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Optical Spectroscopy and Computational Methods in Biology and Medicine pp 309–326Cite as

Structural and Spatial Analysis of Carotenoids in a Single Cell Monitored by Raman Spectroscopy

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Part of the book series: Challenges and Advances in Computational Chemistry and Physics ((COCH,volume 14))

Abstract

Carotenoids are particularly convenient subjects to study by means of Raman spectroscopy due to very high Raman scattering cross-section associated with their chain vibrations. Raman studies of carotenoids in single cells have a variety of applications starting from monitoring of growth and morphogenesis of unicellular algae and ending with differentiation of cancerous versus non-cancerous tissues in humans. Examples illustrating the potential of Raman spectroscopy to investigate carotenoids structure and distribution with a particular impact on studies using chemometric and computational methods as a tool to analyze experimental data are reviewed in this chapter.

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Author information

Authors and Affiliations

  1. Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060, Krakow, Poland

    Agnieszka Kaczor & Marta Pilarczyk

  2. Jagiellonian Centre of Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, 30-348, Krakow, Poland

    Agnieszka Kaczor

Authors
  1. Agnieszka Kaczor
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  2. Marta Pilarczyk
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Correspondence to Agnieszka Kaczor .

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Editors and Affiliations

  1. Faculty of Chemistry, Jagiellonian University, Ingardena 3, Krakow, Poland

    Malgorzata Baranska

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Kaczor, A., Pilarczyk, M. (2014). Structural and Spatial Analysis of Carotenoids in a Single Cell Monitored by Raman Spectroscopy. In: Baranska, M. (eds) Optical Spectroscopy and Computational Methods in Biology and Medicine. Challenges and Advances in Computational Chemistry and Physics, vol 14. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7832-0_11

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