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Proteins and Powders: Technical Developments

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Uniting Electron Crystallography and Powder Diffraction

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Abstract

Protein powder samples offer many technical challenges for powder diffraction experiments and data analysis. Samples are sensitive to radiation damage and the large unit cells lead to severe peak overlaps, creating interesting challenges. Powder diffraction remains as the unique tool to characterize certain polymorphic forms of crystalline proteins.

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Acknowledgements

I am especially grateful to my collaborators in this adventure into protein powder diffraction; Irene Margiolaki, Yves Watier and Andy Fitch and all of the students and colleagues who have carried the work that was summarized here. We thank the ESRF for provision of synchrotron beamtime.

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Authors and Affiliations

  1. European Synchrotron Radiation Facility, 6 rue Jules Horowitz, 220, Grenoble, F-38043, France

    Jonathan P. Wright

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  1. Jonathan P. Wright
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Correspondence to Jonathan P. Wright .

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Editors and Affiliations

  1. , Institute of Physical Chemistry, Johannes Gutenberg University, Welderweg 11, Mainz, 55128, Germany

    Ute Kolb

  2. , School of Pharmacy, University of Reading, Whiteknights, Reading, RG6 6AP, United Kingdom

    Kenneth Shankland

  3. , Department of Materials Engineering, Ben-Gurion University of the Negev, Marcus Family Campus, Beer-Sheva, 84105, Israel

    Louisa Meshi

  4. Inst. Crystallography, Russian Academy of Sciences, Leninskii prospect 59, Moscow, 119333, Russia

    Anatoly Avilov

  5. , Isis Facility, STFC Rutherford Appleton Laboratory, Harwell Science and Innovation Campus, Didcot, OX11 0QX, United Kingdom

    William I.F David

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Wright, J.P. (2012). Proteins and Powders: Technical Developments. In: Kolb, U., Shankland, K., Meshi, L., Avilov, A., David, W. (eds) Uniting Electron Crystallography and Powder Diffraction. NATO Science for Peace and Security Series B: Physics and Biophysics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5580-2_12

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  • DOI: https://doi.org/10.1007/978-94-007-5580-2_12

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  • Print ISBN: 978-94-007-5579-6

  • Online ISBN: 978-94-007-5580-2

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