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Metastatic Oligodendroglioma: Diagnosis with Fine-Needle Aspiration Cytology

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Tumors of the Central Nervous System, Volume 13

Part of the book series: Tumors of the Central Nervous System ((TCNS,volume 13))

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Abstract

Extracranial/systemic metastasis of a primary central nervous system glial tumor is very rare, but the incidence is ever-increasing. Oligodendroglial tumors are uncommon; however, after high-grade astrocytomas, they constitute an important group of tumors which are reported to cause extracranial metastases. In the majority of literature-reported cases, the likelihood of a second primary tumor is considered as the first approach; therefore metastases are overlooked. Fine-needle aspiration cytology (FNAC) is currently accepted as a reliable, accurate, cost-effective and rapid diagnostic method for possible metastatic lesions in a patient with known primary tumor. FNAC findings of metastatic oligodendroglioma and small-round-cell tumors (SRCT) are quite similar, therefore differential diagnosis requires combination of the clinical and radiological data. In addition, application of immunochemistry and detection of 1p/19q co-deletion on cytological material confirm the diagnosis.

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Authors and Affiliations

  1. Department of Pathology, School of Medicine, Ondokuz Mayis University, 55139, Samsun, Turkey

    Bilge Can Meydan & İlkser Akpolat

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  1. Bilge Can Meydan
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  2. İlkser Akpolat
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Correspondence to Bilge Can Meydan .

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Editors and Affiliations

  1. Department of Biological Sciences, Kean University, Room 213, Library Building, Union, New Jersey, USA

    M.A. Hayat

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Meydan, B.C., Akpolat, İ. (2014). Metastatic Oligodendroglioma: Diagnosis with Fine-Needle Aspiration Cytology. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 13. Tumors of the Central Nervous System, vol 13. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7602-9_3

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  • DOI: https://doi.org/10.1007/978-94-007-7602-9_3

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-7601-2

  • Online ISBN: 978-94-007-7602-9

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