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Understanding Mechanism of Action of Herbal Drugs in Age Related Degenerative Brain Disorders

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Abstract

In this review, we will briefly introduce preventive strategies represented by selected plants which are also popularly used by different traditional medicines and have scientific evidences of possible alternative therapeutic value for neuroprotection. Among these commonly used in most traditional medicines of China and India are Gingko biloba, Panax ginseng, Curcuma longa, Withania somnifera (WS) etc. In addition, scientific evidences of usefulness of Vitis vinifera (Grapes) as red wine, Coffee sp and Camelia sinensis (Tea) will be discussed. Here, we will also discuss in detail the possible use of WS as potential candidate for treatment of AD. Clinical trials and animal research supported the use of WS for treatment of anxiety, cognitive and neurological disorders, senile dementia, Alzheimer’s (AD) and Parkinson’s disease (PD), and as antioxidant and anti-inflammatory agent. This might be important in suggesting therapeutic implications of WS in neurodegenerative disorders.

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Authors and Affiliations

  1. Faculty of Science, University College of Science, MLS University, 313001, Udaipur, India

    Maheep Bhatnagar, Ayushi Jain, Neha Jaiswal, Chavi Sharma & Pooja Suvalka

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  1. Maheep Bhatnagar
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  2. Ayushi Jain
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  3. Neha Jaiswal
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  4. Chavi Sharma
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Correspondence to Maheep Bhatnagar .

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  1. , Department of Zoology, Banaras Hindu University, Varanasi, 221005, India

    Mahendra K. Thakur

  2. , Department of Molecular Biology, Aarhus University, Gustav Wieds Vej 10-C, Aarhus-C, 8000, Denmark

    Suresh I.S. Rattan

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Bhatnagar, M., Jain, A., Jaiswal, N., Sharma, C., Suvalka, P. (2012). Understanding Mechanism of Action of Herbal Drugs in Age Related Degenerative Brain Disorders. In: Thakur, M., Rattan, S. (eds) Brain Aging and Therapeutic Interventions. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5237-5_11

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