Abstract
The Middle East is one of the regions in the world where relatively high concentrations of atmospheric particulate matter (PM) have been detected frequently. It has been suggested that PM levels in the Middle East are present at levels that lead to adverse health effects and to poor visibility. In the current study, we summarize results published by our group over the last decade and introduce new data which demonstrate the extent of trans-boundary PM transport, and the fact that synoptic conditions control its chemical and mineralogical composition and might also affect its toxicity.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Adamson IYR, Prieditis H, Hedgecock C, Vincent R (2000) Zinc is the toxic factor in the lung response to an atmospheric particulate sample. Toxicol Appl Pharmacol 166:111–119
Alexandrova OA, Boyer DL, Anderson JR, Fernando HJS (2003) The influence of thermally driven circulation on PM10 concentration in the Salt Lake Valley. Atmos Environ 37:421–437
Auffan M, Achouak W, Rose J, Roncato MA, Chane C, Waite DT, Masion A, Woicik JC, Wiesner MR, Bottero JY (2008) Relation between the redox state of iron-based nanoparticles and their cytotoxicity toward Escherichia coli. Environ Sci Technol 42:6730–6735
Bell ML, Ebisu K, Peng RD, Samet JM, Dominici F (2009) Hospital admissions and chemical composition of fine particle air pollution. Am J Respir Crit Care Med 179:1115–1120
Binkova B, Lenicek J, Benes I, Vidova P, Gajdo O, Fried M, Sram RJ (1998) Genotoxicity of coke-oven and urban air particulate matter in vitro cellular assays coupled with – postlabeling and HPLC analysis of DNA adducts. Mutat Res/Genet Toxicol Environ Mutagen 414:77–94
Brook RD, Rajagopalan S, Pope CA, Brook JR, Bhatnagar A, Diez-Roux AV, Holguin F, Hong Y, Luepker RV, Mittleman MA et al (2010) Particulate matter air pollution and cardiovascular disease. Circulation 121:2331–2378
Buchholz S, Junk J, Krein A, Heinemann G, Hoffmann L (2010) Air pollution characteristics associated with mesoscale atmospheric patterns in northwest continental Europe. Atmos Environ 44:5183–5190
Cai C, Hogrefe C, Katsafados P, Kallos G, Beauharnois M, Schwab JJ, Ren X, Brune WH, Zhou X, He Y, Demerjian KL (2008) Performance evaluation of an air quality forecast modeling system for a summer and winter season – photochemical oxidants and their precursors. Atmos Environ 42(37):8585–8599
Cao Y, Frey HC (2011) Geographic differences in inter-individual variability of human exposure to fine particulate matter. Atmos Environ 45:5684–5691
Cheung KL, Ntziachristos L, Tzamkiozis T, Schauer JJ, Samaras Z, Moore KF, Sioutas C (2010) Emissions of particulate trace elements, metals and organic species from gasoline, diesel, and biodiesel passenger vehicles and their relation to oxidative potential. Aerosol Sci Technol 44:500–513
Cho AK, Sioutas C, Miguel AH, Kumagai Y, Schmitz DA, Singh M, Eiguren-Fernandez A, Froines JR (2005) Redox activity of airborne particulate matter at different sites in the Los Angeles Basin. Environ Res 99:40–47
Cohen AJ (2005) The global burden of disease due to outdoor air pollution. J Toxicol Environ Health A 68:1301–1307
Dayan U, Lamb D (2007) Influences of atmospheric circulation on the variability of wet sulfate deposition. Int J Climatol. doi:10.1002/joc
Dayan U, Levy I (2002) Relationship between synoptic-scale atmospheric circulation and ozone concentrations over Israel. J Geophys Res 107(D24):4813. doi:2002JD00214
Dayan U, Levy I (2005) The influence of seasonal meteorological conditions and atmospheric circulation types on PM10 and visibility in Tel-Aviv, Israel. J Appl Meteorol 44:606–619
Dayan AD, Paine AJ (2001) Mechanisms of chromium toxicity, carcinogenicity and allergenicity: review of the literature from 1985 to 2000. Hum Exp Toxicol 20:439–451
