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Selected References
Bailey LH (1949) Manual of cultivated plants most commonly grown in the continental United States and Canada, revised edn. The Macmillan Co., New York, 1116pp
Baruah RN, Leclercq PA (1993) Characterization of the essential oil from flower heads of Spilanthes acmella. J Essent Oil Res 5(6):693–695
Baruah RN, Pathak MG (1999) Hydrocarbons from the flower heads of Spilanthes acmella. J Med Aromat Plant Sci 21(3):675–676
Belfer WA (2009) Cosmetic composition to accelerate repair of functional wrinkles. US Patent US8025907
Benwick BS (2007) Like a taste that tingles? Then this bud is for you. Washington Post. http://www.washingtonpost.com/wp-dyn/content/article/2007/10/02/AR2007100200464.html
Boonen J, Baert B, Burvenich C, Blondeel P, De Saeger S, De Spiegeleer B (2010a) LC-MS profiling of N-alkylamides in Spilanthes acmella extract and the transmucosal behaviour of its main bio-active spilanthol. J Pharm Biomed Anal 53(3):243–249
Boonen J, Baert B, Roche N, Burvenich C, De Spiegeleer B (2010b) Transdermal behaviour of the N-alkylamide spilanthol (affinin) from Spilanthes acmella (Compositae) extracts. J Ethnopharmacol 127(1):77–84
Boonen J, Bronselaer A, Nielandt J, Veryser L, Tré GD, De Spiegeleer B (2012) Alkamid database: chemistry, occurrence and functionality of plant N-alkylamides. J Ethnopharmacol 142(3):563–590
Bosch CH (2004) Acmella oleracea (L.) R.K.Jansen. [Internet] Record from protabase. In: Grubben GJH, Denton OA (eds) PROTA (Plant resources of tropical Africa/Ressources végétales de l′Afrique tropicale). Wageningen. http://database.prota.org/search.htm. Accessed 29 Apr 2012
Burdock GA (2010) Fenaroli’s handbook of flavor ingredients, 5th edn. CRC Press, Boca Raton, 1864pp
Burkill IH (1966) A dictionary of the economic products of the Malay Peninsula, revised reprint, 2 vols. Ministry of Agriculture and Co-operatives, Kuala Lumpur, vol 1 (A–H), pp 1–1240, vol 2 (I–Z), pp 1241–2444
Chakraborty A, Devi BR, Sanjebam R, Khumbong S, Thokchom IS (2010) Preliminary studies on local anesthetic and antipyretic activities of Spilanthes acmella Murr. in experimental animal models. Indian J Pharmacol 42(5):277–279
Council of Scientific and Industrial Research (1976) The wealth of India. A dictionary of Indian raw materials and industrial products, Raw materials 10. Publications and Information Directorate, New Delhi
de Padua LS, Lugod GC, Pancho JV (1977–1983) Handbook on Philippine medicinal plants, 4 vols. Documentation and Information Section, Office of the Director of Research, University of the Philippines at Los Banos
Deane G (2007–2012) Edible flowers: part thirteen. http://www.eattheweeds.com/edible-flowers-part-thriteen
Demarne F, Passaro G (2005) Use of an Acmella oleracea extract for its botox-like effect in an antiwrinkle cosmetic composition. FR Patent 286513
Dias AMA, Santos P, Seabra IJ, Júnior RNC, Braga MEM, de Sousa HC (2012) Spilanthol from Spilanthes acmella flowers, leaves and stems obtained by selective supercritical carbon dioxide extraction. J Supercrit Fluids 61:62–70
Ekanem AP, Wang M, Simon JE, Moreno DA (2007) Antiobesity properties of two African plants (Afromomum meleguetta and Spilanthes acmella) by pancreatic lipase inhibition. Phytother Res 21(12):1253–1255
Gasquet M, Delmas F, Timon-David P, Keita A, Guindo M, Koita N, Diallo D, Doumbo O (1993) Evaluation in vitro and in vivo of a traditional antimalarial, “Malarial 5”. Fitoterapia 64(5):423–426
Greger H, Hofer O, Werner A (1985) New amides from Spilanthes oleraceae. Monatsh Chem 116(2):273–277
Hind N, Biggs N (2003) Plate 460. Acmella oleracea Compositae. Curtis’s Bot Mag 20(1):31–39
Jacobson M (1957) The structure of spilanthol. Chemistry and industry, pp 50–51
Jansen RK (1985) The systematics of Acmella (Asteraceae – Heliantheae). Syst Bot Monogr 8:1–115
Jardin C (1970) List of foods used in Africa. Nutrition information documents, series 2, 2nd edn., rev. FAO, Rome, 328pp
