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Local Invasion and Spread of Cancer pp 148–153Cite as

Neoplastic Progression of the Myeloid Leukemias

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Part of the book series: Cancer Growth and Progression ((CAGP,volume 7))

Abstract

The expression, neoplastic progression, refers to the evolution of neoplastic cells from a less to a more malignant state. This evolutionary process is associated with increasing refractoriness to therapy, increasing metastatic potential,and usually a decrease in the level of differentiation of the neoplasm. Karyotypic evolution is often recognized during this process. The key(s) to understanding neoplastic diseases and hence the key to their control, probably is to be found within this process. We have been studying neoplastic progression in the myeloid leukemias and what follows is a discussion of our concepts of this process.

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Authors
  1. H. D. Preisler
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  2. A. Raza
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Editors and Affiliations

  1. Department of Immunology and Infectious Diseases, Pfizer Central Research, Groton, Conn., USA

    Kenneth W. Brunson

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© 1989 Kluwer Academic Publishers

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Preisler, H.D., Raza, A. (1989). Neoplastic Progression of the Myeloid Leukemias. In: Brunson, K.W. (eds) Local Invasion and Spread of Cancer. Cancer Growth and Progression, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1093-5_11

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  • DOI: https://doi.org/10.1007/978-94-009-1093-5_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6982-3

  • Online ISBN: 978-94-009-1093-5

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