Abstract
Patients suffering from hypertrophic scarring secondary to extensive burns have to expect modifications in their social and working life, together with lengthy physiotherapeutic and surgical procedures, in a background of uncertainty as regards the long-term evolution of the scars and the quality of the final result. It is thus important to study the little known aetiopathogenic factors involved, in order to propose new therapeutic approaches in burn scars.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Bibliography
Castagnoli, C, Peruccio, D., Stella, M., Magliacani, M., Mazzola, G., Amoroso, A. and Richiardi, P. (1990). The HLA-DR beta 16 allogenotype constitutes a risk factor for hypertrophic scarring. Hum. Immunol., 29, 229–232.
Castagnoli, C, Stella, M., Peruccio, D., Richiardi, P. and Magliacani, G. (1990). HLA susceptibility factors in hypertrophic scarring. Proceedings of the 8th International Congress on Burn Injuries, New Delhi, India.
Cracco, C., Stella, M., Teich-Alasia, S. and Filogamo, G. (1992). Comparative study of Langerhans cells in normal and pathological human scars. II. Hypertrophic scars. Eur. J. Histochem., 36, 53–65.
Duncan, M. R. and Berman, B. (1989). Differential regulation of collagen, glycosaminoglycan, fibronectin, and collagenase activity production in cultured human adult dermal fibroblasts by interleukin 1-alpha and beta and TNF alpha and beta. J. Invest. Dermatol., 92, 699.
Jacob, C. O. and McDevitt, H. O. (1988) TNF alpha in murine autoimmune lupus nephritis. Nature (Lond.), 331, 356.
Jacob, C. O., Fronek, Z., Lewis, G. D., Koo, M., Hansen, J. A. and McDevitt, H. O. (1990). Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc. Natl Acad. Sci. USA, 87, 1233.
Kovacs, E. (1991). Fibrogenic cytokines: the role of immune mediators in the development of scar tissue. Immunol. Today, 12, 17.
Muir, I. F. K. (1990). On the nature of keloids and hypertrophic scars. Br. J. Plast. Surg., 43, 61–69.
Stella, M., Castagnoli, C, Magliacani, G. and Richiardi P. (1989). Fisiopatologia della cicatrice ipertrofica (revisione bibliografica). Riv. Ital. Chir. Plast., 21, 199.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Kluwer Academic Publishers
About this chapter
Cite this chapter
Magliacani, G., Stella, M., Castagnoli, C., Richiardi, P. (1995). The Expression of HLA-DR, IL-2R, ICAM-1 and TNF Alpha Molecules as Possible Prognostic Elements of Hypertrophic Scarring in Burns. In: Masellis, M., Gunn, S.W.A. (eds) The Management of Burns and Fire Disasters: Perspectives 2000. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0361-6_41
Download citation
DOI: https://doi.org/10.1007/978-94-009-0361-6_41
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6647-1
Online ISBN: 978-94-009-0361-6
eBook Packages: Springer Book Archive