Jirovetz L, Buchbauer G, Wobus A, Shafi MP, Abraham GT (2005) Essential oil analysis of Spilanthes acmella Murr. fresh plants from southern India. J Essent Oil Res 17(4):429–431
Kadir HA, Zakaria MB, Kechil AA, Azirun MS (1989) Toxicity and electrophysiological effects of Spilanthes acmella Murr. extracts on Periplaneta americana L. Pestic Sci 25:329–335
Katzer G (2002) Paracress (Spilanthes acmella Murr. and Spilanthes oleracea L.). http://www.uni-graz.at/~katzer/engl/Spil_acm.html
Kawaree R, Okonogi S, Phutdhawong W (2008) Chemical composition and antioxidant evaluation of volatile oils from Thai medicinal plants. Acta Hortic 786:209–215
Krishnaswamy NR, Prasanna S, Seshadri TR, Vedantham TNC (1975) α- and β-amyrin esters and sitosterol glucoside from Spilanthes acmella. Phytochemistry 14(7):1666–1667
Lemos TLG, Pessoa ODL, Matos FJA, Alencar JW, Craveiro AA (1991) The essential oil of Spilanthes acmella Murr. J Essent Oil Res 3(5):369–370
Ley JP, Blings M, Krammer G, Reinders G, Schmidt CO, Bertram HJ (2006) Isolation and synthesis of acmellonate, a new unsaturated long chain 2-ketol ester from Spilanthes acmella. Nat Prod Res 20(9):798–804
Lion Corporation (1985) Dentifrices containing spilanthols and spice extracts. Lion Corporation Japan, Japan Kokai Tokkyo Koho
Mbeunkui F, Grace MH, Lategan C, Smith PJ, Raskin I, Lila MA (2011) Isolation and identification of antiplasmodial N-alkylamides from Spilanthes acmella flowers using centrifugal partition chromatography and ESI-IT-TOF-MS. J Chromatogr B Analyt Technol Biomed Life Sci 879(21):1886–1892
Moreira VM, Maia JG, de Souza JM, Bortolotto ZA, Cavalheiro EA (1989) Characterization of convulsions induced by a hexanic extract of Spilanthes acmella var. oleracea in rats. Braz J Med Biol Res 22(1):65–67
Moreno SC, Carvalho GA, Picanço MC, Morais EG, Pereira RM (2012) Bioactivity of compounds from Acmella oleracea against Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) and selectivity to two non-target species. Pest Manag Sci 68(3):386–393
Nagashima M, Nakatani N (1992a) LC-LS analysis and structure determination of pungent alkamides from Spilanthes acmella L. flowers. Lebensm Wiss Technol 25(1):417–421
Nagashima M, Nakatani N (1992b) Two sesquiterpenes from Spilanthes acmella L. Chem Express 6(12):993–996
Nakatani N, Nagashima M (1992) Pungent alkamides from Spilanthes acmella var. oleracea Clarke. Biosci Biotechnol Biochem 56(5):759–762
Nascimento AM, de Souza LM, Baggio CH, Werner MF, Maria-Ferreira D, da Silva LM, Sassaki GL, Gorin PA, Iacomini M, Cipriani TR (2013) Gastroprotective effect and structure of a rhamnogalacturonan from Acmella oleracea. Phytochemistry 85:137–142
Ochse JJ, Bakhuizen van den Brink RC (1980) Vegetables of the Dutch Indies, 3rd edn. Ascher & Co, Amsterdam, 1016pp
Pandey V, Agrawal V, Raghavendra K, Dash AP (2007) Strong larvicidal activity of three species of Spilanthes (Akarkara) against malaria (Anopheles stephensi Liston, Anopheles culicifacies, species C) and filaria vector (Culex quinquefasciatus Say). Parasitol Res 102(1):171–174
Pandey V, Chopra M, Agrawal V (2011) In vitro isolation and characterization of biolarvicidal compounds from micropropagated plants of Spilanthes acmella. Parasitol Res 108(2):297–304
Patiri B, Borah A (2007) Wild edible plants of Assam. Geetakhi Printers and Publishers, Guwahati
Peiris KPP, Silva GKJ, Ratnasooriya WD (2001) Analgesic activity of water extract of Spilanthes acmella flowers on rats. J Trop Med Plants 2(2):120–126
Pitasawat B, Choochote W, Kanjanapothi D, Panthong A, Jitpakdi A, Chaithong U (1998) Screening for larvicidal activity of ten carminative plants. Southeast Asian J Trop Med Public Health 29(3):660–662
Prachayasittikul S, Suphapong S, Worachartcheewan A, Lawung R, Ruchirawat S, Prachayasittikul V (2009) Bioactive metabolites from Spilanthes acmella Murr. Molecules 14(2):850–867
Prasad MM, Seenayya G (2000) Effects of spices on growth of red halophilic cocci isolated from salt cured fish and solar salt. Food Res Int 33(9):793–798
