Skip to main content

Nonporous Silica Microspheres in the Micron and Submicron Size Range

Manufacture, characterization and application

  • Chapter
Fine Particles Science and Technology

Part of the book series: NATO ASI Series ((ASHT,volume 12))

Abstract

Uniform nonporous silica microspheres in the micrometer and submicrometer size range are formed by a process which involves reacting alkoxysilanes with water in a short chain alcohol using dissolved ammonia as a morphological catalyst.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. G. Kolbe, Dissertation (1956) Jena, Germany

    Google Scholar 

  2. W. Stöber, A. Fink and E. Bohn, (1968), Controlled Growth of Monodisperse Silica Spheres in the Micron Range, J. Colloid Interface Sci., 26, 62

    Article  Google Scholar 

  3. C. Kaiser, Diploma thesis, 1993, Mainz, Germany

    Google Scholar 

  4. H. Reichert, Diploma thesis, 1986, Universität Mainz, Germany

    Google Scholar 

  5. A.K. Van Helden, J.W. Jansen and A. Vrij, (1980) Preparation and Characterization of Spherical Monodisperse Silica Dispersions in Nonaqueous Solvents, 81, 354

    Google Scholar 

  6. T. Matsoukas and E. Gulari, (1988), Dynamics of Growth of Silica Particles from Ammonia-Catalyzed Hydrolysis of Tetra-ethyl-orthosilicateJ. Colloid Interface Sei., 124, 252

    Article  CAS  Google Scholar 

  7. A.P. Philips and A. Vrij, (1987), Polydispersity probed by Light Scattering of Secondary particles in controlled growth experiments of Silica Spheres J. Chem. Phys., 87, 5634

    Article  Google Scholar 

  8. A. van Blaaderen, J. van Geest and A. Vrij, (1992), Monodisperse Colloidal Silica Spheres from Tetraalkoxysilanes: Particle Formation and Growth Mechanism, J. Colloid Interface Sci. 154, 481

    Article  Google Scholar 

  9. H. Giesche, Dissertation, 1987, Mainz, Germany

    Google Scholar 

  10. C.G. Tan, B.D. Bowen., N. Epstein, (1987), Production of monodisperse Silica Spheres: Effect of Temperature, J. Colloid Interface Sci., 118, 290–293

    Article  CAS  Google Scholar 

  11. K.K.Unger and H. Giesche, US patent 4, 775, 520

    Google Scholar 

  12. E. sz. Kovats, L. Jelinek, C. Erbacher, Europian patent EP0.574.642 Al

    Google Scholar 

  13. S. Coenen and C.G. de Kruif, (1988), Synthesis and Growth of Colloidal Silica Particles, J. Colloid Interface Sci., 124, 104–110

    Article  CAS  Google Scholar 

  14. T. J. Barder, P.D. Dubois, US patent 4. 983. 369

    Google Scholar 

  15. A.P. Philipse, (1988), Quantitative aspects of the growth of (charged) silica spheres, Colloid Polym. Sci., 266, 1174

    Article  CAS  Google Scholar 

  16. E. Matijevic, (1981), Monodispersed Metal (Hydrous) Oxide–A Fascinating Field of Colloid Science, Acc, Chem. Res., 14, 22–29

    Article  CAS  Google Scholar 

  17. V. LaMer and R.H. Dinegar, (1950), Theory, Production and Mechanism of Formation of Monodispersed Hydrosols, J. Am. Chem. Soc., 72, 4847–4854

    Article  CAS  Google Scholar 

  18. T. Matsoukas and E. Gulari, (1989) Monomer-Addition Growth with a Slow InitiationStep: A Growth Model for Silica Particles from Alkoxides, J. Colloid Interface Sci., 132, 13–21

    Article  CAS  Google Scholar 

  19. T. Matsoukas and E. Gulari, (1988), Dynamics of Growth of Silica Particles from Ammonia- Catalyzed Hydrolysis of Tetra-ethyl-orthosilicate, J. Colloid Interface Sei., 124, 252–261

