Skip to main content
SpringerLink
Log in
Book cover

Molecules in Physics, Chemistry, and Biology pp 281–297Cite as

Molecules as Signal Transmitters in Biological Systems

  • Chapter

Part of the book series: Topics in Molecular Organization and Engineering ((MOOE,volume 4))

Abstract

Some molecules are of biological importance not as components of biological structures, but rather as signal transmitters. This signalling function can tentatively be distributed into four main categories by respect to its range: information can be transferred between different points in a cell, between different cells, between different individuals or between individuals and their environment.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. G. Preti, A. B. Smith, and G. K. Beauchamp: Chemical and Behavioral Complexity in Mammalian Chemical Communication Systems (Chemical Signals in Vertebrates, Ed. D. Müller-Schwarze and M. M. Mozell), pp. 95–114, Plenum Press, New-York (1977).

    Google Scholar 

  2. D. A. Marshall, L. Blumer, and D. G. Moulton: Chem. Senses 6,445–453 (1981).

    Article  Google Scholar 

  3. D. G. Moulton: Physiol. Rev. 56, 578–593 (1976).

    CAS  Google Scholar 

  4. A. Holley and P. MacLeod: J. Physiol. (Paris) 73, 725–828 (1977).

    CAS  Google Scholar 

  5. A. Schilling:Olfactory Communication in Prosimians (The Study of Prosimian Behavior, Ed. G. A. Doyle and R. D. Martin), pp. 461–538, Academic Press, New-York (1979).

    Google Scholar 

  6. H. Zwaardemaker: Die Physiologie des Geruchs, Engelman, Leipzig (1895).

    Google Scholar 

  7. D. Tucker: J. Gen. Physiol. 46,453–489 (1963).

    Article  CAS  Google Scholar 

  8. D. G. Laing: Perception 12, 99–117 (1983).

    Article  CAS  Google Scholar 

  9. P. Laffort, F. G. Patte, and M. Etcheto:Ann. NY Acad. Sci. 237,193–208 (1974).

    Article  CAS  Google Scholar 

  10. J. Caprio: High Sensitivity and Specificity of Olfactory and Gustatory Receptors of Catfish to Aminoacids (Chemoreception in Fishes, Ed. T. J. Hara), pp. 109–134, Elsevier (1982).

    Google Scholar 

  11. K. B. Döving, R. Selset, and G. Thommesen: Acta Physiol Scand. 108, 123–131 (1980).

    Article  Google Scholar 

  12. J. W. Atz: Qu. Rev. Biol. 27, 366–376 (1952).

    Article  CAS  Google Scholar 

  13. K. B. Döving, M. Dubois-Dauphin, A. Holley, and F. Jourdan: Acta Zool. (Stockholm) 58, 245–255 (1977).

    Article  Google Scholar 

  14. P. MacLeod: La formation d’une image chimiosensorielle (L’Aube des Sens, Ed. E. Herbinet and M. C. Busnel), pp. 345–356, Stock, Paris (1981).

    Google Scholar 

  15. J. Marco, H. Morera, and J. A. Gimenez: Acta Otolaryngol 46,114–126 (1956).

    Article  CAS  Google Scholar 

  16. T. Kubo, K. Fukuda, A. Mikami, A. Maeda, H. Takahashi, M. Haga, T. Haga, A. Ishiyama, K. Kangawa, M. Kojima, H. Matsuo, T. Hirose, and S. Numa: Nature 323, 411–416 (1986).

    Article  CAS  Google Scholar 

  17. A. Danchin: La Recherche 18, 262–264 (1987).

    Google Scholar 

  18. Z. W. Hall:Trends Neurosci. 10, 99–101 (1987).

    Article  CAS  Google Scholar 

  19. A. C. Dolphin:Trends Neurosci. 10, 53–57 (1987).

    Article  CAS  Google Scholar 

  20. J. L. Popot and J. P. Changeux: Physiol Rev. 64,1162–1239 (1984).

    CAS  Google Scholar 

  21. A. Brisson and P. N. T. Unwin: Nature 315,474–477 (1985).

    Article  CAS  Google Scholar 

  22. D. Colquhoun and B. Sackman:J. Physiol. (London) 369, 501–557 (1985).

    CAS  Google Scholar 

  23. D. E. Koshland: Physiol Rev. 59, 812–862 (1979).

    Google Scholar 

  24. D. E. Koshland: Bacterial Chemotaxis as a Model Behavioral System, Raven Press (1980).

    Google Scholar 

  25. G. L. Hazelbauer and J. Adler: Nature New Biol 30,101–104 (1971).

    Google Scholar 

  26. G. L. Hazelbauer:J. Bacteriol. 122, 206–214 (1975).

    CAS  Google Scholar 

  27. R. Aksamit and D. E. Koshland: Biochemistry 13,4473–4478 (1974).

    Article  CAS  Google Scholar 

  28. R. W. Reader, W. Tso, M. Springer, S. Goy, and J. Adler: J. Gen. Microbiol. 111, 363–374 (1978).

    Google Scholar 

  29. D. E. Koshland: Ann. Rev. Biochem. 50, 765–782 (1981).

    Article  CAS  Google Scholar 

  30. K. E. Kaissling: Molecular Recognition (Biophysics, Ed. W. Hoppe, W. Lohman, H. Markl, and H. Ziegler), pp. 697–709, Springer-Verlag, Heidelberg (1983).

