Abstract
Watson and Crick discovered the DNA double helix in 1953 and realised immediately that its replication involved a templated synthesis.[1] Their work inspired Todd[2] to issue this challenge in 1956:
“The use of one molecule as a template to guide and facilitate the synthesis of another...... has not hitherto been attempted in laboratory synthesis, although it seems probable that it is common in living systems. It represents a challenge which must, and surely can, be met by organic chemistry.”
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References
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© 1996 Kluwer Academic Publishers
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Anderson, S., Sanders, J.K.M. (1996). Templated Synthesis of Enzyme Mimics: How Far can We Go?. In: Chatgilialoglu, C., Snieckus, V. (eds) Chemical Synthesis. NATO ASI Series, vol 320. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0255-8_12
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DOI: https://doi.org/10.1007/978-94-009-0255-8_12
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