Dayan U, Heffter J, Miller B, Gutman G (1991) Dust intrusion events into the Mediterranean basin. J Appl Meteorol 30(8):1185–1199
Dayan U, Lifshitz-Goldreich B, Pick K (2002) Spatial and structural variation of the atmospheric boundary layer during summer in Israel – profiler and Rawinsonde measurements. J Appl Meteorol 41:447–457
Dayan U, Ziv B, Shoop T, Enzel Y (2007) Suspended dust over South-Eastern Mediterranean and its relation to atmospheric circulations. Int J Climatol. doi:10.1002/joc.1587
Dayan U, Tubi A, Levy I (2011) On the importance of synoptic classification methods with respect to environmental phenomena. Int J Climatol. doi:10.1002/joc.2297
Delfino R, Staimer N, Tjoa T, Arhami M, Polidori A, Gillen DL, George SC, Shafer MM, Schauer JJ, Sioutas C (2010) Associations of primary and secondary organic aerosols with airway and systemic inflammation in an elderly panel cohort. Epidemiology 21:892–902
Demuzere M, van Lipzig NPM (2010) A new method to estimate air-quality levels using a synoptic-regression approach. Part I: present-day O3 and PM10 analysis. Atmos Environ 44:1341–1355
Dockery DW, Pope CA, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG, Speizer FE (1993) An association between air pollution and mortality in six US cities. N Engl J Med 329:1753–1759
Donaldson K, Brown DM, Mitchell C, Dineva M, Beswick PH, Gilmour P, MacNee W (1997) Free radical activity of PM10: iron-mediated generation of hydroxyl radicals. Environ Health Perspect 105:1285–1289
Drori R, Dayan U, Edwards DP, Emmons LK, Erlick C (2012) Attributing and quantifying carbon monoxide sources affecting the Eastern Mediterranean: a combined satellite, modelling, and synoptic analysis study. Atmos Chem Phys 12:1067–1082
Erel Y, Axelrod T, Veron A, Mahrer Y, Katsafados P, Dayan U (2002) Trans-boundary atmospheric lead pollution. Environ Sci Technol 36:3230–3233
Erel Y, Dayan U, Rabi R, Rudich Y, Stein M (2006) Trans boundary transport of pollutants by atmospheric mineral dust. Environ Sci Technol 40:2996–3005
Erel Y, Kalderon-Asael B, Dayan U, Sandler A (2007) European atmospheric pollution imported by cooler air masses to the Eastern Mediterranean during the summer. Environ Sci Technol 41:5198–5203
Falkovich AH, Schkolnik G, Ganor E, Rudich Y (2004) Adsorption of organic compounds pertinent to urban environments onto mineral dust particles. J Geophys Res-Atmos 109(D2):1–19
Filippelli GM, Laidlaw MAS, Latimer JC, Raftis R (2005) Urban lead poisoning and medical geology: an unfinished story. GSA Today 15:4–11
Fleming ZL, Monks PS, Manning AJ (2011) Review: untangling the influence of air-mass history in interpreting observed atmospheric composition. Atmos Res 104–105:1–39
Gonzalez-Flecha B (2004) Oxidant mechanisms in response to ambient air particles. Mol Aspects Med 25:169–182
Guzmán-Torres D, Eiguren-Fernández A, Cicero-Fernández P, Maubert-Franco M, Retama-Hernández A, Ramos Villegas R, Miguel AH (2009) Effects of meteorology on diurnal and nocturnal levels of priority polycyclic aromatic hydrocarbons and elemental and organic carbon in PM10 at a source and a receptor area in Mexico City. Atmos Environ 43:2693
Israel Ministry of the Environment (2003) A comparative assessment of air pollution public health risks in two Israeli metropolitan areas: 1995–1999. Rep. 1222 in cooperation with Israel Union for Environmental Defense, Tel-Aviv Municipality, Ashdod-Yavne Regional Association of Towns for Environmental Protection, and US Environmental Protection Agency, 94 pp
Jimenez LA, Thompson J, Brown DA, Rahman I, Antonicelli F, Duffin R, Drost EM, Hay RT, Donaldson K, MacNee W (2000) Activation of NF-B by PM10 occurs via an iron-mediated mechanism in the absence of I B degradation. Toxicol Appl Pharmacol 166:101–110
