Abstract
The ability of biomolecules to recognize other molecules (molecular recognition) is fundamental to biochemistry, and serves as the basis of molecular medicine and therapeutics. Receptor-ligand, enzyme-substrate (inhibitor), antibody-antigen are the general classes of such interactions that have found important application in the treatment of human disease. The measurement of the thermodynamic parameters that govern molecular recognition is an important step in characterizing any such molecular system and is generally termed affinity analysis. Affinity analysis is therefore broadly defined as any technique that exploits the chemical affinity of one molecule for another in order to measure the thermodynamic parameters that govern the interaction.
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© 1997 Chapman & Hall
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Wiktorowicz, J.E. (1997). Affinity analysis by capillary electrophoresis. In: Shintani, H., Polonský, J. (eds) Handbook of Capillary Electrophoresis Applications. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1561-9_21
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DOI: https://doi.org/10.1007/978-94-009-1561-9_21
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7197-0
Online ISBN: 978-94-009-1561-9
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