Abstract
Septic arthritis is a medical emergency requiring early diagnosis and effective antimicrobial treatment. Though the great majority of cases have a satisfactory outcome, one of the most striking features is the rapid destruction of cartilage and bone tissue that can occur, frequently leading to permanent joint damage.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Powanda, M. C., Oppenheim, J. J., Kluger, M. J. and Dinarello, C. A. (eds.) (1988). Monokines and Other Non-Lymphocytic Cytokines, Vol. 8 (New York: Alan R. Liss, Inc.)
Bock, J. and Marsh, J. (eds.) (1987). Tumour Necrosis Factor and Related Cytotoxins, Ciba Foundation Symposium (Chichester, UK: J. Wiley)
Gowen, M., Wood, D. D., Ihrie, E. J., McGuire, M. K. B., Graham, R. and Russel, R. G. G. (1983). An interleukin 1-like factor stimulates bone resorption in vitro. Nature (London), 306, 378–380
Bertolini, D. R., Nedwin, G. E., Bringman, T. S., Smith, D. D. and Mundy, G. R. (1986). Stimulation of bone resorption and inhibition of bone formation in vitro by human tumor necrosis factor. Nature (London), 319, 516–518
Saklatvala, J. (1981). Characterization of catabolin, the major product of synovial tissue that induces resorption of cartilage proteoglycan in vitro. Biochem. J., 199, 705–714
Saklatvala, J. (1986). Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature (London), 322, 547–549
Duff, G. W., Dickens, E., Wood, N., Manson, J., Symons, J., Poole, S. and di Giovine, F. S. (1988). Immunoassay, bioassay and in situ hybridization of monokines in human arthritis. In Powanda, M. C., Oppenheim, J. J., Kluger, M. J. and Dinarello, C. A. (eds.) Monokines and Other Non-Lymphocytic Cytokines, pp. 387–392. (New York: Alan R. Liss, Inc.)
Di Giovine, F. S., Nuki, G. and Duff, G. W. (1988). Tumour necrosis factor in synovial exudates. Ann. Rheum. Dis., 47, 768–772
March, C. J., Mosley, B., Larsen, A., Cerretti, D. P., Braedt, G., Price, V., Gillis, S., Henney, C. S., Kronheimm, S. R., Grabstein, K., Conlon, P. J., Hopp, T. P. and Cosman, D. (1985). Cloning, sequencing and expression of two distinct human interleukin 1 complementary cDNAs. Nature (London), 315, 641–647
Clark, D. B., Collins, K. L., Gandy, M. S., Webb, A. C. and Auron, P. E. (1986). Genomic sequence for human prointerleukin 1 beta — possible evolution from a reverse transcribed prointerleukin 1 alpha gene. Nucleic Acids Res., 14, 7897–7914
Furutani, Y., Notake, M., Fukui, T., Ohue, M., Nomura, H., Yamada, M. and Nakamura, S. (1986). Complete nucleotide sequence of the gene for human interleukin 1 alpha. Nucleic Acids Res., 14, 3167–3179
Dower, S. K., Kronheim, S. R., March, C. J., Conlon, P. J., Hopp, T. D., Gillis, S. and Urdal, D. (1985). Detection and characterization of high affinity plasma membrane receptors for human interleukin 1. J. Exp. Med., 162, 501–515
Bird, T. A. and Saklatvala, J. (1986). Identification of a common class of high affinity receptors for both types of porcine interleukin 1 on connective tissue cells. Nature (London), 324, 263–266
Dinarello, C. A. (1986). Interleukin 1: aminoacid sequences, multiple biological activities and comparison with tumor necrosis factor (cachectin). Year Immunol., 2, 68–89
Di Giovine, F. S., Symons, J. A. and Duff, G. W. (1988). Kinetics of cytokine mRNA and protein accumulation in activated monocytes. (In press)
Sims, J. E., March, C. J., Cosman, D., Widmer, M. B., Robson MacDonald, H., McMahan, C. J., Grubin, C. E., Wignall, J. M., Jackson, J. L., Call, S. D., Friend, D., Alpert, A. R., Gillis, S., Urdal, D. L. and Dower, S.K. (1988). cDNA expression and cloning of the IL1 receptor, a member of the immunoglobulin superfamily. Science, 241, 585–589
