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Signaling pathways regulating ion transport in polarized cells

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Epithelial Transport

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Abstract

A critical function of polarized tissues is to generate and maintain differences in the composition of the milieu between the two compartments separated by the tissue. This is readily apparent in compartments separated by epithelial cells, endothelial cells and bone cells (highly specialized polarized cells). To generate and maintain this difference in composition between the compartments requires a regulated vectorial transport of solutes and water across the cells of these tissues. Hence, the regulation of vectorial transport is central to the function of all polarized cells.

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  1. Norman J. Karin
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  2. Min I. N. Zhang
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  3. E. Radford Decker
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  4. Roger O’Neil
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Editors and Affiliations

  1. Department of Physiology and Biophysics, University of Texas Medical Branch, 77555-0641, Galveston, Texas, USA

    Nancy K. Wills PhD , Luis Reuss MD  & Simon A. Lewis PhD ,  & 

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Karin, N.J., Zhang, M.I.N., Decker, E.R., O’Neil, R. (1996). Signaling pathways regulating ion transport in polarized cells. In: Wills, N.K., Reuss, L., Lewis, S.A. (eds) Epithelial Transport. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1495-7_12

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