Abstract
Coronary angiography is the current ‘gold standard’ in the evaluation of the severity of coronary disease; the parameter usually adopted is the percent diameter of the visualized stenosis. The limitation of this approach is that it does not take into consideration other geometric features of the stenosis (such as the length and absolute value of the area of the lumen vessel at the point of the stenosis). In any case even an objective measurement of each of these parameters would not make it possible to predict the actual reduction in perfusion.
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References
Gould KL, Lipscomb K, Hamilton GW (1974) Physiologic basis for assessing critical coronary stenosis. Am J Cardiol 33: 87–94.
Hodgson JM, LeGrand V, Bates ER, Mancini J, Aueron M, O’Neill WW, Simon SB, Beau- man GJ, LeFree MT, Vogel RA (1985) Validation in dogs of a rapid digital angiographic technique to measure relative coronay blood flow during routine cardiac catheterization. Am J Cardiol 55: 188–193.
Nissen SE, Elion JL, Booth DC, Evans J, DeMaria AN (1986) Value and limitations of computer analysis of digital subtraction angiography in the assessment of coronary flow reserve. Circulation 73: 562–571.
Nishimura R, Togers PJ, Holmes DR, Gehring DG, Bove AA (1987) Assessment of myocardial perfusion by videodensitometry in the canine model. J Am Coll Cardiol 9: 891–897.
Marcus M, Wright C, Doty D, Eastham C, Laughlin D, Krumm P, Fastenow C, Brody M (1981) Measurements of coronary velocity and reactive hyperemia in the coronary circulation of humans. Circ Res 49: 877–891.
Wilson RF, Laughlin DE, Ackell PH, Chillian WM, Holida MD, Hartley CJ, Armstrong ML, Marcus ML, White CW (1985) Transluminal subselective measurement of coronary artery blood flow velocity and vasodilatory reserve in man. Circulation 72: 82.
Beyar R, Sideman S (1987) Time-dependent coronary blood flow distribution in left ventricular wall. Am J Physiol 252: H417–H433.
Marcus ML (1983) Transmural distribution of myocardial perfusion, in: The Coronary Circulation in Health and Disease. New York: Mc Graw Hill Book Company.
Bergmann SR, Fox KAA, Geltman EM, Sobel BE (1985) Positron emission tomography of the heart. Prog Cardiovasc Dis 28: 165.
Cerqueira MD, Harp GD, Ritchie JL (1987) Evaluation of myocardial perfusion and function by single photon emission computed tomography. Seminars in Nuclear Medicine 17: 200–213.
Gould KL, Goldstein RA, Mullani NA, Kirkeeide RL, Wong WH, Tewson TJ, Berridge MS, Bolomey LA, Hartz RK, Smalling WR, Fuentes F, Nishikawa A (1986) Non-invasive assessment of coronary stenoses by myocardial perfusion imaging during pharmacologic coronary vasodilation. VIII. Clinical feasibility of positron cardiac imaging without a cyclo- ton using generator-produced rubidium-82. J Am Coll Cardiol 7: 775–789.
Armstrong WF, Mueller TM, Kinney EL, Thickner EG, Dillon JC, Feigenbaum H (1982) Assessment of myocardial perfusion abnormalities with contrast enhanced two-dimensional echocardiography. Circulation 66: 166–173.
Tei C, Sakamaki T, Shah PM, Meerbaum S, Shimoura K, Kondo S, Corday E (1983) Myo-cardial contrast echocardiography: Reproducible technique of myocardial opacification for identifying regional perfusion deficits. Circulation 67: 585–592.
Kemper AJ, O’Boyle JE, Sharma S, Cohen CA, Kloner RA, Khuri SF, Parisi AF (1983) Hydrogen peroxide contrast-enhanced two-dimensional echocardiography: Real-time in vivo delineation of regional myocardial perfusion. Circulation 68: 603–611.
Maurer G, Ong K, Haendchen R, Torres M, Tei C, Wood F, Meerbaum S, Shah P, Corday E (1984) Myocardial contrast two-dimensional echocardiography: Comparison of contrast disappearance rate in normal and underperfused myocardium. Circulation 69: 418–429.