Kalderon-Asael B, Erel Y, Sandler A, Dayan U (2009) Mineralogical and chemical characterization of suspended atmospheric particles over the east Mediterranean based on synoptic-scale circulation patterns. Atmos Environ 43(25):3963–3970
Karsenty E (2007) The health impact of atmospheric pollution of suspended particles – a literature review for the ministry for environmental protection (in Hebrew)
Kassomenos P, Gryparis A, Samoli E, Katsouyanni K, Lykoudis S, Flocas HA (2001) Atmospheric circulation types and daily mortality in Athens, Greece. Environ Health Perspect 109:591–596
Kennedy T, Ghio AJ, Reed W, Samet J, Zagorski J, Quay J, Carter J, Dailey L, Hoidal JR, Devlin RB (1998) Copper-dependent inflammation and nuclear factor-kappaB activation by particulate air pollution. Am J Respir Cell Mol Biol 19:366–378
Kessler N, Schauer JJ, Yagur-Kroll S, Melamed S, Tirosh O, Belkin S, Erel Y (2012) Development of a bacterial bioreporter panel to measure cytotoxicity of atmospheric particulate matter and related particulate matter emissions
Klein J, Post K, Seidel A, Frank H, Oesch F, Platt KL (1992) Quinone reduction and redox cycling catalysed by purified rat liver dihydrodiol/3 [alpha]-hydroxysteroid dehydrogenase. Biochem Pharmacol 44:341–349
Laden F, Schwartz J, Speizer FE, Dockery DW (2006) Reduction in fine particulate air pollution and mortality extended follow-up of the Harvard six cities study. Am J Respir Crit Care Med 173:667–672
Laidlaw MAS, Filippelli GM (2008) Resuspension of urban soils as a persistent source of lead poisoning in children: a review and new directions. Appl Geochem. doi:10.1016/j.apgeochem.2008.05.009
Lelieveld J, Berresheim H, Borrmann S, Crutzen PJ, Dentener FJ, Fischer H, Feichter J, Flatau PJ, Heland J, Holzinger R, Korrmann R, Lawrence MG, Levin Z, Markowicz KM, Mihalopoulos N, Minikin A, Ramanathan V, Reus MD, Roelofs GJ, Scheeren HA, Sciare J, Schlager H, Schultz M, Siegmund P, Steil B, Stephanou EG, Stier P, Traub M, Warneke C, Williams J, Ziereis H (2002) Global air pollution crossroads over the Mediterranean. Science 298:794–799
Levy I, Dayan U, Mahrer I (2008) A 5-yr study of the coastal recirculation and its effect on air pollutants over the East Mediterranean region. J Geophys Res 113. doi:10.1029/07JD009529
Levy I, Mahrer Y, Dayan U (2009a) Coastal and synoptic recirculation affecting air pollutants dispersion: a numerical study. Atmos Environ 43(12):1991–1999
Levy I, Dayan U, Mahrer I (2009b) Differing atmospheric scales of motion and their impact on air pollutants. Int J Climatol. doi:10.1002/joc.1905
Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A (2003) Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect 111:455–456
Lipfert FW, Murray CJ (2012) Air pollution and daily mortality: a new approach to an old problem. Atmos Environ 55:467–474
Luria M, Peleg M, Sharf G, Siman Tov-Alper D, Spitz N, Ben Ami Y, Gawii Z, Lifschitz B, Yitzchaki A, Seter I (1996) Atmospheric sulfur over the east Mediterranean region. J Geophys Res 101D:25,917–25,930
Markovic MZ, Hayden KL, Murphy JG, Makar PA, Ellis RA, Chang RYW, Slowik JG, Mihele C, Brook J (2011) The effect of meteorological and chemical factors on the agreement between observations and predictions of fine aerosol composition in southwestern Ontario during BAQS-Met. Atmos Chem Phys 11:3195–3210
Matvev V, Dayan U, Tass I, Peleg M (2002) Atmospheric sulfur flux rates to and from Israel. Sci Total Environ 291:143–154
Meng Q, Fan Z, Buckley B, Lin L, Huang L, Yu C-H, Stiles R, Bonanno L (2011) Development and evaluation of a method for hexavalent chromium in ambient air using IC-ICP-MS. Atmos Environ 45(12):2021–2027
Moulin C, Lambert CE, Dulac F, Dayan U (1997) Control of atmospheric export of dust from North Africa by the North Atlantic oscillation. Nature 387:691–694
