Skip to main content
SpringerLink
Log in
Book cover

Bile Acids in Health and Disease pp 183–186Cite as

Cheno-versus Ursodeoxycholic Acid

  • Chapter

Abstract

Chenodeoxycholic acid (cheno) and ursodeoxycholic acid (urso) are the two agents now available for the oral dissolution of cholesterol gallstones.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Johnston, C.G. and Nakayama, F. (1957). Solubility of cholesterol and gallstones in metabolic material. Arch. Surg., 75, 436

    Google Scholar 

  2. Danzinger, R.G., Hofmann, A.F. and Shoenfield, L.J. (1972). Dissolution of cholesterol gallstones by chenodeoxycholic acid. N. Engl. J. Med., 286, 1

    Article  PubMed  CAS  Google Scholar 

  3. Makino, I. and Shginozaky, K. (1975). Dissolution of cholesterol gallstones by ursodeoxycholic acid. Jap. J. Gastroenterol., 72, 690

    CAS  Google Scholar 

  4. Roda, E., Bazzoli, F. and Labate, A.M.M. et al. (1982). Ursodeoxycholic acid vs chenodeoxycholic acid as cholesterol dissolving agents: a comparative randomised study. Hepatology, 2 804

    Article  PubMed  CAS  Google Scholar 

  5. van Berge Henegouwen, G.P. and Hofmann, A.F. (1977). Pharmacology of chenodeoxycholic acid: II Absorption and Metabolism. Gastroenterology, 73, 300

    PubMed  Google Scholar 

  6. Sama, C., La Russo, N.F. and Lopez del Pino, V. et al. (1982). Effects of bile acids administration on biliary lipid secretion in healthy volunteers. Gastroenterology, 82, 515

    PubMed  CAS  Google Scholar 

  7. Hardison, W.G.M. and Grundy, S.M. (1984). Effect of ursodeoxycholic acid and its taurine conjugate on bile acid synthesis and cholesterol absorption. Gastroenterology, 87, 130

    PubMed  CAS  Google Scholar 

  8. Coyne, M.J., Bonorris, G.G. and Goldstein, L.I. et al. (1976). Effect of chenodeoxycholic acid and phenobarbital on the rate limiting enzymes of hepatic cholesterol and bile acid synthesis in patients with gallstones. J. Lab. Clin. Med., 87, 281

    PubMed  CAS  Google Scholar 

  9. Ahlberg, J., Angelin, B. and Einarsson, K. (1981). Hepatic 3-hydroxy-3-methylglutaril Coenzyme A reductase activity and biliary lipid composition in man: relation to cholesterol gallstone disease and effects of cholic and chenodeoxycholic acid treatment. J. Lipid. Res., 22 410

    PubMed  CAS  Google Scholar 

  10. Einarsson, K. and Grundy, S.M. (1980). Effects of feeding cholic acid and chenodeoxycholic acid on cholesterol absorption and hepatic secretion of biliary lipid in man. J. Lipid. Res., 21, 23

    PubMed  CAS  Google Scholar 

  11. Salvioli, G., Igimi, H. and Carey, M.C. (1983). Cholesterol gallstone dissolution in bile. Dissolution kinetics of crystalline cholesterol monohydrate by conjugated cheno-deoxycholate-lecithin and conjugated ursodeoxycholate-lecithin mixtures: dissolution phase equilibria and dissolution mechanisms. J. Lipid. Res., 24, 701

    PubMed  CAS  Google Scholar 

  12. Shoenfield, LJ. and Lachin, J.M. (1981). The Steering Committee and The National Cooperative Gallstone Study Group. Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: The National Cooperative Gallstone Study. Ann. Intern. Med., 95, 257

    Google Scholar 

  13. Frabboni, R., Bazzoli, F. and Mazzella, G. et al. (1985). Acquired gallstone calcification during cholelitholytic treatment with chenodeoxycholic, ursodeoxycholic and taurour-sodeoxycholic acids. Hepatology, 5, 1004

    Google Scholar 

  14. Villanova, N., Bazzoli, F., Frabboni, R. et al. (1987). Gallstone recurrence after successful oral bile acid treatment: a follow up study and evaluation of postdissolution treatment. Gastroenterolgy, 92, 1789

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Istituto di Clinica Medica e Gastroenterologia, Università di Bologna, Italy

    L. Barbara, F. Bazzoli & E. Roda

Authors
  1. L. Barbara
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. Bazzoli
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Roda
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Medicine, St. George’s Hospital Medical School, London, UK

    Tim Northfield , Riadh Jazrawi  & Patrick Zentler-Munro ,  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Kluwer Academic Publishers

About this chapter

Cite this chapter

Barbara, L., Bazzoli, F., Roda, E. (1988). Cheno-versus Ursodeoxycholic Acid. In: Northfield, T., Jazrawi, R., Zentler-Munro, P. (eds) Bile Acids in Health and Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1249-6_12

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-1249-6_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7054-6

  • Online ISBN: 978-94-009-1249-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation