Abstract
The association of gastrointestinal and lower genital tract infections and the subsequent development of arthritis has been recognized for many years. As long ago as 1818 Sir Benjamin Brodie1 described a series of patients with the condition that a century later became eponymously linked with Hans Reiter2. However, it was only in 1942 that it was suggested that the characteristic triad of non-gonococcal urethritis, poly- or monarthritis and conjunctivitis, should be regarded as a distinct clinical syndrome3. It is now well recognized that often the whole triad is not present, and patients may only display evidence of urethral discharge and arthritis; the term ‘incomplete Reiter’s syndrome’ has been used to describe such patients4 (Figure 2.1). In addition, the term ‘reactive arthritis’ is being used more frequently to describe the rheumatological features of Reiter’s syndrome, and other arthropathies associated with infections at sites distant from joints. The consideration of a diagnosis of reactive arthritis has the added advantage of alerting the physician to the possibility of an infective trigger, which in many instances may give rise to unremarkable symptoms and may antedate the joint symptoms by some weeks5.
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Allard, S.A., Maini, R.N. (1988). Reiter’s Syndrome and Reactive Arthritis. In: Wright, D.J.M. (eds) Immunology of Sexually Transmitted Diseases. Immunology and Medicine, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1255-7_2
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