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Testicular Changes in Patients with Buserelin for Precocious Puberty

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GnRH Analogues in Cancer and Human Reproduction

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Abstract

The identification and purification of the GnRH molecule has led to the availability of several long-acting GnRH analogues, whose in vitro and in vivo effect on the pituitary is to suppress gonadotrophin release when given repeatedly over a period of time. Hence these compounds have assumed a useful role in the treatment of centrally mediated precocious puberty.

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References

  1. Boepple, PA, Mansfield, MJ, Wierman, ME, Rudlin, CR, Bode, HH, Crigler, JF Jr., Crawford, JD and Crowley, WF Jr. (1986). Use of a potent, long acting agonist of gonadotrophin-releasing hormone in the treatment of precocious puberty. Endocr Rev, 7, 24

    Article  PubMed  CAS  Google Scholar 

  2. Pescovitz, OH, Comite, F, Hench, K, Barnes, K, McNemar, A, Foster, C, Kenigsberg, D, Loriaux, L and Cutler GB Jr (1986). The NIH experience with precocious puberty: Diagnostic subgroups and response to short-term luteinizing hormone releasing hormone analogue therapy. J Ped, 108, 47

    Article  CAS  Google Scholar 

  3. Weinbauer, GF, Respondek, M, Themann, H, and Nieschlag, E (1187). Reversibility of long-term effects of GnRH agonist administration on testicular histology and sperm production in the nonhuman primate. J Androl, 8, 138

    Google Scholar 

  4. Mann, DR, Smith, MM, Gould, KG and Collins, DC (1985). Effect of a gonadotrophin-releasing hormone agonist on luteinizing hormone and testosterone secretion and testicular histology in male rhesus monkeys. Fertil Steril, 43, 115

    PubMed  CAS  Google Scholar 

  5. Barham, SS and Berlin, JD (1974). Fine structure and cytochemistry of testicular cells in men treated with testosterone propionate. Cell Tiss Res, 148, 159

    Article  CAS  Google Scholar 

  6. Rajfer, J, Swerdloff, R and Heber, DM (1984). Testicular histology following chronic gonadotropin-releasing hormone agonist treatment. Fertil Steril, 42, 765

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Departments of Pediatrics and Pathology, University of British Columbia, BC’s Children’s Hospital, Vancouver, BC, Canada, V6H 3V4

    W. J. Tze, B. Gilks, H. Kitson, R. M. Couch, G. P. Taylor & P. Merat

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  1. W. J. Tze
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  2. B. Gilks
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  3. H. Kitson
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  4. R. M. Couch
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  5. G. P. Taylor
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  6. P. Merat
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Editor information

Editors and Affiliations

  1. Syntex Research, Institute of Biological Science, Palo Alto, CA, 94304, USA

    B. H. Vickery

  2. Institute of Endocrinology, Sheba Medical Center and Bar Ilan University, Remat Gan, 52621, Israel

    B. Lunenfeld

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© 1990 Kluwer Academic Publishers

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Tze, W.J., Gilks, B., Kitson, H., Couch, R.M., Taylor, G.P., Merat, P. (1990). Testicular Changes in Patients with Buserelin for Precocious Puberty. In: Vickery, B.H., Lunenfeld, B. (eds) GnRH Analogues in Cancer and Human Reproduction. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0725-6_10

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  • DOI: https://doi.org/10.1007/978-94-009-0725-6_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6811-6

  • Online ISBN: 978-94-009-0725-6

  • eBook Packages: Springer Book Archive

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