Abstract
Cancer stem cells (CSCs), that are resistant to chemotherapy, are the major obstacle in treatment of different cancers including colorectal cancer. Recently, markers of CSCs have been identified. CD133, CD44, CD166, ALDH1A1, Lgr5, and several other proteins have been proposed as CSC markers. In this review article, we have discussed several therapeutic strategies that may target the self-renewal pathways, miRNAs and other epigenetic modifiers in colon CSCs to arrest and/or regress recurrent colon cancer.
Keywords
- Cancer Stem Cell
- Adenomatous Polyposi Coli
- Adenomatous Polyposi Coli Mutation
- Activate Leukocyte Cell Adhesion Molecule
- Normal Human Colon
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Roy, S., Majumdar, A.P.N. (2012). Colon Cancer Stem Cells: A Therapeutic Target. In: Hayat, M. (eds) Stem Cells and Cancer Stem Cells, Volume 8. Stem Cells and Cancer Stem Cells, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4798-2_20
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DOI: https://doi.org/10.1007/978-94-007-4798-2_20
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