Skip to main content
SpringerLink
Log in
Book cover

Angiogenesis Modulations in Health and Disease pp 199–203Cite as

Speculations on New Directions in Which Angiogenesis May Proceed

  • Chapter
  • First Online:

  • 814 Accesses

Abstract

Angiogenesis regulation is a function of pro-angiogenesis and anti-angiogenesis factors and processes. These include growth factors, cell surface receptors for these factors on blood vessel cells, modulatory crosstalk between growth factor receptors and other cell surface proteins such as integrin αvβ3, and transduction of growth factor signals into a modified angiogenesis process. In this chapter we consider areas of blood vessel growth control in which we can expect new information in the near future.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Clauss M (2000) Molecular biology of the VEGF and VEGF receptor family. Semin Thromb Hemost 26(5):561–569

    Article  PubMed  CAS  Google Scholar 

  2. Alvarez-Garcia V, Gonzalez A, Alonso-Gonzalez C, Martinez-Campa C, Cos S (2012) Regulation of vascular endothelial growth factor by melatonin in human breast cancer cells. J Pineal Res 54(4):373–380

    Google Scholar 

  3. Yang J, McNeish B, Butterfield C, Moses MA (2013) Lipocalin 2 is a novel regulator of angiogenesis in human breast cancer. FASEB J 27(1):45–50

    Google Scholar 

  4. Chen Y, Fu L, Han Y, Teng Y, Sun J, Xie R, Cao J (2012) Testosterone replacement therapy promotes angiogenesis after acute myocardial infarction by enhancing expression of cytokines HIF-1alpha, SDF-1alpha and VEGF. Eur J Pharmacol 684(1–3):116–124

    Article  PubMed  CAS  Google Scholar 

  5. Ribatti D (2010) Erythropoietin and tumor angiogenesis. Stem Cells Div 19(1):1–4

    Article  CAS  Google Scholar 

  6. Davis PJ, Davis FB, Mousa SA, Luidens MK, Lin HY (2011) Membrane receptor for thyroid hormone: physiologic and pharmacologic implications. Annu Rev Pharmacol Toxicol 51:99–115

    Article  PubMed  CAS  Google Scholar 

  7. Mikula-Pietrasik J, Kuczmarska A, Kucinska M, Murias M, Wierzchowski M, Winckiwicz M, Staniszewski R, Breborowicz A, Ksiazek K (2012) Resveratrol and its synthetic derivatives exert opposite effects on mesothelial cell-dependent angiogenesis via modulating secretion of VEGF and IL-8/CXCL8. Angiogenesis 15(3):361–376

    Article  PubMed  CAS  Google Scholar 

  8. Kim KH, Bender JR (2009) Membrane-initiated actions of estrogen on the endothelium. Mol Cell Endocrinol 308(1–2):3–8

    Article  PubMed  CAS  Google Scholar 

  9. Lin HY, Cody V, Davis FB, Hercbergs AA, Luidens MK, Mousa SA, Davis PJ (2011) Identification and functions of the plasma membrane receptor for thyroid hormone analogues. Discov Med 11(59):337–347

    PubMed  Google Scholar 

  10. Glinskii AB, Glinsky GV, Lin HY, Tang HY, Sun M, Davis FB, Luidens MK, Mousa SA, Hercbergs AH, Davis PJ (2009) Modification of survival pathway gene expression in human breast cancer cells by tetraiodothyroacetic acid (tetrac). Cell Cycle 8(21):3554–3562

    Article  PubMed  Google Scholar 

  11. Lin HY, Sun M, Tang HY, Lin C, Luidens MK, Mousa SA, Incerpi S, Drusano GL, Davis FB, Davis PJ (2009) L-Thyroxine vs. 3, 5, 3´-triiodo-L-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Am J Physiol Cell Physiol 296(5):C980–C991

    Article  PubMed  CAS  Google Scholar 

  12. Gondou A, Toyoda N, Nishikawa M, Yonemoto T, Sakaguchi N, Tokoro T, Inada M (1999) Effect of nicotine on type 2 deiodinase activity in cultured rat glial cells. Endocr J 46(1):107–112

    Article  PubMed  CAS  Google Scholar 

  13. Sudhagar S, Sathya S, Lakshmi BS (2011) Rapid non-genomic signaling by 17β-oestradiol through c-Src involves mTOR-dependent expression of HIF-1α in breast cancer cells. Br J Cancer 105(7):953–960

    Article  PubMed  CAS  Google Scholar 

  14. Waugh DJ, Wilson C (2008) The interleukin-8 pathway in cancer. Clin Cancer Res 14(21):6735–6741

    Article  PubMed  CAS  Google Scholar 

  15. Volin MV, Koch AE (2011) Interleukin-18: a mediator of inflammation and angiogenesis in rheumatoid arthritis. J Interferon Cytokine Res 31(10):745–751

    Article  PubMed  CAS  Google Scholar 

  16. Wu Y, Li YY, Matushima K, Baba T, Mukaida N (2008) CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process. J Immunol 181(9):6384–6393

    PubMed  CAS  Google Scholar 

  17. Chauhan VP, Stylianopoulos T, Martin JD, Popovic C, Chen O, Kamoun WS, Bawendi MG, Fukumura D, Jain RK (2012) Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nat Nanotechnol 7(6):383–388

    Article  PubMed  CAS  Google Scholar 

  18. Murphy EA, Majeti BK, Barnes LA, Makale M, Weis SM, Lutu-Fuga K, Wrasidlo W, Cheresh DA (2008) Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis. Proc Natl Acad Sci U S A 105(27):9343–9348

    Article  PubMed  CAS  Google Scholar 

  19. Heusschen R, van Gink M, Griffioen AW, Thijssen VL (2010) MicroRNAs in the tumor endothelium: novel controls on the angioregulatory switchboard. Biochim Biophys Acta 1805:87–96

    PubMed  CAS  Google Scholar 

  20. Rayner KJ, Suarez Y, Davalos A, Parathath S, Fitzgerald ML, Tamehiro N, Fisher EA, Moore KJ, Fernandez-Hernando C (2010) MiR-33 contributes to the regulation of cholesterol homeostasis. Science 328:1570–1573

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgement

The authors appreciate the generous investment of Richard C. Liebich in much of the work reported in [6, 9–11] included in this chapter.

Author information

Authors and Affiliations

  1. The Pharmaceutical Research Institute at Albany College of Pharmacy and Health Sciences, Rensselaer, NY, USA

    Shaker A. Mousa & Paul J. Davis

  2. Department of Medicine, Albany Medical Center, Albany, NY, USA

    Paul J. Davis

Authors
  1. Shaker A. Mousa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Paul J. Davis
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shaker A. Mousa .

Editor information

Editors and Affiliations

  1. , Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sc, Discovery Drive One, Rensselaer, 12144, New York, USA

    Shaker A. Mousa

  2. and Health Sciences, Pharmaceutical Research Institute, Albany College of Pharmacy, Discovery Drive 1, Rensselaer, 12144, New York, USA

    Paul J. Davis

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media Dordrecht

About this chapter

Cite this chapter

Mousa, S.A., Davis, P.J. (2013). Speculations on New Directions in Which Angiogenesis May Proceed. In: Mousa, S., Davis, P. (eds) Angiogenesis Modulations in Health and Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6467-5_16

Download citation

Publish with us

Policies and ethics

Search

Navigation