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The Chicken MHC and its Importance+

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Part of the book series: Current Topics in Veterinary Medicine and Animal Science ((CTVM,volume 52))

Abstract

MHC (B-complex) typing in chickens is usually done by haemagglutination which has the undisputed advantage of speed and ease, but also carries pitfalls that can lead to great confusion. Standard test sera in general use are nearly all defining B-haplotypes of White Leghorn and are not adequate for testing of other races, as exemplified by their use in heavy races used in the production of broilers. A development of alloantisera for typing of White Plymouth Rock and White Cornish is described. A brief review is given of recent work relating genetic disease resistance in chickens to its B-complex.

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References

  • Briles, W.E., Stone, H.A., and Cole, R.K. 1977. Marek’s disease: Effects of B histocompatibility alloalleles in resistant and susceptible chicken lines. Science, 195, 193 – 195.

    Google Scholar 

  • Briles, W.E., Bumstead, N., Ewert, D.L., Gilmour, D.G., Gogusev, J., Hala, K., Koch, C., Longenecker, B.M., Nordskog, A.W., Pink, J.R.L., Schierman, L.W., Simonsen, M., Toivanen, A., Toivanen, P., Vainio, O., and Wick, G. 1982. Nomenclature for chicken Major Histocompatibility (B) Complex. Immunogenetics 15: 441- 447.

    Google Scholar 

  • Briles, W.E., Briles, R., Pollock, D.L., and Pattison, M. 1982a. Marek’s disease resistance of B (MHC) heterozygotes in a cross of purebred Leghorn lines. Poultry Sc., 61205 - 211.

    Google Scholar 

  • Briles, W.E., Briles, R., Taffs, R.E., and Stone, H.E. 1983. Resistence to a malignant lymphoma in chickens is mapped to subregion of major histocompatibility (B) complex. Science, 137, 620.

    Google Scholar 

  • Crone, M., and Simonsen, M. 1987. Avian major histocompatibility complex. In “Avian Immunology: Basis and Practice”. (Eds. A. Toivanen and P. Toivanen ). ( CRC Press, Boca Raton, Florida). Vol. II, pp. 25 - 41.

    Google Scholar 

  • Gavora, J.S., Simonsen, M., Spencer, J.L., Fairfull, R.W., and Gowe, R.S. 1986. Changes in the frequency of major histocompatibility haplotypes in chickens under selection for both high egg production and resistance to Marek’s disease. Zeitschrift fur Tierzüchtung und Züchtungsbiologie, 103, 218 - 226.

    Google Scholar 

  • Hala, K., Vilhelmova, M., and Hartmannova, J. 1976. Probable crossing-over in the B blood group system of chickens. Immunogenetics, 3, 97 - 103.

    Google Scholar 

  • Hansen, M.P., Van Zandt, J.N., and Law, G.R.J. 1967. Differences in susceptibility to Marek’s disease in chickens carrying two different B blood group alleles. Poultry Sci., 461268.

    Google Scholar 

  • Hartmann, W., Hala, K., Heil, G., and Krieg, R. 1986. Effect of B blood group genotypes on resistance to Marek’s disease in Leghorn crosses. In 7th European Poultry Conference, Paris, 24-26 August 1986. Worldfs Poultry Science Association, Branche Francaise. Vol. 1, pp 216- 220.

    Google Scholar 

  • Hutt, F.B. 1949. Genetics of the Fowl. McCraw-Hill Book Co. New York.

    Google Scholar 

  • Koch, C., Skjødt, K., Toivanen, A., and Toivanen, P. 1983. New recombinants within the MHC (B-complex) of the chicken. Tissue Antigens, 21, 129 - 137.

    Google Scholar 

  • Lamont, S.J., Bolin, C., and Cheville, N. 1987. Genetic resistance to fowl cholera is linked to the major histocompatibility complex. Immunogenetics, 25, 284 - 289.

    Google Scholar 

  • Pink, J.R.L., Droege, W., Hala, K., Miggiano, V.C., and Ziegler, A. 1977. A tree-locus model for the chicken major histocompatibility complex. Immunogenetics, 5, 203- 216.

    Google Scholar 

  • Simonsen, M., Hala, K., and Nicolaisen, E.M. 1980. Linkage disequilibrium of MHC genes in the chicken. The B-F and B-G loci. Immunogenetics, 10, 103 - 112.

    Google Scholar 

  • Simonsen, M., Crone, M., Koch, C., and Hala, K. 1982. The MHC haplotypes of the chicken. Immunogenetics, 16, 513 - 532.

    Google Scholar 

  • Simonsen, M., Kolstad, N., Edfors-Lilja, J., Liljedahl, L.-E., and Sørensen, P. 1982a. Major histocompatibility genes in egg-laying hens. Am.J.Reproduct.Immunol. 2, 148 - 152.

    Google Scholar 

  • Simonsen, M. 1988. The MHC of the chicken, genomic structure, gene products, and resistance to oncogenic DNA and RNA viruses. In “Veterinary Immunology” (Eds. B.N. Wilkie and P.E. Shewen ). ( Elsevier, Amsterdam ), pp. 243 - 253.

    Google Scholar 

  • Spencer, J.L. 1984. Progress towards eradication of lymphoid leukosis viruses - A review. Avian Path., 13, 599 - 619.

    Google Scholar 

  • Skjødt, K., Koch, C., Crone, M., and Simonsen, M. 1985. Analysis of chickens for recombination within the MHC (B- complex). Tissue Antigens, 25, 278 - 282.

    Google Scholar 

  • Sørensen, P. 1986. Studium af effekten af selektion for vaekst hos slagtekyllinger (With English summary and subtitles). (Landhusholdningsselskabets forlag, Rolighedsvej 26, DK- 1958 Frederiksberg C., Denmark ), pp. 1 - 314.

    Google Scholar 

  • Todd, J.A., Bell, J.I., and McDevitt, H.O. 1987. HLA-DQβgene contributes to susceptibility and resistance to insulin- dependent diabetes mellitus. Nature, 329, 599 - 604.

    Google Scholar 

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© 1989 ECSC,EAEC,Brussels and Luxembourg

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Simonsen, M., Arnul, M., Sørensen, P. (1989). The Chicken MHC and its Importance+ . In: Improving Genetic Disease Resistance in Farm Animals. Current Topics in Veterinary Medicine and Animal Science, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1057-7_6

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  • DOI: https://doi.org/10.1007/978-94-009-1057-7_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6967-0

  • Online ISBN: 978-94-009-1057-7

  • eBook Packages: Springer Book Archive

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