Abstract
As suggested in the previous chapter, the process of method development does not end when enantiomeric resolution is obtained. In almost every case, a further fine-tuning of experimental variables will be necessary, or at least advisable.
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References
Berridge, J.C. (1982) Unattended optimisation of reversed-phase high-performance liquid chromatographic separations using the modified simplex algorithm. J. Chromatogr.244, 1–14.
Berridge, J.C. (1985) Techniques for the Automated Optimizations of HPLC Separations. Wiley, Chichester, 125–151.
Hermansson, J. (1984) Liquid chromatographic resolution of racemic drugs using a chiral α1 acid glycoprotein column. J. Chromatogr.298, 67–78.
Noctor, T.A.G., B.J. Clarke, and A.F. Fell (1986) Chiral separations of drug enantiomers by HPLC. Anal. Procs.23, 441–443.
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© 1989 Chapman & Hall
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Noctor, T.A.G., Fell, A.F., Kaye, B. (1989). Optimization. In: Lough, W.J. (eds) Chiral Liquid Chromatography. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0861-1_15
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DOI: https://doi.org/10.1007/978-94-009-0861-1_15
Publisher Name: Springer, Dordrecht
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