Abstract
A physiologically based model of sleep-wake cycles is used to examine the role of forced wakefulness during shifts on circadian entrainment of permanent shift workers. We demonstrate that forced wakefulness is crucial for entrainment to night and early morning shifts, while on afternoon and late evening shifts entrainment can be achieved simply due to changes in light. We explain this phenomenon by the properties of the human circadian pacemaker which requires non-photic entrainment for its phase advance in the early hours of the night. This finding is important for a better design of shift workers routine in order to decrease sleepiness.
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References
Åkerstedt, T.: Work hours and sleepiness. Neurophysiol Clin 25 (1995) 367–375.
Dinges, D.F.: An overview of sleepiness and accidents. J Sleep Res 4 (1995) 4–11.
Boivin, D.B., Tremblay, G.M., James, F.O.: Working on atypical schedules. Sleep med 8 (2007) 578–589.
Knutsson, A.: Health disorders of shift workers. Occup Med (Lond) 53 (2003) 103–108.
Mallis, M.M., et al.: Summary of the key features of seven biomathematical models of human fatigue and performance. Aviat Space and Env Med 75 (2004) A4–A14.
Hursh, S.R., et al..: Fatigue models for applied research in warfighting. Aviat Space and Env Med 75 (2004) A44–A53.
Borbély, A.A.: A two process model of sleep regulation. Hum Neurobiol 1 (1982) 195–204.
Saper, C.B., et al.: Sleep state switching. Neuron 68 (2010) 1023–1042.
Phillips, A.J.K. and Robinson, P.A.: A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system. J Biol Rhythms 22 (2007) 167–179.
Postnova, S., Voigt, K., Braun, H.A.: A mathematical model of homeostatic regulation of sleep-wake cycles by hypocretin/orexin. J Biol Rhythms 24 (2009) 523–535.
Kronauer, R.E., Forger, D.B., Jewett, M.E.: Quantifying human circadian pacemaker response to brief, extended, and repeated light stimuli over the phototopic range. J Biol Rhythms 14 (1999) 500–515.
Postnova, S., et al.: Exploring sleepiness and entrainment on permanent shift schedules in a physiologically based model. J Biol Rhythms 27 (2012) 91–102.
Lumley, M., et al.: The alerting effects of naps in sleep deprived subjects. Psycophysiol 23 (1986) 403–408.
St. Hilaire, M.A., Klerman, E.B., Khalsa, S.B.S., et al.: Addition of non-photic component to a light-based mathematical model of the human circadian pacemaker. J Theor Biol 247 (2007) 583–599.
Phillips, A.J.K., Chen, P.Y., Robinson, P.A.: Probing the mechanisms of chronotype using quantitative modeling. J Biol Rhythms 25 (2010) 217–227.
Moore, R.Y.: Suprachiasmatic nucleus in sleep-wake regulation. Sleep Med 8 (2007) 27–33.
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This work is supported by the Australian Research Council and National Health and Medical Research Council.
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© 2013 Springer Science+Business Media Dordrecht
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Postnova, S., Robinson, P.A. (2013). Forced Wakefulness for Entrainment to Permanent Shift Work: A Computational Study. In: Yamaguchi, Y. (eds) Advances in Cognitive Neurodynamics (III). Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4792-0_15
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DOI: https://doi.org/10.1007/978-94-007-4792-0_15
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