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Viral Infections and Chronic Arthritis

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Infections and Arthritis

Part of the book series: New Clinical Applications ((NCRH,volume 2))

Abstract

The cause of a variety of chronic diseases, including arthritis, has been attributed to infection almost since the discovery of bacteria. Epidemiological, genetic, laboratory and experimental observations suggest that chronic arthritis may be a sequela of infection. With the failure to identify bacteria from within joints in rheumatoid arthritis, and with the development of techniques to detect viruses, there has been recent emphasis on seeking a virus as the cause of the characteristic persistent immune response that is seen in the synovium. It was first clearly documented1 that a virus can be associated with arthritis during an epidemic of rubella at the end of World War I. Viruses can also cause chronic inflammatory disease2,3, can evade detection and new human viruses are now often being identified4.

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Woolf, A.D. (1989). Viral Infections and Chronic Arthritis. In: Calabro, J.J., Dick, W.C. (eds) Infections and Arthritis. New Clinical Applications Rheumatology , vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0845-1_3

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