    Article  CAS  Google Scholar 

  20. T. Matsoukas and E. Gulari, (1991), Self Sharpening Distributions Revisited–Polydispersity in Growth by Monomer Addition, J. Colloid Interface Sci., 145, 557–562

    Article  CAS  Google Scholar 

  21. G.H. Bogush, C.F. Zukoski IV, (1991), Studies of the kinetics of the precipitation of uniform silica particles through the Hydrolysis and Condensation of silicon alkoxides, J. Colloid Interface Sci., 142, 1–18

    Article  CAS  Google Scholar 

  22. G.H. Bogush, C.F. Zukoski IV, (1991), Uniform Silica Particle Precipitation: An Aggregative Growth Model, J. Colloid Interface Sci., 142, 19

    Article  CAS  Google Scholar 

  23. M. Holik, 2nd NMR Seminar, Prague, 1974

    Google Scholar 

  24. M. Holik and B. Matejková, (1981), Determination of Hydroxyl Groups and Water Content in Silica by Nuclear Magnetic Resonance Spectroscopy, J. Chromatogr., 213, 33–39

    Article  CAS  Google Scholar 

  25. H. Reichert, Diploma thesis 198.., Universität Mainz, Germany

    Google Scholar 

  26. H.G. Barth and R.B. Flippen, Anal. Chem. 67 (1995) 257R

    Article  Google Scholar 

  27. A. van Blaaderen and A.P.M. Kentgens, (1992), Particle morphology and chemical microstructure of colloidal silica spheres made from alkoxysilanes, J. Non-Cryst. Solids 149, 161

    Article  Google Scholar 

  28. K.C. Vrancken, L. De Coster, P. Van Der Voort, P.J. Grobertetc. J. Colloid Interface Sci 170 (1995) 71

    Article  CAS  Google Scholar 

  29. A. van Blaaderen and J. Vrij, (1992), Synthesis and Characterization of Monodisperse Colloidal Organo-silica spheres, J. Colloid Interface Sci. 156 1

    Article  Google Scholar 

  30. J. N. Kinkel, Dissertation, Universität Mainz, 1984, Germany

    Google Scholar 

  31. R.D. Badley, W.T. Ford, F.J. McEnroe and R.A. Assink, Surface Modification of Colloidal Silica, Langmuir 6 (1990) 792

    Article  CAS  Google Scholar 

  32. J.W. de Haan, H.M. Van den Bogart, J.J. Ponjeé and L.J.M. van de Ven, (1986), Characterization of Modified Silica Powders by Fourier Transform Infrared Spectroscopy and Cross Polarization Magic Angle Spinning NMR, J. Colloid Interface Sci. 110 591–600

