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The Motility Defect

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Bile Acids in Health and Disease

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Abstract

The recent and very considerable expansion in our understanding of the physico-chemical factors leading to cholesterol gallstone formation has, to some extent, diverted attention from the part played by the gallbladder itself in the pathogenesis of gallstones. It was not, however, always thus. An early theory of gallstone formation which emerged in the late 19th century suggested that it was material from the gallbladder wall itself that was the focus for stone formation. A few years earlier, the simple concept that stasis of gallbladder contents might contribute to the development of gallstones was formulated. The historical development of the role of the gallbladder in gallstone pathogenesis is discussed by LaMorte et al..1 in a valuable but outdated review.

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Author information

Authors and Affiliations

  1. Department of Gastroenterology, King’s College Hospital, Denmark Hill, SE5 9RS, London, UK

    I. C. Forgacs

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  1. I. C. Forgacs
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Editors and Affiliations

  1. Department of Medicine, St. George’s Hospital Medical School, London, UK

    Tim Northfield , Riadh Jazrawi  & Patrick Zentler-Munro ,  & 

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© 1988 Kluwer Academic Publishers

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Forgacs, I.C. (1988). The Motility Defect. In: Northfield, T., Jazrawi, R., Zentler-Munro, P. (eds) Bile Acids in Health and Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1249-6_9

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  • DOI: https://doi.org/10.1007/978-94-009-1249-6_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7054-6

  • Online ISBN: 978-94-009-1249-6

  • eBook Packages: Springer Book Archive

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