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Biological Monitoring of Lead Exposure in Children: Overview of Selected Biokinetic and Toxicological Issues

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Lead Exposure and Child Development

Summary

The biological monitoring of lead exposure in paediatric and adult human populations has usually involved one of two approaches: (1) measurement of the internal or systemic dose of lead itself in some indicator medium, or (2) quantification of some ‘subcritical’ effect of lead. The extent to which biological monitoring in humans accurately states both exposure risk and relative health risk remains the subject of much research. Of particular interest are (1) the biokinetic characteristics of the common indicators of exposure, (2) the development and use of kinetic models of lead metabolism, and (3) the relative merits of the use of biological effect indicators versus measurement of the toxicant in some medium.

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Authors
  1. P. Mushak
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Editor information

Editors and Affiliations

  1. Department of Child Psychiatry, Institute of Child Health Hospital for Sick Children, Great Ormond Street, London, UK

    M. A. Smith

  2. Environmental Criteria and Assessment Office Office of Health and Environment Assessment US Environmental Protection Agency, Research Triangle Park, 27711, NC, USA

    L. D. Grant (Director) (Director)

  3. Environment Research Programme, Commission of the European Communities, Rue de la Loi 200, B-1049, Brussels, Belgium

    A. I. Sors (Directorate-General for Science, Research and Development) (Directorate-General for Science, Research and Development)

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© 1989 ECSC-EEC-EAEC, Brussels — Luxembourg; EPA, USA

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Mushak, P. (1989). Biological Monitoring of Lead Exposure in Children: Overview of Selected Biokinetic and Toxicological Issues. In: Smith, M.A., Grant, L.D., Sors, A.I. (eds) Lead Exposure and Child Development. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0847-5_4

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  • DOI: https://doi.org/10.1007/978-94-009-0847-5_4

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6868-0

  • Online ISBN: 978-94-009-0847-5

  • eBook Packages: Springer Book Archive

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