Abstract
In 1914 Ramon y Cajal [1] stated that “… in the adult central nervous system (CNS) the nervous pathways are something fixed, finished and immutable. All may die, nothing may be reborn”. This concept aside, Cajal however pointed out that mature central fibres fail to regrow because of the absence of some “auxliary factors” or “catalytic substances”, which are present during ontogenic development, but may be missing in the adult stage.
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Consolazione, A. (1990). Neuronal plasticity in the central nervous system: a pharmacological approach. In: Cazzullo, C.L., Sacchetti, E., Conte, G., Invernizzi, G., Vita, A. (eds) Plasticity and Morphology of the Central Nervous System. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0851-2_18
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DOI: https://doi.org/10.1007/978-94-009-0851-2_18
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