Moulin C, Lamber CE, Dayan U, Masson V, Ramonet M, Bousquet P, Legrand M, Balkanski YJ, Guelle W, Marticorena B, Bergametti G, Dulac F (1998) Satellite climatology of African dust transport in the Mediterranean atmosphere. J Geophys Res 103(D11):13137–13144
Nel A (2005) Atmosphere enhanced: air pollution-related illness: effects of particles. Science 308:804–806
Neubergera M, Rabczenkob D, Moshammer H (2007) Extended effects of air pollution on cardiopulmonary mortality in Vienna. Atmos Environ 41:8549–8556
Oberdorster G, Stone V, Donaldson K (2007) Toxicology of nanoparticles: a historical perspective. Nanotoxicology 1:2–25
Penning TM (1993) Dihydrodiol dehydrogenase and its role in polycyclic aromatic hydrocarbon metabolism. Chem Biol Interact 89:1–34
Pope CA III, Ezzati M, Dockery DW (2009) Fine-particulate air pollution and life expectancy in the United States. N Engl J Med 360:376–386
Prahalad AK, Soukup JM, Inmon J, Willis R, Ghio AJ, Becker S, Gallagher JE (1999) Ambient air particles: effects on cellular oxidant radical generation in relation to particulate elemental chemistry. Toxicol Appl Pharmacol 158:81–91
Ren C, Park SK, Vokonas PS, Sparrow D, Wilker E, Baccarelli A, Suh HH, Tucker KL, Wright RO, Schwartz J (2010) Air pollution and homocysteine: more evidence that oxidative stress-related genes modify effects of particulate air pollution. Epidemiology 21:198–206
Riley MR, Boesewetter DE, Kim AM, Sirvent FP (2003) Effects of metals Cu, Fe, Ni, V, and Zn on rat lung epithelial cells. Toxicology 190:171–184
Rudich Y, Kaufman J, Dayan U, Hongbin Y, Kleidman RG (2008) Estimation of transboundary transport of pollution aerosols by remote sensing in the eastern Mediterranean. J Geophys Res Atmos 113(D14):D14S13
Salvi M, Holgate D (1999) Mechanisms of particulate matter toxicity. Clin Exp Allergy 29:1187–1194. doi:10.1046/j.1365-2222.1999.00576.x
Samet JM, Dominici F, Curriero FC, Coursac I, Zeger SL (2000) Fine particulate air pollution and mortality in 20 US cities, 1987–1994. N Engl J Med 343:1742–1749
Sarnat JA, Moise T, Shpund J, Liu Y, Pachon JE, Qasrawi R, Abdeen Z, Brenner S, Nassar K, Schauer JJ (2010) Assessing the spatial and temporal variability of fine particulate matter components in Israeli, Jordanian, and Palestinian cities. Atmos Environ 44:2383–2392
Sfetsos A, Vlachogiannis D (2010) A new approach to discovering the causal relationship between meteorological patterns and PM10 exceedances. Atmos Res 98:500–511
Shafer MM, Perkins DA, Antkiewicz DS, Stone EA, Quraishi TA, Schauer JJ (2010) Reactive oxygen species activity and chemical speciation of size-fractionated atmospheric particulate matter from Lahore, Pakistan: an important role for transition metals. J Environ Monit 12. doi:10.1039/b915008k
Shukla A, Timblin C, BeruBe K, Gordon T, McKinney W, Driscoll K, Vacek P, Mossman BT (2000) Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related genes and oxidant-dependent NF-kappaB activation in vitro. Am J Respir Cell Mol Biol 23:182–187
Siefert R, Pehkonen S, Erel Y, Hoffmann MR (1994) Photoproduction of H2O2 in aqueous suspensions of ambient aerosol with oxalate. Geochim Cosmochim Acta 58:3271–3280
Stanek LW, Sacks JD, Dutton SJ, Dubois JJB (2011) Attributing health effects to apportioned components and sources of particulate matter: an evaluation of collective results. Atmos Environ 45(32):5655–5663
Sumner ER, Shanmuganathan A, Sideri TC, Willetts SA, Houghton JE, Avery SV (2005) Oxidative protein damage causes chromium toxicity in yeast. Microbiology 151:1939–1948
Tai APK, Mickley LJ, Jacob DJ (2010) Correlations between fine particulate matter (PM2.5) and meteorological variables in the United States: implications for the sensitivity of PM2.5 to climate change. Atmos Environ 44:3976–3984
