Abstract
Lymphoproliferative disorders are the major neoplastic complications in acquired immunosuppressed patients after organ transplantation or HIV infection. Post transplantation lymphoproliferative disorders (PTLDs) affect approximately 2% of all organ recipients [1]. Non Hodgkin’s lymphomas (NHL) arise at the time of the onset of acquired immunodeficiency syndrome (AIDS) in 3% of HIV infected patients and 10% of AIDS patients will develop a NHL [2].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Penn I. The changing pattern of postransplant malignancies. Transplant Proc 1991; 23: 1101–1103.
Beral V, Peterman T, Berkelman R, Jaffe H. AIDS-associated non Hodgkin’s lymphoma. Lancet 1991; 337: 805–809.
Hamilton-Dutoit SJ, Raphael M, Audouin J et al. In situ demonstration of Epstein-Barr virus small RNAs (EBER 1) in acquired immunodeficiency syndrome-related lymphomas: correlation with tumor morphology and primary site. Blood 1993; 82: 619–624.
Craig FE, Gulley ML, Banks P. Posttransplantation lymphoproliferative disorders. Am J Clin Pathol 1993; 99: 265–276.
Swerdlow SH. Post-transplant lymphoproliferative disorders: a morphologic phenotypic and genotypic spectrum of disease. Histopathology 1992; 20: 373–385.
Locker J, Nalesnik M. Molecular genetic analysis of lymphoid tumors arising after transplantation. Am J Pathol 1989; 135: 977–987.
Frizzera G, Hanto DW, Galj-Peczalska KJ et al. Polymorphic diffuse B-cell hyperplasia and lymphomas in renal transplant recipients. Cancer Res 1981; 41: 4262–4271.
Leblond V, Sutton L, Dorent R et al. Lymphoproliferative disorders after organ transplantation: a report of 24 cases observed in a single center. J Clin Oncol 1995; 13: 961–968.
Thomas JA, Hochin NA, Allday MJ et al. Immunohistology of Epstein-Barr-associated antigens in B-cell disorders from immunocompromised individuals. Transplantation 1990; 49: 944–953.
Young L, Alfieri C, Hennessy K et al. Expression of Epstein-Barr virus transformation- associated genes in tissues of patients with EBV lymphoproliferative disease. N Engl J Med 1989; 321: 1080–1085.
Rea D, Fourcade C, Leblond V et al. Patterns of Epstein-Barr virus latent and replicative gene expression in Epstein-Barr virus-B-cell lymphoproliferative disorders after organ transplantation. Transplantation 1994; 58: 317–324.
Knowles D. Post-transplantation lymphoproliferative disorders. Am J Surg Pathol 1994; 18(2): 208–210.
Raphaël M, Audouin J, Lamine M et al. Immunophenotypic and genotypic analysis of acquired immunodeficiency syndrome-related non-Hodgkin’s lymphomas. Am J Clin Pathol 1994; 101: 773–782.
Raphaël M, Genthilomme O, Tulliez M, Bryon PA, Diebold J and the French Study Group of Pathology for HIV-associated Tumors. Histopathologic features of high grade non-Hodgkin’s lymphomas in acquired immunodeficiency syndrome. Arch Pathol Lab med 1991; 115: 15–20.
Raphael M, Audouin J, Tulliez M et al. Anatomic and histologic distribution of 448 cases of AIDS-related non Hodgkin’s lymphomas. Blood 1993; 82: 56a.
Delecluse HJ, Raphael M, Magaud JP et al. Variable morphology of human immunodeficiency virus-associated lymphomas with the c-myc rearrangements. Blood 1993; 82: 552–563.
Ballerini P, Gaidano G, Gong JZ et al. Multiple genetic lesions in acquired immunodeficiency syndrome-related nonHodgkin’s lymphoma. Blood 1993; 81: 166–173.
Camilleri-Broët S, Davi F, Feuillard J, Bourgeois C, Seilhan D, Hauw JJ, Raphaël M. High expression of latent membrane protein 1 (LMP1) of Epstein-Barr virus and bcl2 oncoprotein in AIDS-related primary brain lymphomas. Blood 1995 (in press).
Cesarman E, Chang Y, Moore P, Said JW, Knowles D. Kaposi’s sarcoma-associated herpes virus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med 1995; 332: 1186–1191.
Prevot S, Audouin J, Raphael M, Le Charpentier Y, Michiels JF, Diebold J. Association of HIV1-related hodgkin’s disease with Epstein-Barr Virus. Cold Spring Harbor Meeting on Cancer Cells. Epstein-Barr virus and Associated Diseases 1994 Sept 7–11.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Kluwer Academic Publishers
About this chapter
Cite this chapter
Raphael, M., Camilleri-Broet, S., Davi, F., Martin, A., Prevot, S., Feuillard, J. (1996). Types of lymphomas in transplant and other immunosuppressed patients. In: Touraine, J.L., Traeger, J., Bétuel, H., Dubernard, J.M., Revillard, J.P., Dupuy, C. (eds) Cancer in Transplantation: Prevention and Treatment. Transplantation and Clinical Immunology, vol 27. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0175-9_24
Download citation
DOI: https://doi.org/10.1007/978-94-009-0175-9_24
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6563-4
Online ISBN: 978-94-009-0175-9
eBook Packages: Springer Book Archive