Skip to main content

Abstract

Capillary electrophoresis (CE) has recently become an important technique in the separation analysis field. In 1967, Hjertén successfully achieved free-zone electrophoresis in a narrow-bore tube of 3 mm inner diameter [1]. His pioneering work was followed by Virtanen [2] and Mikkers et al. [3]. Jorgenson and Lukacs have improved the technique substantially with capillaries of inner diameter less than 100µm [4–6]. They demonstrated the characteristics of modern CE, i.e. the sufficient dissipation of heat resulting from high applied voltage, on-column detection and the high-efficiency separation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Hjerten, S. (1967) Free zone electrophoresis. Chromatogr. Rev. 9, 122–219.

    Article  CAS  Google Scholar 

  2. Virtanen, R. (1974) Zone electrophoresis in a narrow-bore tube employing potentiometric detection. A theoretical and experimental study. Acta Polytech. Scand. 123, 1–67.

    Google Scholar 

  3. Mikkers, F.E.P.; Everaerts, F.M.; Verheggen, T.P.E.M. (1979) High-performance zone electrophoresis. J. Chromatogr. 169, 11–20.

    Article  CAS  Google Scholar 

  4. Jorgenson, J.W.; Lukacs, K.D. (1981) Zone electrophoresis in open-tubular glass capillaries. Anal. Chem. 53, 1298–1302.

    Article  CAS  Google Scholar 

  5. Jorgenson, J.W.; Lukacs, K.D. (1981) High-resolution separations based on electrophoresis and electroosmosis. J. Chromatogr. 218, 209–216.

    Article  CAS  Google Scholar 

  6. Green, J.S.; Jorgenson, J.W. (1984) High speed zone electrophoresis in open-tubular fused silica capillaries. J. High Resolut. Chromatogr. 7, 529–531.

    Article  CAS  Google Scholar 

  7. Li, S.F.Y. (1992) Capillary Electrophoresis: Principles, Practice, and Applications; Elsevier, Amsterdam.

    Google Scholar 

  8. Jandik, P.; Bonn, G. (1993) Capillary Electrophoresis of Small Molecules and Ions; VCH Publishers, New York.

    Google Scholar 

  9. Grossman, P.D.; Colburn, J.C. (eds) (1992) Capillary Electrophoresis: Theory and Practice; Academic Press, San Diego.

    Google Scholar 

  10. Kuhn, R.; Hoffstetter-Kuhn, S. (1993) Capillary Electrophoresis: Principles and Practice; Springer-Verlag, Berlin.

    Google Scholar 

  11. Monnig, C.A.; Kennedy, R.T. (1994) Capillary electrophoresis. Anal. Chem. 66, 280R-314R.

    Article  CAS  Google Scholar 

  12. Marina, M.L.; Torre, M. (1994) Capillary electrophoresis. Talanta 41, 1411–1433.

    Article  CAS  Google Scholar 

  13. Knox, J.H. (1994) Terminology and nomenclature in capillary electroseparation systems. J. Chromatogr. 680, 3–13.

    Article  CAS  Google Scholar 

  14. Terabe, S.; Otsuka, K.; Nishi, H. (1994) Separation of enantiomers by capillary electrophoretic techniques. J. Chromatogr. 666, 295–319.

    Article  CAS  Google Scholar 

  15. Taylor, J.A.; Yeung, E.S. (1993) Imaging of hydrodynamic and electrokinetic flow profiles in capillaries. Anal. Chem. 65, 2928–2932.

    Article  CAS  Google Scholar 

  16. Terabe, S.; Otsuka, K.; Ichikawa, K.; Tsuchiya, A.; Ando, T. (1984) Electrokinetic separations with micellar solutions and open-tubular capillaries. Anal. Chem. 56, 111–113.

    Article  CAS  Google Scholar 

  17. Ward, T.J. (1994) Chiral media for capillary electrophoresis. Anal. Chem. 66, 633A–640A.

    Article  Google Scholar 

  18. Novotny, M.; Soini, H.; Stefansson, M. (1994) Chiral separation through capillary electromigration methods. Anal. Chem. 66, 646A–655A.

    Article  CAS  Google Scholar 

  19. Bereuter, T.L. (1994) Enantioseparation by capillary electrophoresis. LC-GC 12, 748–766.

    CAS  Google Scholar 

  20. Zhu, M.D.; Hansen, D.L.; Burd, S.; Gannon, F. (1989) Factors affecting free zone electrophoresis and isoelectric focusing in capillary electrophoresis. J. Chromatogr. 480, 311–319.

    Article  CAS  Google Scholar 

  21. Bae, Y.C.; Soane, D. (1993) Polymeric separation media for electrophoresis: cross-linked systems or entangled solutions. J. Chromatogr. 652, 17–22.

    Article  CAS  Google Scholar 

  22. Dolnik, V. (1994) Capillary gel electrophoresis. J. Microcol. Sep. 6, 315–330.

    Article  CAS  Google Scholar 

  23. Hjerten, S.; Liao, J.-L.; Yao, K. (1987) Theoretical and experimental study of high-performance electrophoretic mobilization of isoelectrically focused protein zones. J. Chromatogr. 387, 127–138.

    Article  CAS  Google Scholar 

  24. Zhu, M.; Rodriguez, R.; Wehr, T. (1991) Optimizing separation parameters in capillary isoelectric focusing. J. Chromatogr. 559, 479–488.

    Article  CAS  Google Scholar 

  25. Oefner, P.; Haefele, R.; Bartsch, G.; Gunther, B. (1990) Isotachophoretic separation of organic acids in biological fluids. J. Chromatogr. 516, 251–262.

    Article  CAS  Google Scholar 

  26. Kitagawa, S.; Tsuda, T. (1994) Effects of pH and organic solvent on chromatographic behavior in capillary electrochromatography.J. Microcol. Sep. 6, 91–96.

    Article  CAS  Google Scholar 

  27. Gordon, D.B.; Lord, G.A.; Jones, D.S. (1994) Development of packed capillary column electrochromatography/mass spectrometry. Rapid Commun. Mass Spectrom. 8, 544–548.

    Article  CAS  Google Scholar 

  28. Yan, C; Schaufelberger, D.; Erni, F. (1994) Electrochromatography and micro highperformance liquid chromatography with 320 µm I.D. packed columns. J. Chromatogr. 670, 15–23.

    Article  CAS  Google Scholar 

  29. Smith, N.W.; Evans, M.B. (1994) The analysis of pharmaceutical compounds using electrochromatography. Chromatographia 38, 649–657.

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Chapman & Hall

About this chapter

Cite this chapter

Kitagishi, K. (1997). Introduction. In: Shintani, H., Polonský, J. (eds) Handbook of Capillary Electrophoresis Applications. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1561-9_1

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-1561-9_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7197-0

  • Online ISBN: 978-94-009-1561-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics