Abstract
Mesenchymal chondrosarcoma is a rare malignant neoplasm typically arising in the bones of young adults. It may also arise in somatic soft tissue, central nervous system and other organs. There are no specific clinical or radiological characteristics, and histological assessment remains the key to diagnosis. Histological features are similar regardless of site, and display a characteristic biphasic pattern composed of highly undifferentiated small round cells and islands of well differentiated hyaline cartilage. In this chapter, we discuss the clinical, radiological and histological features of mesenchymal chondrosarcoma arising in the central nervous system (CNS), the important differential diagnoses of small round cell tumour within the CNS, and the differentiating features of mesenchymal chondrosarcoma from Ewing sarcoma/PNET, medulloblastoma, haemangiopericytoma, monophasic synovial sarcoma and atypical teratoid/rhabdoid tumour.
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Lin, L., Varikatt, W., Ng, T. (2014). Mesenchymal Chondrosarcoma in the Central Nervous System: Histological Diagnosis. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 13. Tumors of the Central Nervous System, vol 13. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7602-9_7
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DOI: https://doi.org/10.1007/978-94-007-7602-9_7
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