Tei C, Kondo S, Meerbaum S, Ong K, Maurer G, Wood F, Sakamaki T, Shimoura K, Corday E, Shah PM (1984) Correlation of myocardial echo contrast disappearance rate (‘washout’) and severity of experimental stenosis. J Am Coll Cardiol 3: 39–46.
Ten Cate FJ, Drury K, Meerbaum S, Noorsdy J, Feinstein S, Shah PM, Corday E (1984) Myocardial contrast two-dimensional echocardiography: Experimental examination at different coronary flow levels. J Am Coll Cardiol 3: 1219–1226.
Kondo S, Tei C, Meerbaum S, Corday E, Shah PM (1984) Hyperemic response of intra- coronary contrast agents during two-dimensional echographic delineation of regional myocardium. J Am Coll Cardiol A: 149–156.
Zotz RJ, Carls R, Erbel R, Clas W, Brenneke R, Meyer J (1986) A new method to quantify myocardial perfusion deficits in patients. Circulation 74 (II): 475.
Monaghan MJ, Quigley PJ, Metcalfe JM, Jevitt DE (1987) Assessment of myocardial perfusion by contrast enhanced digital subtraction echocardiography. J Am Coll Cardiol 9: 112A.
Cheirif J, Zoghbi WA, Zehler A, Winters WL, Bolli R, Lacy JL, Quinones MA (1987) Quantitative assessment of coronary reserve in critical stenosis by sonicated contrast echo-cardiography: Comparison with microspheres and Doppler flow probe. J Am Coll Cardiol 9: 112A.
Zots RJ, Kann B, Brenneke R (1984) Evaluation of PTCA by video-intensitometric analysis of contrast echocardiograms. Circulation 76(IV):505.
Vandenberg BF, Kieso R, Fox-Eastham K, Chilian W, Kerber RE (1988) Demonstration of coronary flow reserve with contrast echocardiography. J Am Coll Cardiol 11: 75A.
Keller MW, Smucker M, Burwell M, Glasheen WP, Watson D, Kaul S (1987) Assessment of coronary blood flow reserve using myocardial contrast echocardiography. Circulation 76 (IV): 505.
Kaul S, Oliner JD, Kelly P, Watson DD (1987) Measurement of regional myocardial blood flow using myocardial contrast echocardiography. J Am Coll Cardiol 9: 2A.
Vandenberg BF, Feinstein SB, Kieso RA, Hunt M, Kerber RE (1988) Myocardial risk area and peak gray level measurement by contrast echocardiography: Effect of microbubble size and concentration, injection rate and coronary vasodilation. Am Heart J 115: 733–739.
Spotnitz WD, Keller MW, Nolan SP, Kaul S (1988) Success of internal mammary bypass grafting can be assessed intraoperatively using myocardial contrast echocardiography. J Am Coll Cardiol 16A.
Vandenberg BF, Kieso R, Fox-Eastham K, Chilian W, Kerber RE (1989) Quantitation of myocardial perfusion by contrast echocardiography: Analysis of contrast gray level appearance variables and intracyclic variability. J Am Coll Cardiol 13: 200–206.
Cheirif J, Zoghbi WA, Bolli R, O’Neill PG, Winters WL, Quinones MA (1988) Contrast echocardiography: assessment of endocardial to epicardial blood flow relation during dypiridamole induced hyperemia in experimental coronary stenosis. J Am Coll Cardiol 11: 75A.
Ten Cate FJ, Cornel JH, Widimsky P, Serruys PW, Vletter WB, Mittertreiner WH (1987) Effect of papaverine administration on myocardial echocontrast distribution. Am Heart J 114: 1248–1249.
Ten Cate FJ, Cornell JH, Serruys PW, Vletter WB, Reiber JC (1987) Quantitative myocardial perfusion imaging using contrast two-dimensional echocardiography. J Am Coll Cardiol 9: 112A.
Segil LJ, Dicj CD, Feinstein SB, Silverman P, Reese M (1987) Contrast echocardiography - experimental validation of quantitation of regional intramyocardial coronary blood flow. Circulation 76 (IV): 504.