Saklatvala, J., Sarsfield, S. J. and Townsend, Y. (1985). Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever. J. Exp. Med., 162, 1208–1222
Gowen, M., Wood, D. D., Ihrie, E. J., Meats, J. E. and Russell, R. G. G. (1984). Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro. Biochim. Biophys. Acta., 797, 186–193
Dayer, J. M., Krane, S. M., Russell, R. G. G. and Robinson, D. R. (1976). Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells. Proc. Natl Acad. Sci. USA, 73, 945–951
Pettipher, E. R., Higgs, G. A. and Henderson, B. (1986). Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. Proc. Natl. Acad. Sci. USA, 83, 8749–8753
Dingle, J. T., Page, D. P., King, T. B. and Bard, D. R. (1987). In vivo studies of articular tissue damage mediated by catabolin/interleukin 1. Ann. Rheum. Dis., 46, 527–533
Beutler, B. and Cerami, A. (1986). Cachectin and tumour necrosis factor as two sides of the same biological coin. Nature (London), 320, 584–588
Dayer, J. M., Beutler, B. and Cerami, A. (1985). Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. J. Exp. Med., 162, 2163–2168
Dinarello, C. A. (1987). The biology of interleukin 1 and comparison to tumour necrosis factor. Immunol. Lett., 16, 227–232
Durum, S. K., Schmidt, J. A. and Oppenheim, J. J. (1985). Interleukin 1: an immunological perspective. Annu. Rev. Immunol., 3, 263–287
Kaye, J., Gillis, S., Mizel, S. B., Shevach, E. M., Malek, T. R., Dinarello, C. A., Lachman, L. B. and Janeway, C. A. (1984). Growth of a cloned helper T-cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J. Immunol., 133, 1339–1344
Van Damme, J., DeLey, M., Van Snick, J., Dinarello, C. A. and Billiau, A. (1987). The role of interferon beta and the 26 kD protein (interferon beta 2) as mediators of the antiviral effect of interleukin 1 and tumour necrosis factor. J. Immunol., 139, 1867–1872
Atkins, E. (1960). The pathogenesis of fever. Physiol. Rev., 40, 580–646
Eastgate, J. A., Symons, J. A., Wood, N. C., Grinlinton, F. M., di Giovine, F. S. and Duff, G. W. (1988). Correlation of plasma interleukin 1 levels with disease activity in rheumatoid arthritis. Lancet, 2, 706–709
Di Giovine, F. S., Meager, A., Leung, H. and Duff, G. W. (1988). Immunoreactive tumour necrosis factor alpha and biological inhibitor(s) in synovial fluids from rheumatic patients. Int. J. Immunopathol. Pharmacol., 1, 17–26
Symons, J. A., Wood, N. C., Di Giovine, F. S. and Duff, G. W. (1988). Soluble IL-2 receptor in rheumatoid arthritis: correlation with disease activity, IL-1, and IL-2 inhibition. J. Immunol., 141, 2612–2618
Manson, J. C., Symons, J. A., di Giovine, F. S., Poole, S. and Duff, G. W. (1988). Autoregulation of interleukin 1 production. Eur. J. Immunol. (In press)
Wood, N. C., Symons, J. A. and Duff, G. W. (1988). Serum interleukin-2-receptor in rheumatoid arthritis: a prognostic indicator of disease activity? J. Autoimmun., 1, 353–361
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Kluwer Academic Publishers
About this chapter
Cite this chapter
Di Giovine, F.S., Symons, J.A., Duff, G.W. (1989). Interleukin 1 and Tumour Necrosis Factor in the Pathogenesis of Septic Arthritis. In: Calabro, J.J., Dick, W.C. (eds) Infections and Arthritis. New Clinical Applications Rheumatology , vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0845-1_8
Download citation
DOI: https://doi.org/10.1007/978-94-009-0845-1_8
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6867-3
Online ISBN: 978-94-009-0845-1
eBook Packages: Springer Book Archive