    Google Scholar 

  31. A. Holley, A. Duchamp, M. F. Revial, A. Juge, and P. MacLeod: Ann. NY Acad. Sci. 237, 102–114(1974).

    Article  CAS  Google Scholar 

  32. A. Duchamp and G. Sicard:Chem. Senses 8, 355–366 (1984).

    Article  Google Scholar 

  33. J. E. Amoore, L. Forrester, and P. Pelosi: Chem. Senses Flav. 2,17–25 (1976).

    Article  CAS  Google Scholar 

  34. J. E. Amoore:Chem. Senses Flav. 2,267–281 (1977).

    Article  CAS  Google Scholar 

  35. Z. Chen and D. Lancet:Proc. Natl Acad. Sci. USA 81,1859 (1984).

    Article  CAS  Google Scholar 

  36. U. Pace, E. Hanski, Y. Salomon, and D. Lancet: Nature 316, 255–258 (1985).

    Article  CAS  Google Scholar 

  37. D. Lancet: Ann. Rev. Neurosci. 9, 329–355 (1986).

    Article  CAS  Google Scholar 

  38. C. Pfaffmann:Chem. Senses Flav. 1, 61–67 (1974).

    Article  Google Scholar 

  39. A. Faurion, S. Saito, and P. MacLeod:Chem. Senses 5,107–121 (1980).

    Article  CAS  Google Scholar 

  40. S. S. Schiffman and R. P. Erickson: Neurosci. Behav. 2,109–117 (1980).

    Article  Google Scholar 

  41. R. P. Erickson:Definitions: a Matter of Taste (Taste, Olfaction, and the Central Nervous System, Ed. D. W. Pfaff), pp. 129–150, The Rockefeller University Press, New-York (1985).

    Google Scholar 

  42. S. S. Schiffman, E. Lockhead, and F. W. Maes: Proc. Natl Acad. Sci. USA 80, 6136–6140 (1983).

    Article  CAS  Google Scholar 

  43. C. M. Christensen and D. Malamud:Chem. Senses 10,454 (1985).

    Google Scholar 

  44. A. Faurion and P. MacLeod: Sweet Taste Receptor Mechanisms (Nutritive Sweeteners, Ed. G. G. Birch and K. J. Parker), pp. 247–273, Applied Science Publishers, London (1982).

    Google Scholar 

  45. A. Faurion: MSG as one of the Sensitivities Among a Continuous Taste Space (Umami: a Basic Taste, Ed. Y. Kawamura and M. R. Kare), pp. 387–408, Marcel Dekker, New-York (1987).

    Google Scholar 

  46. A. L. Fox:Proc. Natl Acad. Sei. USA 18,115–120 (1932).

    Article  CAS  Google Scholar 

  47. H. Kalmus: Ann. Hum. Genet. 22,222–230 (1958).

    Article  CAS  Google Scholar 

  48. R. H. Cagan and A. G. Boyle: Biochim. Biophys. Acta 799,230–237 (1984).

    CAS  Google Scholar 

  49. E. Neher and B. Sackman:Nature 260,779–802 (1976).

    Article  Google Scholar 

  50. A. M. Spiegel, P. Gierschik, M. A. Levine, and R. W. Downs: New Engl J. Med. 312, 26–33 (1985).

    Article  CAS  Google Scholar 

  51. M. J. Berridge:Sei. Am. 235,142–151 (1985).

    Google Scholar 

  52. D. Ottoson and G. M. Shepherd: Cold Spring Harb. Symp. Quant. Biol. 30,105–114 (1965).

    CAS  Google Scholar 

  53. B. Hille: Ionic Channels of Excitable Membranes, Sinauer, Sunderland, Mass., USA (1984).

    Google Scholar 

  54. B. Sackmann and E. Neher: Ed. Single-Channel Recording, Plenum Press, New-York (1983).

    Google Scholar 

  55. D. Trotier and P. MacLeod: Brain Res. 268, 225–237 (1983).

    Article  Google Scholar 

  56. D. Trotier: Pflüg. Arch. 407, 589–595 (1986).

    Article  CAS  Google Scholar 

  57. T. Nakamura and G. H. Gold:Nature 325, 442–444 (1987).

    Article  CAS  Google Scholar 

  58. J. Dudel: Excitation, Conduction and Synaptic Transmission (Biophysics, Ed. W. Hoppe, W. Lohmann, H. Markl, and H. Ziegler), pp. 641–657, Springer-Verlag, Heidelberg (1983).

