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Molluscan Shellfish Safety pp 239–248Cite as

Histopathological Alterations of the Mantle of Mytilus galloprovincialis from the Ria of Vigo (NW Spain): Effect of Persistent Chemicals?

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Abstract

The present study describes the occurrence of neoplastic disorders in the gonad (mantle tissue) of Mytilus galloprovincialis in relation to persistent chemicals accumulation. Germinal cells are the main cellular type affected by these neoplastic alterations. The neoplastic prevalence was 18 %, being higher in males (62.5 %) than in females (37.5 %), with a higher incidence during periods of active gametogenesis. Persistent environmental pollutants such as PAHs, organochlorine compounds (PCBs and OCPs) and trace elements were also analyzed in mussel samples. A high correlation between neoplastic prevalence and PAH’s of high molecular weight, dioxin-like PCB’s, Cd and Zn was observed. Multivariate analysis suggests possible synergic effects between these mutagenic species in the promotion and progress of described neoplastic disorders, as well as their lethal effect of high accumulated concentrations.

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Acknowledgment

The authors thank Antonio Antepazos and the fishermen of the “Antepazos I”, who kindly provided the mussels used in this work. Furthermore, we would like to thank to the Spanish Institute of Oceanography from Vigo (IEO), contracted for the determination of contaminants. This work was supported by a grant from Autonomous Galician Government (PGIDT10MDS312030PR).

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Authors and Affiliations

  1. Department of Biochemistry, Genetics and Immunology, University of Vigo, Vigo, Spain

    Y. Ruiz, P. Suárez, A. Vidal & F. San Juan

  2. Department of Biochemistry, Genetics and Immunology, Faculty of Sciences, University of Vigo, Lagoas-Marcosende s/n., 36310, Vigo, Spain

    Ana Alonso Martinez

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  1. Y. Ruiz
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  2. P. Suárez
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  3. Ana Alonso Martinez
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  4. A. Vidal
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  5. F. San Juan
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Correspondence to Y. Ruiz .

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  1. Canadian Food Inspection Agency, Ottawa, Ontario, Canada

    Gilbert Sauvé

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Ruiz, Y., Suárez, P., Martinez, A.A., Vidal, A., Juan, F.S. (2014). Histopathological Alterations of the Mantle of Mytilus galloprovincialis from the Ria of Vigo (NW Spain): Effect of Persistent Chemicals?. In: Sauvé, G. (eds) Molluscan Shellfish Safety. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6588-7_21

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