Abstract
Primary infection with varicella zoster virus (VZV) results in the common childhood illness varicella or chickenpox. However, in common with other members of the herpesvirus family, VZV is not completely eliminated from the body following recovery from the primary infection, and enters into a latent state. After a period of time, which is usually decades, the virus reactivates and produces the recurrent illness herpes zoster (or shingles).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Grose, C. (1981). Variation on a theme by Fenner: the pathogenesis of chickenpox. Pediatrics, 68, 735–7
Triebwasser, J. H., Harris, R. E. and Rhoades, E. R. (1967). Varicella pneumonia in adults: Report of seven cases and a review of the literature. Medicine, 46, 409–23
Johnson, R. and Milbourn, P. E. (1970). Central nervous system manifestations of chickenpox. Can. Med. Assoc. J., 102, 831–4
Heath, R. B. (1987). Varicella-zoster. In Zuckerman, A. J. et al. (eds), Principles and Practice of Clinical Virology, p. 58. (Chichester: John Wiley & Sons)
Hanshaw, J. B. and Dudgeon, J. A. (1978). Varicella-zoster infections. In Viral Diseases of the Fetus and Newborn, pp. 192–208. (Philadelphia: W. B. Saunders)
Feldman, S., Hughes, W. T. and Daniel, C. B. (1975). Varicella in children with cancer: seventy-seven cases. Pediatrics, 56, 388–97
Izawa, T., Ihara, T., Hattori, A., Iwaza, T., Kamiya, H., Sakurai, M. and Takahashi, M. (1977). Application of a live varicella vaccine in children with acute leukaemia or other malignant diseases. Pediatrics, 60, 805–9
Joseph, C. A. and Noah, N. D. (1988). Epidemiology of chickenpox in England and Wales, 1967–85. Br. Med. J., 296, 673–6
Takahashi, M., Otsuka, T., Okuna, Y., Yazaki, T. and Isomura, S. (1974). Live vaccine to prevent the spread of varicella in children in hospital. Lancet, 2, 1288–90
Asano, Y., Nakayama, H., Yazaki, T., Ito, S., Isomura, S. and Takahashi, M. (1977). Protective efficacy of vaccination in children in four episodes of natural varicella and zoster in the ward. Pediatrics, 59, 8–12
Asano, Y., Nakayama, H., Yazaki, T., Kato, R., Hirose, S., Tsuzuki, K., Ito, S., Isomura, S. and Takahashi, M. (1977). Protection against varicella in family contacts by immediate inoculation with live varicella vaccine. Pediatrics, 59, 3–7
Asano, Y. and Takahashi, M. (1977). Clinical and serological testing of a live varicella vaccine and two-year follow-up for immunity of the vaccinated children. Pediatrics, 60, 810–14
Bogger-Goren, S., Baba, K., Hurley, P., Yabuuchi, M., Takahashi, M. and Ogra, P. L. (1982). Antibody response to varicella-zoster virus after natural or vaccine-induced infection. J. Infect. Dis., 146, 260–5
Arbeter, A. M, Star, S. E., Weibel, R. E. and Plotkin, S. A. (1986). Varicella vaccine studies in healthy children and adults. Pediatrics, 78, 748–56
Ndumbe, P. M., Cradock-Watson, J. E., Heath, R. B. and Levinsky, R. J. (1985). Live varicella immunization in healthy non-immune nurses. Postgrad. Med. J., 61, 133–5
Gershon, A. A., Steinberg, S. P., LaRussa, P., Ferrara, A., Hammerschlag, M., Gelb, L. and the NIAID Varicella Vaccine Collaborative Study Group. (1988). Immunization of healthy adults with live attenuated varicella vaccine. J. Infect. Dis., 158, 132–7
Weibel, R. E., Neff, B. J., Kuter, B. J., Guess, H. A., Rothenberger, C. A., Fitzgerald, A. J., Connor, K. A., McLean, A. A., Hilleman, M. R., Buynak, E. B. and Scolnick, E. M. (1984). Live attenuated varicella virus vaccine. N. Engl. J. Med., 310, 1409–15
Andre, F. E. (1985). Worldwide experience with the Oka-strain live varicella vaccine. Postgrad. Med. J., 61, 113–20
Takahashi, M., Kamiya, H., Baba, K., Asano, Y., Ozaki, T. and Horiuchi, K. (1985). Clinical experience with Oka live varicella vaccine in Japan. Postgrad. Med. J., 61, 61–7
Gershon, A. A., Steinberg, S. P., Gelb, L. and the National Institute of Allergy and Infectious Diseases Varicella Vaccine Collaborative Study Group (1986). Live attenuated varicella vaccine use in immunocompromised children and adults. Pediatrics, 78, 757–62
Heath, R. B., Malpas, J. S., Kangro, H. O., Ward, A., McEniery, J. M. and Kingston, J. E. (1987). Efficacy of varicella vaccine in patients with solid tumours. Arch. Dis. Child, 62, 569–72
Shiraki, K., Yamanishi, K. and Takahashi, M. (1984). Susceptibility to acyclovir of oka-strain varicella vaccine and vaccine-derived viruses isolated from immunocompromised patients. J. Infect. Dis., 150, 306–7
Hayakawa, Y., Torigoe, S., Shiraki, K., Yamanishi, K. and Takahashi, M. (1984). Biologic and biophysical markers of live varicella vaccine strain (Oka): identification of clinial isolates from vaccine recipients. J. Infect. Dis., 149, 956–63
Lawrence, R., Gershon, A. A., Holzman, R., Steinberg, S. P. and the NIAID Varicella Vaccine Collaborative Study Group (1988). The risk of zoster after varicella vaccination in children with leukaemia. N. Engl. J. Med., 318, 543–8
Ross, A. H., Lencher, E. and Reitman, G. (1962). Modification of chickenpox in family contacts by administration of gamma globulin. N. Engl. J. Med., 267, 369–76
Preblud, S. R. (1986). Varicella: complications and costs. Pediatrics, 78, 728–35
Brunell, P. A., Novelli, V. M., Lipton, S. V. and Pollock, B. (1988). Combined vaccine against measles, mumps, rubella and varicella. Pediatrics, 81, 779–84
Berger, R., Luescher, D. and Just, M. (1984). Enhancement of varicella-zoster-specific immune responses in the elderly by boosting with varicella vaccine. J. Infect. Dis., 149, 647
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Kluwer Academic Publishers
About this chapter
Cite this chapter
Heath, R.B. (1989). Varicella vaccines. In: Zuckerman, A.J. (eds) Recent Developments in Prophylactic Immunization. Immunology and Medicine, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1067-6_6
Download citation
DOI: https://doi.org/10.1007/978-94-009-1067-6_6
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6969-4
Online ISBN: 978-94-009-1067-6
eBook Packages: Springer Book Archive