Tandon A, Yadav S, Attri AK (2010) Coupling between meteorological factors and ambient aerosol load. Atmos Environ 44:1237–1243
Tiea X, Wub D, Brasseura G (2009) Lung cancer mortality and exposure to atmospheric aerosol particles in Guangzhou, China. Atmos Environ 43:2375–2377
Topinka J, Schwarz LR, Wiebel FJ, Cerna M, Wolff T (2000) Genotoxicity of urban air pollutants in the Czech Republic Part II. DNA adduct formation in mammalian cells by extractable organic matter. Mutat Res Genet Toxicol Environ Mutagen 469:83–93
Triantafyllou AG (2001) PM10 pollution episodes as a function of synoptic climatology in a mountainous industrial area. Environ Pollut 112:491–500
Turoczi B, Hoffer A, Toth A, Kovats N, Acs A, Ferincz A, Kovacs A, Gelencser A (2012) Comparative assessment of ecotoxicity of urban aerosol. Atmos Chem Phys Discuss 12:8533–8546
Van Maanen JMS, Borm PJA, Knaapen A, van Herwijnen M, Schilderman PAEL, Smith KR, Aust AE, Tomatis M, Fubini B (1999) In vitro effects of coal fly ashes: hydroxyl radical generation, iron release, and DNA damage and toxicity in rat lung epithelial cells. Inhal Toxicol 11:1123–1141
Vedal S, Hannigan MP, Dutton SJ, Miller SL, Milford JB, Rabinovitch N, Kim SY, Sheppard L (2009) The Denver Aerosol Sources and Health (DASH) study: overview and early findings. Atmos Environ 43(9):1666–1673
Velders GJM, Matthijsen J (2009) Meteorological variability in NO2 and PM10 concentrations in the Netherlands and its relation with EU limit values. Atmos Environ 43:3858–3866
Vinzents PS, Moller P, Sorensen M, Knudsen LE, Hertel O, Jensen FP, Schibye B, Loft S (2005) Personal exposure to ultrafine particles and oxidative DNA damage. Environ Health Perspect 113:1485
Wanger A, Peleg M, Sharf G, Mahrer Y, Dayan U, Kallos G, Kotroni V, Lagouvardos K, Varinou M, Papadopoulos A, Luria M (2000) Some observational and modeling evidence of long range transport of air pollutants from Europe towards the Israeli coast. J Geophys Res 105(D6):7177–7186
Xia T, Korge P, Weiss JN, Li N, Venkatesen MI, Sioutas C, Nel A (2004) Quinones and aromatic chemical compounds in particulate matter (PM) induce mitochondrial dysfunction: implications for ultrafine particle toxicity. Environ Health Perspect 112:1347–1358
Yang YQ, Hou Q, Zhou CH, Liu HL, Wang YQ, Niu T (2007) Sand/dust storms over Northeast Asia and associated large-scale circulations in spring 2006. Atmos Chem Phys Discuss 7:9259–9281
Young TM, Heerman DA, Sirin G, Ashbaugh LL (2002) Resuspension of soil as a source of airborne lead near industrial facilities and highways. Environ Sci Technol 36:2484–2490
Acknowledgments
We thank our past students T. Axelrod, J. Jandorf, B. Kalderon, and R. Rabi. We also thank S. Bookman, R. Nissan, E. Refaeli, and D. Stern of the Hebrew University and L. Halitz, S. Ehrlich, O. Yoffe, I. Segal, and N. Teutsch of the Geological Survey of Israel for technical assistance. Financial support for this research was provided by the Israeli Science Foundation, the Israeli Ministry of Environmental Protection, and by the Environmental Health Fund.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media Dordrecht.
About this chapter
Cite this chapter
Erel, Y. et al. (2013). Atmospheric Particulate Matter (PM) in the Middle East: Toxicity, Trans-boundary Transport, and Influence of Synoptic Conditions. In: Censi, P., Darrah, T., Erel, Y. (eds) Medical Geochemistry. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4372-4_3
Download citation
DOI: https://doi.org/10.1007/978-94-007-4372-4_3
Published:
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-007-4371-7
Online ISBN: 978-94-007-4372-4
eBook Packages: Earth and Environmental ScienceEarth and Environmental Science (R0)