    Google Scholar 

  59. R. Horn: Gating of Channels in Nerve and Muscle (Ion Channels: Molecular and Physiological Aspects, Ed. W. D. Stein), pp. 53–97, Academic Press, New-York (1984).

    Google Scholar 

  60. L. Cantley: Trends Neurosci. 9,1–3 (1986).

    Article  CAS  Google Scholar 

  61. A. L. Hodgkin and A. F. Huxley: J. Physiol. (London) 117,500–544 (1952).

    CAS  Google Scholar 

  62. R. H. Harper:Human Senses in Action, Churchill-Livingstone, Edinburgh (1972).

    Google Scholar 

  63. R. S. Johansson and A. B. Vallbo: J. Physiol. (London) 286, 283–300 (1979).

    CAS  Google Scholar 

  64. H. Diamant, B. Oakley, L. Ström, C. Wells, and Y. Zotterman: Acta Physiol. Scand. 64, 67–74 (1965).

    Article  CAS  Google Scholar 

  65. B. Oakley: Chem. Senses 10,469–481 (1985).

    Article  CAS  Google Scholar 

  66. M. F. Revial, G. Sicard, A. Duchamp, and A. Holley:Chem. Senses 8,179–190 (1983).

    Article  Google Scholar 

  67. E. H. Polak:J. Theor. Biol. 40,469–484 (1984).

    Article  Google Scholar 

  68. J. Kauer: Coding in the Olfactory System (Neurobiology of Taste and Smell, Ed. T. E. Finger), pp. 205–231, Wiley, New-York (1987).

    Google Scholar 

  69. R. P. Erickson:Sensory Neural Patterns and Gustation (Olfaction and Taste I, Ed. Y. Zotterman), pp. 205–213, Pergamon Press, New-York (1963).

    Google Scholar 

  70. L. C. Skeen:Brain Res. 124,147–153 (1977).

    Article  CAS  Google Scholar 

  71. M. Verrier, I. Giachetti, J. Leveteau, and P. MacLeod: C.R. Acad. Sei. (Paris) 286, 1293–1296 (1978).

    CAS  Google Scholar 

  72. F. Jourdan, A. Duveau, L. Astic, and A. Holley: Brain Res. 188,139–154 (1980).

    Article  CAS  Google Scholar 

  73. D. Lancet, C. A. Greer, J. S. Kauer, and G. Shepherd: Proc. Natl. Acad. Sei. USA 79, 670–674 (1982).

    Article  CAS  Google Scholar 

  74. L. Astic and D. Saucier:Dev. Brain Res. 2, 243–256 (1982).

    Article  Google Scholar 

  75. E. T. Rolls and B. J. Rolls: Activity of Neurones in Sensory, and Motor Areas during Feeding in the Monkey (Food Intake and Chemical Senses, Ed. Y. Katsuki, M. Sato, S. Takagi, and Y. Oomura), pp. 525–550, Japan Scientific Societies Press (1977).

    Google Scholar 

  76. M. Cabanac: Qu. Rev. Biol. 54, 1–29 (1979).

    Article  CAS  Google Scholar 

  77. J. Leveteau, P. MacLeod, and G. Daval:Physiol Behav. 4,479–482 (1969).

    Article  Google Scholar 

  78. J. Le Magnen:Prog. Physiol. Psychol., 4 203–261 (1971).

    Google Scholar 

  79. J. Pager and J. P. Royet: J. Comp. Physiol. Psychol. 90, 67–77 (1976).

    Article  CAS  Google Scholar 

  80. W. J. Freeman and W. Schneider: Psychophysiol. 19,44–56 (1982).

    Article  CAS  Google Scholar 

  81. M. Yoshida: Chem. Senses Flav. 1,443–464 (1975).

    Article  Google Scholar 

  82. P. Claverie: Elaboration of Approximate Formulae for the Interaction between Large Molecules (Intermolecular Interactions: from Diatomics to Biopolymers, Ed. B. Pullman), pp. 69–305, Wiley, New-York (1978)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Neurobiologie Sensorielle de I’E.P.H.E. et GRECO ‘Sens Chimiques’ du C.N.R.S, 1, Avenue des Olympiades, 91305, Massy, France

    P. Macleod

Authors
  1. P. Macleod
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Centre de Mécanique Ondulatoire Appliquée, Laboratoire de Chimie Physique, CNRS and University of Paris, France

    Jean Maruani

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Kluwer Academic Publishers, Dordrecht, The Netherlands.

About this chapter

Cite this chapter

Macleod, P. (1989). Molecules as Signal Transmitters in Biological Systems. In: Maruani, J. (eds) Molecules in Physics, Chemistry, and Biology. Topics in Molecular Organization and Engineering, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1173-4_12

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-1173-4_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-277-2599-8

  • Online ISBN: 978-94-009-1173-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation