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Comparison of BoLa Class I and Class II Typing Methods and their Application to MHC Function Studies

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Book cover Improving Genetic Disease Resistance in Farm Animals

Part of the book series: Current Topics in Veterinary Medicine and Animal Science ((CTVM,volume 52))

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Abstract

The organisation of the bovine MHC has been investigated by Southern blot analysis using bovine class I and human class II cDNA probes. It is likely that there are multiple class I loci, although only the product of one locus has been identified serologically. The class II region is complex, possibly with similar organisation to the human class II region except that the DP sub-region may be missing. Only DR like products have been identified so far using cross-reactive monoclonal antibodies.

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© 1989 ECSC,EAEC,Brussels and Luxembourg

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Williams, J.L., Brown, P., Glass, E.J., Oliver, R.A., Spooner, R.L. (1989). Comparison of BoLa Class I and Class II Typing Methods and their Application to MHC Function Studies. In: Improving Genetic Disease Resistance in Farm Animals. Current Topics in Veterinary Medicine and Animal Science, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1057-7_9

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  • DOI: https://doi.org/10.1007/978-94-009-1057-7_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6967-0

  • Online ISBN: 978-94-009-1057-7

  • eBook Packages: Springer Book Archive

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