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Influence of Buserelin on Testicular Tissue After Long-Term Treatment for Precocious Puberty and Prostatic Cancer

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GnRH Analogues in Cancer and Human Reproduction

Abstract

GnRH analogs have been successfully used in the treatment of precocious puberty and prostatic carcinoma and may have potential as male contraceptive drugs. Following high doses, desensitization of the pituitary results, and testosterone levels drop to the levels found in castrated males. The purpose of this study was to examine effects of long-term, high dose, GnRH analog (buserelin) upon the human testis.

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References

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Author information

Authors and Affiliations

  1. Children’s Hospital Basle, Römergasse 8, CH-4005, Basle, Switzerland

    F. Hadziselimovic

Authors
  1. F. Hadziselimovic
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Editor information

Editors and Affiliations

  1. Syntex Research, Institute of Biological Science, Palo Alto, CA, 94304, USA

    B. H. Vickery

  2. Institute of Endocrinology, Sheba Medical Center and Bar Ilan University, Remat Gan, 52621, Israel

    B. Lunenfeld

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© 1990 Kluwer Academic Publishers

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Hadziselimovic, F. (1990). Influence of Buserelin on Testicular Tissue After Long-Term Treatment for Precocious Puberty and Prostatic Cancer. In: Vickery, B.H., Lunenfeld, B. (eds) GnRH Analogues in Cancer and Human Reproduction. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0725-6_11

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  • DOI: https://doi.org/10.1007/978-94-009-0725-6_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6811-6

  • Online ISBN: 978-94-009-0725-6

  • eBook Packages: Springer Book Archive

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