Abstract
Osteoarthritis (OA) is a common systemic disorder characterized in humankind by painful, stiff, swollen joints that show cartilage loss and bony overgrowth of radiographic examination. X-rays show joint space narrowing, bony eburnation, osteophytes and bony spurs. The joint with OA is usually bony hard with irregular knobby contours and somewhat limited in motion. Cartilage loss and osteophyte formation are usually detected simultaneously but either may precede the other. The presence of these characteristic radiographic changes in the joints without clinical symptons is considered physiologic degeneration and does not warrant the diagnosis of OA which is a disorder characterized by both signs and symptoms.
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Denko, C.W. (1989). Osteoarthritis: a metabolic disorder. In: Rainsford, K.D., Velo, G.P. (eds) New Developments in Antirheumatic Therapy. Inflammation and Drug Therapy Series, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1253-3_2
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DOI: https://doi.org/10.1007/978-94-009-1253-3_2
Publisher Name: Springer, Dordrecht
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