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Human T-cell leukemia virus type I (HTLV-I) and transplantation

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Cancer in Transplantation: Prevention and Treatment

Part of the book series: Transplantation and Clinical Immunology ((TRAC,volume 27))

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Abstract

Human T-cell leukemia virus type I (HTLV-I) [1] is a retrovirus unevenly distributed around the World. The main endemic regions are southwestern Japan, intertropical Africa, the Caribbean and South America [2,3]. HTLV-I is the causative agent of Adult T cell leukemia/lymphoma (ATL) [4] and of Tropical spastic paraparesisl HTLV-I associated myelopathy (TSP/HAM) [5]. However, only a small proportion (1 to 5%) of HTLV-I infected individuals will develop an ATL or a TSP/HAM, and the majority of the infected patients remain asymptomatic for their entire life. The biological features of HTLV-I associated syndromes are summarized in Table 1.

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© 1996 Kluwer Academic Publishers

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Bazarbachi, A., Gessain, A. (1996). Human T-cell leukemia virus type I (HTLV-I) and transplantation. In: Touraine, J.L., Traeger, J., Bétuel, H., Dubernard, J.M., Revillard, J.P., Dupuy, C. (eds) Cancer in Transplantation: Prevention and Treatment. Transplantation and Clinical Immunology, vol 27. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0175-9_11

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  • DOI: https://doi.org/10.1007/978-94-009-0175-9_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6563-4

  • Online ISBN: 978-94-009-0175-9

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