Abstract
Upper gastrointestinal (UGI) bleeding is a common and often serious medical and surgical problem (1, 2). Fortunately, most patients hospitalized for UGI bleeding have spontaneous hemostasis and do not rebleed or require urgent surgery. In spite of improvements in endoscopic diagnosis, and medical-surgical care, the mortality rate has not changed in the last 30 years and remains at 8–10% (1–3). Nevertheless, clinical prognostic factors have been identified such as old age, concomitant medical-surgical illness, shock, multiple transfusions of blood, varices, malignancy, active bleeding at endoscopy and rebleeding in the hospital (1–4). Also, for peptic ulcers that have bled, endoscopic major (active bleeding or non-bleeding visible vessel) and minor stigmata of recent hemorrhage (flat red or black spot, grey slough, oozing from granulation tissue and non-bleeding clots) have been identified and used in some studies to randomize patients admitted for UGI hemorrhage (5–9). In controlled clinical trials, the control groups with minor stigmata have had very low rates of rebleeding such as 15–22% for non-bleeding adherent clots and 5–7% for non-bleeding spots (5–9). No improvement in outcomes of such low risk patients has been documented when they are treated by endoscopic argon or YAG laser in controlled randomized trials (5–10). On the other hand, several different controlled studies either with argon laser (7), YAG laser (8, 9, 11), monopolar electrocoagulation (12), or bipolar electrocoagulation (BICAP — 13) have reported significant reductions in rates of continued bleeding-rebleeding or emergency surgery for patients with major stigmata such as active arterial bleeding (7, 8, 11), bleeding from under an adherent clot (9), or a non- bleeding visible vessel (7, 8).
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References
Silverstein FE, Gilbert DA, Tedesco FJ et al. The national ASGE survey on upper gastrointestinal bleeding. Gastrointest Endoscopy 1981; 27: 73 – 102.
Avery Jones F. Haematemesis and melaena with special reference to causation and the factors influencing mortality from bleeding peptic ulcer. Gastroenterology 1956; 30: 166 – 90.
Schiller KRF, Truelove SC, Gwyn Williams D. Haematemesis and melena with special reference to factors influencing the outcome. Br Med J 1970; 2: 7 – 14.
Allen R, Dykes P. A study of the factors influencing mortality rates from gastrointestinal haemorrhage. Quart J Med 1976; 45: 533 – 50.
Storey DW, Bown SG, Swain CP et al. Endoscopic prediction of recurrent bleeding in peptic ulcers. N Engl J Med 1976; 45: 533 – 50.
Vallon AG, cotton PB, Laurence BH et al. Randomized trial of endoscopic argon laser photocoagulation in bleeding peptic ulcers. Gut 1981; 22: 228 – 33.
Swain CP, Bown SG, Storey DW et al. Controlled trial of argon laser photocoagulation in bleeding peptic ulcers. Lancet 1981;ii:1313–16.
Swain CP, Kirkhain JS, Salmon PR et al. Controlled trial of Nd-YAG laser photocoagulation in bleeding peptic ulcers. Lancet 1986;i:1113–7.
Rutgeerts P, Vantrappen G, Broeckaert L et al. Controlled trial of YAG laser treatment of upper digestive hemorrhage. Gastroenterology 1982; 83: 410 – 16.
Krejs GJ, Little KH, Westergaard et al. Laser photocoagulation for treatment of acute peptic ulcer bleeding. A randomized controlled clinical trial. N Engl J Med 1987; 316: 1618 – 1622.
McLeod I A, Mills PR, MacKenzie JF et al. Neodymium yttrium aluminum garnet laser photocoagulation for major haemorrhage from peptic ulcers and single vessels: a single blind controlled study. Br Med J 1983; 286: 345 – 48.
Papp J. Electrocoagulation: Endoscopic control of gastrointestinal hemorrhage. In: Ed J Papp; Boca Raton, Florida: CRC Press. 1983; 31 – 42.
Laine L. Multipolar electrocoagulation in the treatment of active upper gastrointestinal tract hemorrhage: A prospective controlled trial. N Engl J Med 1987; 316: 1613 – 17.
Johnston JH, Jensen DM, Mautner W, Elashoff J. Argon laser treatment of bleeding canine gastric ulcers: Limitations and guidelines for endoscopic use. Gastroenterology 1980; 80: 708 – 16.
