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Making Sense of Messy Medical Data Through Constructed Charts of Functional Distances

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Managing and Engineering in Complex Situations

Part of the book series: Topics in Safety, Risk, Reliability and Quality ((TSRQ,volume 21))

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Abstract

This chapter explains a technique called constructed cartography that makes maps or diagrams of events that you might not initially consider appropriate for mapping, including various real or imagined manifestations of diseases and our successful and unsuccessful attempts to mitigate those manifestations. The goal is to reveal underlying patterns in messy data. Starting with data in a form where underlying patterns are elusive, a visual summary is constructed. Information is neither created nor destroyed, just transformed into a more useful form. Two fundamental ideas that allow these charts to be constructed – functional distances and multidimensional scaling – are reviewed. This chapter then describes in detail the data that are needed for constructed cartography. A simulation shows that a sample of 35 cases is sufficient to extract 90% of the pattern in a much larger population. Finally, this chapter reviews several diverse instances where the technique has worked well: administrative funding versus successful vaccinations, migrations, metastases, and symptoms of disease. Finally the potential of aligning our attempts to fight diseases as well as our knowledge of how the disease spreads with ways that the disease actually spreads is outlined. Such a test of congruence of efforts can occur at the individual or at population levels. Places where these constructed charts do not line up are places for closer inspection, consideration, effort or training.

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Acknowledgements

The following institutions provided important support: Rockingham Memorial Hospital (RMH), Karolinska Hospital, M.D. Anderson Cancer Center (MDA), Cancer Research UK (CRUK), University College London (UCL), University of Liverpool (UK), Johns Hopkins (JHU), Tata Memorial Cancer Center (Mumbai), Aga Khan Med School (Karachi), Fulbright Commission, NASA, Cray Research Inc. The following helped in making maps of costs: Jennifer McCabe & Drs. David Bernstein & Bill Grant, JMU; Dr. Kathleen Philbin, UTx; Dr. Dave Grembi, Dr. Steward Pollock, Kay Harrison, Mike King, Steve Nelson, Deb Thomson, Carrie Willets & Theresa Yoder (RMH); in making maps of head and neck cancers: Drs. Tom Robbins and Bob Byers, MDA; Dr. David Sidransky, JHU; Dr. Iftikar Sallahudin, Aga Khan; Drs. Ashok Mehta & D.N. Rao, Tata; Drs. James Brown and Julia Woolgar, UK; Drs. Randall Morton & Dev Tandon, NZ; in making maps of breast cancers: Drs. Michael Baum & Jayant Vaidya, CRUK; Dr. Thomas Hatschek, Karolinska; Dr. Ragendra Badwe & I. Mittra, Tata; Dr. Tariq Siddique (Aga Khan); in the visualizations: Dr. David Bernstein and Kurt See, JMU; Scott Klasky, Richard Lutowski, Yunsong Zhu, Rongrong Wu, Drs. Dorothea Wiarda, Tarryn Witten, UTx; in making maps of patients’ and professionals’ perceptions: Drs. Keith Herrin & Charles Stiernberg (UTx), Garland Novosad & Ruth Tornwall (dental hygienists); in maps of migrations: Dr. John Noftsinger, Ken Newbold & Ben Delp, JMU; in making maps of vaccines: Jennifer McCabe, Drs. David Bernstein & Jerry Benson (JMU). Vincent Vander Poorten MD PhD, made valuable comments on an early draft.

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Gray, L. (2013). Making Sense of Messy Medical Data Through Constructed Charts of Functional Distances. In: Kovacic, S., Sousa-Poza, A. (eds) Managing and Engineering in Complex Situations. Topics in Safety, Risk, Reliability and Quality, vol 21. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5515-4_13

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  • DOI: https://doi.org/10.1007/978-94-007-5515-4_13

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-5514-7

  • Online ISBN: 978-94-007-5515-4

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