposium Series, No. 17 (Chemical Sensors), pp. 699–704.
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Cardosi, M., Haggett, B. (1997). Biosensor devices. In: Campbell, M. (eds) Sensor Systems for Environmental Monitoring. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1571-8_7
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