Brunetaud JM, Jensen DM. Current status of argon laser hemostasis of bleeding ulcers. Endoscopy 1986;18:Suppl 2:40–45.
Jensen DM. Economic and health aspects of peptic ulcer disease and H2-receptor antagonists. Amer J Med 1986; 81 (Supp 4B), 42 – 48.
Jensen DM, Silpa M, Reedy T et al. Controlled trial of sclerotherapy for bleeding esophageal varices in alcoholic cirrhosis. (Abstract) Gastroenterology 1986;90:Part 2: 1476.
Jensen D, Bown S. Gastrointestinal angiomata: diagnosis and treatment with laser therapy and other endoscopic modalities. In: Fleischer D, Jensen D, Bright-Asare P, Eds. Therapeutic Laser Endoscopy in Gastrointestinal Disease. Boston: Martinus Nijhoff, 1983: 151 – 60.
Johnston JH, Jensen DM, Mautner W. Comparison of laser photocoagulation and electrocoagulation in endoscopic treatment of bleeding canine gastric ulcers. Gastroenterology 1982; 82: 904 – 10.
Jensen DM. Endoscopic control of gastrointestinal bleeding. In: Development in Digestive Diseases. Lea and Febiger Publishers. 1–27, 1980.
Brunetaud JM et al. Photocoagulation laser des hemorragies digestives graves du tractus digestif superieur. Acta Gastro-ent Belg 1982; 45: 47 – 54.
Swain CP, Storey DW, Bown SG et al. The nature of the bleeding vessel in recurrently bleeding gastric ulcers. Gastroenterology 1986; 90: 595 – 608.
Johnston JH. The sentinel clot and invisible vessel: Pathologic anatomy of bleeding peptic ulcer. Gastrointest Endosc 1984; 30: 313 – 14.
Kovacs TOK, Jensen DM. Endoscopic control of gastroduodenal hemorrhage. In: Annual REview of Medicine. Creger WP. Ed. 1987;38:267–77.
Jensen DM, Machicado GA, Silpa M et al. BICAP vs. heater probe for hemostasis of severe ulcer bleeding (Abstract). Gastrointest Endosc 1986; 32: 143.
Johnston JH, Jensen DM, Auth D. Experimental comparison of endoscopic neodymium- yttrium-aluminum-garnet laser, electrosurgery and heater probe for coagulation of canine gut arteries: Importance of compression and avoidance of erosion. Gastroenterology 1987; 92: 1101 – 8
Asaki S, Nishimura T, Satoh A et al. Endoscopic control of gastrointestinal hemorrhage by local injection of absolute alcohol: a clinical study. Tohoku J Exp Med 1983; 141: 373 – 83.
Wordehoff D, Gros H, Stenzel M. Injection of non-variceal bleeding lesions of the gastrointestinal tract. Endoscopy 1985; 17: 129 – 32.
Soehendra N, Grimm H, Stenzel M. Injection of non-variceal bleeding lesions of the gastrointestinal tract. Endoscopy 1985; 17: 129 – 32.
Chung SCS, Leung JWC, Steele RJC et al. Epinephrine injection for actively bleeding ulcers: A randomized controlled study (Abstract). Gastrointestinal Endosc 1987;33,No2:146.
Escourrou J, Frexinos J, Bommelaer G et al. Prospective randomized study of YAG laser photocoagulation in gastrointestinal bleeding. Proceedings of Laser Tokyo 1981. Ed K Atsumi and N Nimsakul 1981; 5 – 30.
Ihre T, Johansson C, Seligson V et al. Endoscopic YAG laser treatment in massive upper gastrointestinal bleeding. Report of a controlled randomized study. Scand J Gastroenterol 1981; 16: 633 – 40.
Jensen DM. Lasers in the GI cancer war and on other fronts. Gastroenterology 1984; 87: 974 – 76.
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Jensen, D.M., Machicado, G.A. (1990). Argon Laser for Severe Ulcer Hemorrhage: Health and Economic Considerations. In: Jensen, D.M., Brunetaud, JM. (eds) Medical Laser Endoscopy. Developments in Gastroenterology, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0507-8_10
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DOI: https://doi.org/10.1007/978-94-009-0507-8_10
Publisher Name: Springer, Dordrecht
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