Abstract
The head and neck region can be host to a great variety of tumors. In fact with the exception of those arising from the reproductive system, every type of neoplastic growth has its representative in this area. Carcinomas can arise from skin and mucosal surfaces, contained in the cephalic region. The sarcoma family is represented by tumors from all mesenchymal cell types (17), including connective tissue and its derivatives, endothelial tissue, lymphoid and both striated and smooth muscular tissue. Tumors from glial and nervous cells are present as well. Adipose tissue is less abundant and lipomas are less frequent in the oropharyngeal region than in the extremities and the retroperitoneum (42, 43, 62, 107, 113, 115, 124, 204), but Fu and Perzin (63) described a nasopharyngeal liposarcoma and recently a myxoid liposarcoma has been seen by Gaia and Coll. (143) confirming the presence of tumors of all tissue types in the cephalic region. The cephalic region harbors also several peculiar types of tissue. The teeth are formed by both an epithelial element, the ameloblasts, and mesenchymal elements, such as the odontoblasts, cementoblasts and fibroblasts. The former are only transient cells in the odontogenesis of the human, different from the rodents, where the continuously growing incisor teeth are maintained by a vital ameloblastic population. Neoplastic growth from both the ameloblast and the odontoblast has been described, sometimes as mixed odontogenic tumors (217). Ameloblastic growth is thought to derive from islets of less differentiated cells in the periodontal spaces, that are embryonic remnants of the epithelial sheet of the enamel organ, while the odontoblastic component may derive from fibroblasts exposed to cells of the early amelogenic epithelium of the dental lamina. Neoplasms can also arise from cell remnants of another transient organ present in the rhinopharynx, the chorda, and are called chordomas.
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Broich, G. (1989). Comparison of the Progression of Selected, Topographically Particular, Tumors in the Head and Neck Region. In: Brunson, K.W. (eds) Local Invasion and Spread of Cancer. Cancer Growth and Progression, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1093-5_2
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