Abstract
This report provides a short introduction *) into the general topic of the two lectures given, followed by copies of the complete set of slides shown in these lectures (Lecture 1, Figs. 1–43; Lecture 2, Figs. 44–78), whereby each slide figure is complemented by a short commentary.
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Eschenmoser, A. (1991) Warum Pentose- und nicht Hexose-Nucleinsäuren?, Nachr. Chem. Tech. Lab. 39, 795–806.
Eschenmoser, A. and Dobler, M. (1992) Why Pentose and Not Hexose Nucleic Acids? Part I. Introduction to the Problem, Conformational Analysis of Oligonucleotide Single Strands Containing 2’,3’-Dideoxyglucopyranosyl Building Blocks (‘Homo-DNA’), and Reflections on the Conformation of A- and B-DNA,Helv. Chim. Acta 75, 218–259.
Müller, D., Pitsch, S., Kittaka, A., Wagner, E., Wintner, C.E., and Eschenmoser, A. (1990) Chemie von α-Aminonitrilen. Aldomerisierung von Glykolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die Reaktionshauptprodukte, Helv. Chim. Acta 73, 1410–1468.
Böhringer, M., Roth, H.- J., Hunziker, J., Göbel, M., Krishnan, R., Giger, A., Schweizer, B., Schreiber, J., Leumann, C, and Eschenmoser, A.(1992) Why Pentose and Not Hexose Nucleic Acids? Part II. Preparation of Oligonucleotides Containing 2‘,3’-Dideoxy-β-D-glucopyranosyl Building Blocks, Helv. Chim. Acta 75, 1416–1477.
Hunziker, J., Roth, H.- J., Böhringer, M., Giger, A., Diederichsen, U., Göbel, M., Krishnan, R., Jaun, B., Leumann, C, and Eschenmoser, A. (1993) Why Pentose- and Not Hexose-Nucleic Acids? Part III. O1igo(2,3,- dideoxy-β-D-glucopyranosyl) nucleotides. (‘Homo-DNA’): Base-Pairing Properties, Helv. Chim. Acta 76, 259–352.
Otting, G., Billeter, M., Wüthrich, K., Roth, H-J., Leumann, C, and Eschenmoser, A. (1993) Why Pentose- and Not Hexose-Nucleic Acids? Part IV. ’Homo-DNA’: 1H-, 13C-, 31P, -and 15N-NMR-Spectroscopic Investigation of ddGlc (A-A-A-A-A-T-T-T-T-T) in Aqueous Solution, Helv. Chim. Acta 76, 2701–2756.
Eschenmoser, A. (1993) Toward a Chemical Etiology of the Natural Nucleic Acids’ Structure, Proc. R.A. Welch Foundation Conferences on ’Chemical Research XXXVH: 40 Years of DNA Double Helix’, Houston, Texas, pp. 201–235.
Pitsch, S., Wendeborn, S., Jaun, B., and Eschenmoser, A. (1993) Why Pentoseand Not Hexose-Nucleic Acids? Part VII. Pyranosyl-RNA (′p-RNA), Helv. Chim. Acta 76, 2161–2183.
Dickerson, R.E. (1985) Helix Polymorphism and Information How in DNA, Proc. R.A. Welch Foundation Conferences on ‘Chemical Research XXIX. Genetic Chemistry: The Molecular Basis of Heredity’, pp. 39–75.
Groebke, K. (1993) Über Purin-Purin-Paarungen bei Hexopyranose-Nukleinsäuren, Thesis No. 10149, ETH Zürich.
Fraser, W. (1992) unpublished work, ETH Zürich.
Holzner, A. (1993) unpublished work, ETH Zürich.
Fischer, R.W. (1992) Allopyranosyl-Nukleinsaure: Synthese, Paarungseigenschaften und Struktur von Adenin-/Uracil-haltigen Oligonukleotiden, Thesis No. 9971, ETH Zürich.
Helg, A. (1994) Allopyranosyl-Nukleinsäure: Synthese, Paarungseigenschaften und Struktur von Guanin-/Cytosin-enthaltenden Oligonukleotiden, Thesis No. 10464, ETH Zürich.
Hammer, R. (1992) unpublished work, ETH Zürich.
Krishnamurthy, R. (1994) unpublished work, ETH Zürich.
Eschenmoser, A. (1993) Hexose nucleic acids, Pure & Appl. Chem. 65, 1179–1188.
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Eschenmoser, A. (1996). Towards a Chemical Etiology of the Natural Nucleic Acids’ Structure. In: Chatgilialoglu, C., Snieckus, V. (eds) Chemical Synthesis. NATO ASI Series, vol 320. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0255-8_13
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