Abstract
Among the many types of spinal fractures reported, thoracolumbar fracture is the most common; it is characterized by medullary cone injury, functional impairment of the sensory and motor nerves and atonic bladder [1–3]. Atonic bladder leads to severe urinary retention, refractory urinary infections, and even chronic renal failure, making it the main cause of death from medullary injury [4, 5]. Therefore, it is important to restore self-controlled urination in these patients, in order to decrease the mortality rate and improve their quality of life.
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References
Benevento BT, Sipski ML. Neurogenic bladder, neurogenic bowel, and sexual dysfunction in people with spinal cord injury. Phys Ther. 2002;82:601–12.
Dogan S, Safavi-Abbasi S, Theodore N, Chang SW, Horn EM, Mariwalla NR, et al. Thoracolumbar and sacral spinal injuries in children and adolescents: a review of 89 cases. J Neurosurg. 2007;106:426–33.
Heary RF, Salas S, Bono CM, Kumar S. Complication avoidance: thoracolumbar and lumbar burst fractures. Neurosurg Clin N Am. 2006;17:377–88.
Blok BF, Karsenty G, Corcos J. Urological surveillance and management of patients with neurogenic bladder: results of a survey among practicing urologists in Canada. Can J Urol. 2006;13:3239–43.
Samson G, Cardenas DD. Neurogenic bladder in spinal cord injury. Phys Med Rehabil Clin N Am. 2007;18:255–74.
Chuang DC, Chang PL, Cheng SY. Root reconstruction for bladder reinnervation: an experimental study in rats. Microsurgery. 1991;12:237–45.
Sundin T, Carlsson CA. Reconstruction of severed dorsal roots innervating the urinary bladder. An experimental study in cats. II. Regeneration studies. Scand J Urol Nephrol. 1972;6:185–96.
Xiao CG, Godec CJ. A possible new reflex pathway for micturition after spinal cord injury. Paraplegia. 1994;32:300–7.
Lin H, Hou C, Chen A, Xu Z. Innervation of reconstructed bladder above the level of spinal cord injury for inducing micturition by contractions of the abdomen – to – bladder reflex arc. Neurosurgery. 2010;66:948–52.
Lin H, Hou CL, Zhong G, Xie Q, Wang S. Reconstruction of reflex pathways to the atonic bladder after conus medullaris injury: preliminary clinical results. Microsurgery. 2008;28(6):429–35.
Hiersemenzel LP, Curt A, Dietz V. From spinal shock to spasticity: neuronal adaptations to a spinal cord injury. Neurology. 2000;54:1574–82.
Storch JS. Lumbar burst fracture associated with bowel, bladder, and sexual dysfunction: case study. J Neurosci Nurs. 2005;37:68–71.
Dahlberg A, Perttilä I, Wuokko E, Ala-Opas M. Bladder management in persons with spinal cord lesion. Spinal Cord. 2004;42:694–8.
Hirsch NP. Neuromuscular junction in health and disease. Br J Anaesth. 2007;99:132–8.
Kobayashi H, Yamataka A, Lane GJ, Miyano T. Disseminated mixed intestinal dysmotility (DMID): a new intestinal ganglion cell disorder? Pediatr Surg Int. 2005;21:883–8.
Pirker ME, Rolle U, Shinkai T, Shinkai M, Puri P. Prenatal and postnatal neuromuscular development of the ureterovesical junction. J Urol. 2007;177:1546–51.
Burnstock G. Innervation of bladder and bowel. Ciba Found Symp. 1990;151:2–18.
Fry CH, Hussain M, McCarthy C, Ikeda Y, Sui GP, Wu C. Recent advances in detrusor muscle function. Scand J Urol Nephrol Suppl. 2004;215:20–5.
Hashitani H, Bramich NJ, Hirst GD. Mechanisms of excitatory neuromuscular transmission in the guinea-pig urinary bladder. J Physiol. 2000;524:565–79.
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Zheng, X., Hou, C. (2014). Pathological Changes in the Detrusor After Spinal Cord Injury. In: Hou, C. (eds) Functional Bladder Reconstruction Following Spinal Cord Injury via Neural Approaches. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7766-8_4
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DOI: https://doi.org/10.1007/978-94-007-7766-8_4
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