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Maternal Immune Responses to the Fetus in Human Pregnancy

  • Chapter
Immunology of Pregnancy and its Disorders

Part of the book series: Immunology and Medicine Series ((IMME,volume 10))

Abstract

The fetus expresses paternally derived antigens that are genetically foreign to the mother, so how does the fetal allograft survive gestation, unharmed by the maternal immune system1? In fact, the fetus has no direct contact with the maternal immune system, and it is the trophoblast of the placenta and fetal membranes which forms the interface between maternal and fetal tissues. This chapter examines the nature of maternal immune responses to the fetoplacental unit and how they are regulated.

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Authors
  1. I. L. Sargent
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  2. C. W. G. Redman
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  1. Department of Pediatrics, St Thomas’s Hospital, London, UK

    C. M. M. Stern

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Sargent, I.L., Redman, C.W.G. (1989). Maternal Immune Responses to the Fetus in Human Pregnancy. In: Stern, C.M.M. (eds) Immunology of Pregnancy and its Disorders. Immunology and Medicine Series, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1247-2_5

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