Rovai D, Lombardi M, Ferdeghini EM, Marzilli M, Distante A, Taddei L, Benassi A, DeMaria AN, L’Abbate A (1987) Colorcoded functional imaging of myocardial perfusion by contrast echocardiography. Circulation 76 (IV): 504.
Rovai D, Lombardini M, Ferdeghini EM, Marzilli M, Distante A, Taddei L, Landini L, Benassi A, L’Abbate A (1988) Detection of regional myocardial underperfusion by contrast-echo functional imaging. J Am Coll Cardiol 11: 76 A.
Rovai D, Lombardi M, Nissen SE, Distante A, Marzilli M, DeMaria AN, L’Abbate A (1987) Spatial and temporal heterogeneity of coronary blood flow by myocardial contrast echocardiography. J Am Coll Cardiol 9: 112A.
Rovai D, Nissen SE, Elion J, Smith M, L’Abbate A, Kwan OL, DeMaria AN (1987) Contrast echo washout curves from the left ventricle: Application of basic principles of indicator-dilution theory and calculation of ejection fraction. J Am Coll Cardiol 10: 125–134.
Powsner SM, Feinstein SB (1987) Quantitative radiofrequency analysis of sonicated echo- contrast agents, in: Roelandt J (ed), Digital Techniques in Echocardiography, pp 13–27. Dordrecht: Martinus Nijhoff Publishers.
Zwehl W, Areda J, Schwartz G, Feinstein S, Ong K, Meerbaum S (1984) Physical factors influencing quantitation of two-dimensional contrast echo amplitudes. J Am Coll Cardiol 4: 157–164.
Reisner SA, Shapiro JR, Amico AF, Meitzer RS (1989) Reproducibility of washout curves derived from myocardial contrast echo. J Am Coll Cardiol 13: 115 A.
Cheirif J, Zoghbi WA, Raizner AE, Minor ST, Winters WL, Klein MS, DeBauche TL, Lewis JM, Roberts R, Quinones MA (1988) Assessment of myocardial perfusion in humans by contrast echocardiography. I. Evaluation of regional coronary reserve by peak contrast intensity. J Am Coll Cardiol 11: 735–743.
Keller MW, Glasheen W, Smucker ML, Burwell LR, Watson DD, Kaul S (1988) Myocardial contrast echocardiography in humans. II. Assessment of coronary blood flow reserve. J Am Coll Cardiol 12: 925–934.
Cheirif J, Zoghbi WA, Bolli R, O’Neill P, Hoyt BD, Quinones MA (1989) Assessment of regional myocardial perfusion by contrast echocardiography. II. Detection of changes in transmural and subendocardial perfusion during dypiridamole-induced hyperemia in a model of critical coronary stenosis. J Am Coll Cardiol 14: 1555–1565.
Reisner SA, Shapiro JR, Amico AF, Meitzer RS (1989) Myocardial contrast echo washout curves: The influence of ischemia and hyperemia. J Am Coll Cardiol 13: 115 A.
Keller MW, Glasheen W, Teja K, Gear A, Kaul S (1988) Myocardial contrast echocardiography without significant hemodynamic effects or reactive hyperemia: A major advantage in the imaging of regional myocardial perfusion. J Am Coll Cardiol 12: 1039–1047.
Reisner SA, Ong SL, Lichtenberg GS, Amico AF, Shapiro JR, Allen MN, Meitzer RS (1989) Myocardial perfusion imaging by contrast echocardiography with use of intracoronary sonicated albumin in humans. J Am Coll Cardiol 14: 660–665.
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Amico, A.F., Iliceto, S., Sublimi Saponetti, L., Memmola, C., Rizzon, P. (1991). Myocardial contrast echocardiography for the evaluation of coronary flow reserve. In: Iliceto, S., Rizzon, P., Roelandt, J.R.T.C. (eds) Ultrasound in Coronary Artery Disease. Developments in Cardiovascular Medicine, vol 113. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0611-2_31
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DOI: https://doi.org/10.1007/978-94-009-0611-2_31
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6762-1
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