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5-Hydroxytryptamine and related drugs and autonomic ganglia

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Cardiovascular Pharmacology of 5-Hydroxytryptamine

Abstract

A cardiovascular response to 5-HT will be evoked if, amongst other actions, the amine increases impulse traffic in sympathetic neurones causing vasoconstriction or in autonomic neurones which alter cardiac output. In addition, cardiovascular responses will be modified if 5-HT modulates the output of transmitter at the neuroeffector junction. Cardiovascular actions may also result from 5-HT affecting the afferent limb of reflex pathways.

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Authors
  1. D. I. Wallis
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  2. P. Elliott
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Erasmus University, Rotterdam, The Netherlands

    P. R. Saxena

  2. Department of Physiology, University of Wales, College of Cardiff, Cardiff, UK

    D. I. Wallis

  3. Department of Pharmacology, Duphar B.V, Weesp, The Netherlands

    W. Wouters  & P. Bevan  & 

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Wallis, D.I., Elliott, P. (1990). 5-Hydroxytryptamine and related drugs and autonomic ganglia. In: Saxena, P.R., Wallis, D.I., Wouters, W., Bevan, P. (eds) Cardiovascular Pharmacology of 5-Hydroxytryptamine. Developments in CardioCardiovascular Pharmacology of 5-Hydroxytryptamine, vol 106. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0479-8_14

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  • DOI: https://doi.org/10.1007/978-94-009-0479-8_14

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6701-0

  • Online ISBN: 978-94-009-0479-8

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