Ramsewak RS, Erickson AJ, Nair MG (1999) Bioactive N-isobutylamides from the flower buds of Spilanthes acmella. Phytochemistry 51(6):729–732
Raner GM, Cornelious S, Moulick K, Wang Y, Mortenson A, Cech NB (2007) Effects of herbal products and their constituents on human cytochrome P450(2E1) activity. Food Chem Toxicol 45(12):2359–2365
Rani SA, Murty SU (2006) Antifungal potential of flower head extract of Spilanthes acmella. Afr J Biomed Res 9:67–69
Ratnasooriya WD, Pieris KP, Samaratunga U, Jayakody JR (2004) Diuretic activity of Spilanthes acmella flowers in rats. J Ethnopharmacol 91(2–3):317–320
Roemantyo (1994) Spilanthes Jacquin. In: Siemonsma JS, Piluek K (eds) Plant resources of South-East Asia, No. 8. Vegetables Pudoc, Wageningen, pp 264–266
Saraf DK, Dixit VK (2002) Spilanthes acmella Murr: study on its extract spilanthol as larvicidal compound. Asian J Exp Sci 16(1&2):9–19
Savadi RV, Yadav R, Yadav N (2010) Study on immunomodulatory activity of ethanolic extract of Spilanthes acmella Murr. leaves. Indian J Nat Prod Res 1(2):204–207
Sharma V, Boonen J, Chauhan NS, Thakur M, De Spiegeleer B, Dixit VK (2011) Spilanthes acmella ethanolic flower extract: LC-MS alkylamide profiling and its effects on sexual behavior in male rats. Phytomedicine 18(13):1161–1169
Shimada T, Gomi T (1995) Spilanthol-rich essential oils for manufacturing toothpastes or other oral compositions. JP Patent 07090294
Simas NK, Lima Dellamora ECL, Schripsema J, Lage CLS, de Oliveira Filho AM, Wessjohann L, Porzel A, Kuster RM (2013) Acetylenic 2-phenylethylamides and new isobutylamides from Acmella oleracea (L.) R. K. Jansen, a Brazilian spice with larvicidal activity on Aedes aegypti. Phytochem Lett 6(1):67–72
Singh M, Chaturvedi R (2012) Screening and quantification of an antiseptic alkylamide, spilanthol from in vitro cell and tissue cultures of Spilanthes acmella Murr. Ind Crop Prod 36(1):321–328
Smith AC (1991) Flora Vitiensis nova: a new flora of Fiji, vol 5. National Tropical Botanical Garden, Lawai, 626pp
Spelman K, Depoix D, McCray M, Mouray E, Grellier P (2011) The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo antimalarial activity. Phytother Res 25(7):1098–1101
Tan CL, Ning SP, Boey PL, Chan LK (2011) Detection of bioactive compounds from Spilanthes acmella (L.) plants and its various in vitro culture products. J Med Plant Res 5(3):371–378
Tanwer BS, Choudhary RK, Vijayvergia R (2010) In vitro and in vivo comparative study of primary metabolites and antioxidant activity in Spilanthes acmella. Int J Biotechnol Biochem 6(5):819–825
Tiwari HP, Kakkar A (1990) Phytochemical examination of Spilanthes acmella Murr. J Indian Chem Soc 67(9):784–785
Toothman C (2009) It’s shocking, but you eat it. NPR. http://www.npr.org/templates/story/story.php?storyId=101304548&ft=1&f=1007
Wetwitayaklung P, Phaechamud T, Limmatvapirat C, Keokitichai S (2008) The study of antioxidant activities of edible flower extracts. Acta Hortic (ISHS) 786:185–192
Wongsawatkul O, Prachayasittikul S, Isarankura-Na-Ayudhya C, Satayavivad J, Ruchirawat S, Prachayasittikul V (2008) Vasorelaxant and antioxidant activities of Spilanthes acmella Murr. Int J Mol Sci 9(12):2724–2744
Wu LC, Fan NC, Lin MH, Chu IR, Huang SJ, Hu CY, Han SY (2008) Anti-inflammatory effect of spilanthol from Spilanthes acmella on murine macrophage by down-regulating LPS-induced inflammatory mediators. J Agric Food Chem 56(7):2341–2349
Yadav R, Kharya DM, Yadav N, Savadi R (2011a) Immunomodulatory potential of ethanol extract of Spilanthus acmella leaves. Int J Biol Med Res 2(3):631–635
Yadav R, Yadav N, Kharya MD, Savadi R (2011b) Preliminary studies on diuretic effect of Spilanthes acmella leaves extracts in rats. Int J Pharm Pharm Sci 3(3):245–247
Yasuda I, Takeya K, Itokawa H (1980) The geometric structure of spilanthol. Chem Pharm Bull 28(7):2251–2253
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Lim, T.K. (2014). Acmella oleracea. In: Edible Medicinal And Non-Medicinal Plants. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7395-0_11
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