    Article  Google Scholar 

  33. K.C. Vrancken, L. De Coster, P. Van Der Voort, P.J. Grobertetc. J. Colloid Interface Sci 170 (1995) 71

    Article  CAS  Google Scholar 

  34. C. Apel, R. Jordan, K.K. Unger, HPLC 1995, Insbruck, Austria

    Google Scholar 

  35. J. Edwards, S. Lenon, A.F. Toussaint, B. Vincent, ACS Symp Ser. 240 (1984) 281

    Article  CAS  Google Scholar 

  36. H. Ben Ouda, H. Hommel, A.P. Legrand, H. Balard, E. Papirer, J. Colloid Interface Sci. 122 (1988) 441

    Article  Google Scholar 

  37. K. Bridger, B. Vincent, Eur. Polym. J. 16 (1980) 1017

    Article  Google Scholar 

  38. E. Schomaker, A.-J. Zwarteveen, G. Challa, M. Capka, Polym. Commun. 29 (1988) 158

    CAS  Google Scholar 

  39. G. Schomburg, LC-GC, 6 (1988) 37

    Google Scholar 

  40. M. Hanson, K.K. Unger and G. Schomburg, J. Chromatogr. 517 (1990) 269

    Article  CAS  Google Scholar 

  41. U. Bien-Vogelsang, A. Deege, H. Figge, J. Köhler, G. Schomburg, Chromatographia 19 (1984) 170

    Article  CAS  Google Scholar 

  42. H. Figge, A.Deege, J. Köhler, G. Schomburg, J. Chromatogr. 351 (1986) 393

    Article  CAS  Google Scholar 

  43. K.K. Unger, J.N. Kinkel, B.Anspach and H.Giesche, Evaluation of Advanced Silica Packings for the Separation of Biopolymers by High Performance Liquid Chromatography, I. Design and Properties of Parent Silicas, J. Chrom., 296 (1984) 3–14

    Article  CAS  Google Scholar 

  44. K.K. Unger, G.Jilge, J.N. Kinkel and M.T.W. Hearn, (1986), Evaluation of Advanced Silica Packings for the Separation of Biopolymers by High-Performance Liquid Chromatography H. Performance of Non-Porous Monodisperse 1.5 μm Silica Beads in the Separation of Proteins by Reversd-Phase Gradient Elution High Performance Liquid Chromatography, J. Chromatogr., 359, 61–72

    Article  CAS  Google Scholar 

  45. R. Janzen, K.K. Unger, H. Giesche, J.N. Kinkel and M.T.W Heam, (1987), Evaluation of Advanced Silica Packings for the Separation of Biopolymers by High-Performance Liquid Chromatography V. Performance of Non-Porous Monodisperse 1.5 μm Bonded Silicas in the Separation of Proteins by Hydrophobic-Interaction Chromatography, J. Chromatogr., 397, 91–97

    Article  CAS  Google Scholar 

  46. G. Jilge, K.K. Unger, U.Esser, H.-J. Schäfer, G. Rathgeber and W. Müller, (1989) Design, Chromatographic Performance and Apllication of Non-Porous Silica Based Anion Exchangers, J. Chromatogr., 476, 135–145

    Article  Google Scholar 

  47. H. Giesche, K.K. Unger, U. Esser, B. Fray, U. Trudinger and J.N. Kinkel, (1989) Packing Technology, Column Bed Structure and Chromatographic Performance of 1–2 µm Non-Porous Silicas in High Performance Liquid Chromatography, J. Chromatogr., 465, 39–57

    Article  CAS  Google Scholar 

  48. H. Giesche, Dissertation, 1989, Mainz, Germany

    Google Scholar 

  49. H. Giesche and K.K. Unger (1989) in H. Hauser and G.L. Messing (editors): Ceramic Powder Processing Science, 2nd Int. Conference, Berchtesgaden, Germany 1988, Deutsche Keramische Gesellschaft, Köln

    Google Scholar 

  50. H. Giesche, K.K. Unger and U. Esser, (1989), Hysteresis in Nitrogen Sorption and Mercury Porosimetry on Mesoporous Model Adsorbents Made of Aggregated Monodisperse Silica Spheres, 37, 93–113

    Google Scholar 

  51. A.I. Liapis, B. Anspach, M.E. Findley, J. Davies, M.T.W. Hearn and K.K. Unger, (1989) Biospecitic Adsorption of Lysozyme onto Monoclonal Antibody Ligand Immobilized on Non-Porous Particles, Biotechnology and Bioengineering, 34, 467–477

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Kluwer Academic Publishers

About this chapter

Cite this chapter

Kaiser, C., Hanson, M., Giesche, H., Kinkel, J., Unger, K.K. (1996). Nonporous Silica Microspheres in the Micron and Submicron Size Range. In: Pelizzetti, E. (eds) Fine Particles Science and Technology. NATO ASI Series, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0259-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-0259-6_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-7923-4047-8

  • Online ISBN: 978-94-009-0259-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics