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Atherosclerotic hypertension

Systolic hypertension and arterial compliance in patients with arteriosclerosis obliterans of the lower limbs

  • Chapter
The Heart in Hypertension

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 98))

Abstract

Arteriosclerosis obliterans usually denotes a degenerative arteriopathy of the aorta, and of the extremities and the aortic branches that go to them [1]. It is characterized by occlusive lesions, primarily atheromatous but often accompanied by fibrosis and calcification of the tunica media. They may be associated with a varying degree of thrombosis. In the past, arteriosclerosis obliterans has been considered to be an occlusive arterial disease, exclusively or predominantly affecting the lower limbs. However, recent studies have shown that lesions affecting a significant part of the large artery system, as observed in arteriosclerosis obliterans of the lower limbs (AOLL), may have general consequences for overall circulatory dynamics [2–3] for several reasons. First, large arteries act as a reservoir that stores blood during cardiac ejection and releases it during diastole, enabling the intermittent cardiac output to be converted to a steady flow through the capillaries [4] and thus participating to the general cardiovascular homeostasis. Second, an elevated incidence of systolic hypertension is observed in patients with arteriosclerosis obliterans of the lower limbs.

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Authors
  1. Michel E. Safar
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Editors and Affiliations

  1. Department of Internal Medicine and Hypertension Research Center, Broussais Hospital, Paris, France

    M. E. Safar

  2. Cleveland Clinic Foundation, Cleveland, Ohio, USA

    F. Fouad-Tarazi

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© 1989 Kluwer Academic Publishers

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Safar, M.E. (1989). Atherosclerotic hypertension. In: Safar, M.E., Fouad-Tarazi, F. (eds) The Heart in Hypertension. Developments in Cardiovascular Medicine, vol 98. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0941-0_12

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  • DOI: https://doi.org/10.1007/978-94-009-0941-0_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6913-7

  • Online ISBN: 978-94-009-0941-0

  • eBook Packages: Springer Book Archive

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