Abstract
Knowledge about the overall organization of the SLA complex, the major histocompatibility complex (MHC) in pig, has greatly progressed in recent years thanks to direct gene mapping, to gene cloning and to the study of restriction fragment length polymorphism (RFLP).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Chardon, P., Renard, Ch., and Vaiman, M. 1981. Characterization of class II histocompatibility antigens in pigs. Anim. Blood Grps. and Biochem. Genet. 12, 59 – 65.
Chardon, P., Vaiman. M., Kirszenbaum, M., Geffrotin, Cl., Renard. Ch. and Cohen, D. 1985. Restriction fragment length polymorphism of the major histocompatibility complex of the pig.Immunogenetics 21,161–171.
Chardon, P., Renard. Ch., Kirszenbaum, M., Geffrotin, Cl., Cohen, D. and Vaiman, M. 1985. Molecular genetic analyses of the major histocompatibility complex in pig families and recombinants.J.Ot Immunol. 12, 139–149.
Dolf, G.J., Stranzinger, G. 1986. Pig gene mapping assignment of the genes for mannosepnosphate isomerase (MPI) and nucleoside phosphorylase (NP) to chromosome no.7. Genet. Sel. Evol. 18, 375 – 384
Ehrlich, R.. Lifshitz, R., Pescovitz, M.D., Rudikoff, S. and Singer. D.S. 1987. Tissue-specific expression and structure of a divergent member of a class I MHC gene family. J. of Immunol. 139, 593 – 602.
frels, W.I.. Bluestone, J.A.. Hodes, R.J., Capecchi, M.R. and Singer, D.S. 1985. Expression of a microinjected porcine class I major histocompatibility complex gene in transgenic mice. Sciences. 228, 577 – 580.
Geffrotin, Cl. Popescu, C.P.. Cribiu, E.P., Boscher. J..Renard, CH., Chardon, P. and Vaiman, M. 1984. Assignment of MHC in swine to chromosome 7 by in situ nybridizaion and serological typing. Annales de genetique 27, 213 – 219.
Hruban, V., Simon, M., Hradeckv, J. and Jilek, F. 1976. Linkage of the pig main histocompatibility complex and J. blood group system. Tissue Antigens 7, 267 – 271.
Kirszenbaum, M., Renard, Ch.. Chardon, P., and Vaiman, M. 1985. Evidence for mapping pig C4 gene(s) within the pig major histocompatibility complex (SLA). Anim. Blood Grps. and Biochem. Genet. 1665–68.
Lie, W.R., Rothschild, M., and Warner, C.M. 1985. Quantitative differences in GLO enzyme levels associated with the MHC of miniature swine. Anim. Blood Grps and Biochm. Genet. 16, 243 – 248.
Lie.W-R., Rothschild,M.F., Warner, C.M. 1987. Mapping of C2,Bf,and C4 genes to the swine Major Histocompatibility Complex (Swine Leukocyte Antigen). J. Immunol 139, 3388 – 3395.
Osborne. B.A., Lunney, J.K., Pennington, L., Sachs, D.H.,and Rudikoff,S. 1983. Two-Dimensional gel analysis of swine histocompatibility antigens. J. of Immunol. 31, 2939 – 2944.
Rabin, M., Fries, R., Singer, D., and Ruddle F.H. 1985. Assignment of the porcine major histocompatibility complex to chromosome 7 by in situ hybridization. Cytogenet. Cell. Genet. 39, 206 – 209.
Sachs, D.H., Germana, S., El-Gamil, M.,Gustafsson, K., Hirsch, F., and Pratt, K. 1988. Class II genes of miniature swine.I. Class II gene characterization by RFLP and by isolation from a genomic library. Immunogenetics28, 22 – 29.
Satz, L.M., Wang,L-C., Singer,D.S.,Rudikoff,S. 1985. Stucture and expression of two porcine genomic clones encoding class I MHC antigens. J. Immunol.135, 2167 – 2175.
Singer, D.S.. Camerini-otero. R.S., Satz, M.L., Osborne, B., Sachs, D., and Rudikoff, S. 1982. Characterization of a porcine genomic clone encoding a maj[or histocompatibility antigen: expression in mouse L cells. Proc. Natl. Acad. Sci. USA.79, 1403 – 1407.
Singer, D.S.. Camerini-otero. R.S., Satz, M.L., Osborne, B., Sachs, D., and Rudikoff, S. 1982. Characterization of a porcine genomic clone encoding a maj[or histocompatibility antigen: expression in mouse L cells. Proc. Natl. Acad. Sci. USA.79, 1403 – 1407.
Vaiman, M., Chardon, P., and Renard, Ch. 1979. Genetic organization of the pig SLA complex. Studies on Nine recombinants and biochemical and lysostrip analysis. Immunogenetics 9, 353 – 361.
Vaiman, M., Hauptmann, G., Mayer, S 1978. Influence of the major histocompatibility complex in the pig (SLA) on serum haemolytic complement levels. J.Immunogenet. 5, 59 – 65.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1989 ECSC,EAEC,Brussels and Luxembourg
About this chapter
Cite this chapter
Chardon, P. (1989). The Molecular Genetics of the Sla Complex. In: Improving Genetic Disease Resistance in Farm Animals. Current Topics in Veterinary Medicine and Animal Science, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1057-7_10
Download citation
DOI: https://doi.org/10.1007/978-94-009-1057-7_10
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6967-0
Online ISBN: 978-94-009-1057-7
eBook Packages: Springer Book Archive